Defined stereoisomers of 2″-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure–Activity Relationship Study

(2016) Matthias Schiedel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

(2016) B. A. Gibson et al.   SCIENCE

Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation

(2015) Jessica L. Feldman et al.   BIOCHEMISTRY

Sirtuins in Epigenetic Regulation

(2015) Hui Jing et al.   CHEMICAL REVIEWS

The chemical biology of sirtuins

(2015) Bing Chen et al.   CHEMICAL SOCIETY REVIEWS

Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases

(2015) Giulia Pergolizzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Sirtuin inhibitors as anticancer agents

(2014) Jing Hu et al.   Future Medicinal Chemistry

Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies

(2014) Xiangying Guan et al.   PLoS One

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Analysis of Human SIRT1

(2013) Andrew M. Davenport et al.   JOURNAL OF MOLECULAR BIOLOGY

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel fluorescent probe for NAD-consuming enzymes

(2011) Giulia Pergolizzi et al.   CHEMICAL COMMUNICATIONS

Two-Step Synthesis of Novel, Bioactive Derivatives of the Ubiquitous Cofactor Nicotinamide Adenine Dinucleotide (NAD)

(2011) Thomas Pesnot et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Clickable NAD Analogues for Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases

(2010) Hong Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering

(2010) A. E. Lang et al.   SCIENCE

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogues and32P-NAD†

(2009) Jintang Du et al.   BIOCHEMISTRY

Diastereocontrolled Electrophilic Fluorinations of 2-Deoxyribonolactone: Syntheses of All Corresponding 2-Deoxy-2-fluorolactones and 2′-Deoxy-2′-fluoro-NAD+s

(2009) Yana Cen et al.   JOURNAL OF ORGANIC CHEMISTRY

Transcriptional targets of sirtuins in the coordination of mammalian physiology

(2008) Jerome N Feige et al.   CURRENT OPINION IN CELL BIOLOGY