Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies
出版年份 2022 全文链接
标题
Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies
作者
关键词
-
出版物
ADVANCED DRUG DELIVERY REVIEWS
Volume 187, Issue -, Pages 114342
出版商
Elsevier BV
发表日期
2022-05-13
DOI
10.1016/j.addr.2022.114342
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Injectable Hydrogels: From Laboratory to Industrialization
- (2021) Jose Maria Alonso et al. Polymers
- Thermo-Responsive PLGA-PEG-PLGA Hydrogels as Novel Injectable Platforms for Neuroprotective Combined Therapies in the Treatment of Retinal Degenerative Diseases
- (2021) José Javier López-Cano et al. Pharmaceutics
- Treatments for dry age-related macular degeneration: therapeutic avenues, clinical trials and future directions
- (2021) Thales Antonio Cabral de Guimaraes et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles
- (2020) Hiroki Tsujinaka et al. Nature Communications
- Safety and Biocompatibility of Aflibercept-Loaded Microsphere Thermo-Responsive Hydrogel Drug Delivery System in a Nonhuman Primate Model
- (2020) Soohyun Kim et al. Translational Vision Science & Technology
- Injectable biodegradable bi-layered capsule for sustained delivery of bevacizumab in treating wet age-related macular degeneration
- (2020) Pengfei Jiang et al. JOURNAL OF CONTROLLED RELEASE
- Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes
- (2020) Hyeong Min Kim et al. Translational Vision Science & Technology
- Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations
- (2020) Rubén Varela-Fernández et al. Pharmaceutics
- Potential of subconjunctival aflibercept in treating choroidal neovascularization
- (2020) Jayabalan Nirmal et al. EXPERIMENTAL EYE RESEARCH
- Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy
- (2020) Raphael Mietzner et al. Pharmaceutics
- Nanodelivery of Resveratrol-Loaded PLGA Nanoparticles for Age-Related Macular Degeneration
- (2020) Priyanka Bhatt et al. AAPS PHARMSCITECH
- Foreign Body Reaction, Retinal Degeneration, and Epiretinal Membranes Associated With Intravitreal Administration of PLGA Rods
- (2020) Helen Booler et al. TOXICOLOGIC PATHOLOGY
- Angiogenesis-Inflammation Cross Talk in Diabetic Retinopathy: Novel Insights From the Chick Embryo Chorioallantoic Membrane/Human Vitreous Platform
- (2020) Sara Rezzola et al. Frontiers in Immunology
- Efficacy and Safety of a Proposed Ranibizumab Biosimilar Product vs a Reference Ranibizumab Product for Patients With Neovascular Age-Related Macular Degeneration
- (2020) Se Joon Woo et al. JAMA Ophthalmology
- Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques
- (2020) Margaux Vigata et al. Pharmaceutics
- Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study
- (2020) Jaimie D Steinmetz et al. Lancet Global Health
- Morphology and Composition of the Inner Limiting Membrane: Species-Specific Variations and Relevance toward Drug Delivery Research
- (2019) Karen Peynshaert et al. CURRENT EYE RESEARCH
- Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma
- (2019) A. Arranz-Romera et al. JOURNAL OF CONTROLLED RELEASE
- Intravitreal dexamethasone implant Ozurdex® in naïve and refractory patients with different subtypes of diabetic macular edema
- (2019) Verónica Castro-Navarro et al. BMC Ophthalmology
- A biocompatible reverse thermoresponsive polymer for ocular drug delivery
- (2019) Asitha Balachandra et al. DRUG DELIVERY
- An overview on the mathematical modeling of hydrogels’ behavior for drug delivery systems
- (2019) Diego Caccavo INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Thermosensitive hydrogel-based drug delivery system for sustained drug release
- (2019) Pratikkumar Patel et al. JOURNAL OF POLYMER RESEARCH
- Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization
- (2019) Jayoung Kim et al. Acta Biomaterialia
- Hydrogels for sustained delivery of biologics to the back of the eye
- (2019) Debby Chang et al. DRUG DISCOVERY TODAY
- The safety evaluation of long-acting ocular delivery systems
- (2019) Evan A. Thackaberry et al. DRUG DISCOVERY TODAY
- Investigating impacts of surface charge on intraocular distribution of intravitreal lipid nanoparticles
- (2019) Xiaonan Huang et al. EXPERIMENTAL EYE RESEARCH
- Abicipar pegol—a novel anti-VEGF therapy with a long duration of action
- (2019) Elad Moisseiev et al. EYE
- Hydrogels Based on Schiff Base Linkages for Biomedical Applications
- (2019) Junpeng Xu et al. MOLECULES
- Anti-Angiogenic Activity Of Bevacizumab-Bearing Dexamethasone-Loaded PLGA Nanoparticles For Potential Intravitreal Applications
- (2019) Jiaxin Liu et al. International Journal of Nanomedicine
- Tight Junctions of the Outer Blood Retina Barrier
- (2019) Aisling Naylor et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: Current status and challenges
- (2018) Chi Ming Laurence Lau et al. ADVANCED DRUG DELIVERY REVIEWS
- Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia
- (2018) Di Huang et al. BIOMATERIALS
- Biopolymer-based strategies in the design of smart medical devices and artificial organs
- (2018) Lina Altomare et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties
- (2018) Alyona Sukhanova et al. Nanoscale Research Letters
- Polymeric, injectable, intravitreal hydrogel devices for posterior segment applications and interventions
- (2018) Muhammed Anwary et al. Artificial Cells Nanomedicine and Biotechnology
- Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties
- (2018) Alyona Sukhanova et al. Nanoscale Research Letters
- Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Bioactive Aflibercept In Vitro
- (2018) Wenqiang Liu et al. CURRENT EYE RESEARCH
- Functional Hydrogels With Tunable Structures and Properties for Tissue Engineering Applications
- (2018) Xiaomeng Li et al. Frontiers in Chemistry
- Pharmacokinetic Simulations of Intravitreal Biologicals: Aspects of Drug Delivery to the Posterior and Anterior Segments
- (2018) Anna-Kaisa Rimpelä et al. Pharmaceutics
- Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery
- (2017) Rohit Bisht et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye
- (2017) Devin Tesar et al. mAbs
- Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone)
- (2017) Tomomi Masuda et al. Oxidative Medicine and Cellular Longevity
- Pharmacokinetic aspects of retinal drug delivery
- (2017) Eva M. del Amo et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis
- (2017) Seth R Flaxman et al. Lancet Global Health
- Tear film lipid layer: A molecular level view
- (2016) Lukasz Cwiklik BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Controlled and Extended In Vitro Release of Bioactive Anti-Vascular Endothelial Growth Factors from a Microsphere-Hydrogel Drug Delivery System
- (2016) Christian R. Osswald et al. CURRENT EYE RESEARCH
- Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
- (2016) Jörg T Regula et al. EMBO Molecular Medicine
- Light-responsivein situforming injectable implants for effective drug delivery to the posterior segment of the eye
- (2016) Rohit Bisht et al. Expert Opinion on Drug Delivery
- Therapeutic effect of apatinib-loaded nanoparticles on diabetes-induced retinal vascular leakage
- (2016) Wonhee Suh et al. International Journal of Nanomedicine
- Dexamethasone - PAMAM dendrimer conjugates for retinal delivery: preparation, characterization andin vivoevaluation
- (2016) Burçin Yavuz et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab
- (2016) Naba Elsaid et al. MOLECULAR PHARMACEUTICS
- Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab
- (2016) Whitney Shatz et al. MOLECULAR PHARMACEUTICS
- The progress in understanding and treatment of diabetic retinopathy
- (2016) Alan W. Stitt et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Ocular Biocompatibility of Poly-N-Isopropylacrylamide (pNIPAM)
- (2016) Luiz H. Lima et al. Journal of Ophthalmology
- Thiol–ene Click Hydrogels for Therapeutic Delivery
- (2016) Prathamesh M. Kharkar et al. ACS Biomaterials-Science & Engineering
- Thiol–ene Click Hydrogels for Therapeutic Delivery
- (2016) Prathamesh M. Kharkar et al. ACS Biomaterials Science & Engineering
- Designing hydrogels for controlled drug delivery
- (2016) Jianyu Li et al. Nature Reviews Materials
- Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
- (2015) Kan Yue et al. BIOMATERIALS
- Diffusion Regulation in the Vitreous Humor
- (2015) Benjamin Tillmann Käsdorf et al. BIOPHYSICAL JOURNAL
- Intracellular delivery of dendrimer triamcinolone acetonide conjugates into microglial and human retinal pigment epithelial cells
- (2015) Siva P. Kambhampati et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Intravitreal clearance and volume of distribution of compounds in rabbits: In silico prediction and pharmacokinetic simulations for drug development
- (2015) Eva M. del Amo et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Biomedical applications of hydrogels: A review of patents and commercial products
- (2015) Enrica Caló et al. EUROPEAN POLYMER JOURNAL
- Production methods and stabilization strategies for polymer-based nanoparticles and microparticles for parenteral delivery of peptides and proteins
- (2015) Naomi Teekamp et al. Expert Opinion on Drug Delivery
- Sustained-release fluocinolone acetonide intravitreal insert for macular edema: clinical pharmacology and safety evaluation
- (2015) Mohammad Ali Sadiq et al. Expert Opinion On Drug Safety
- An injectable thermosensitive polymeric hydrogel for sustained release of Avastin® to treat posterior segment disease
- (2015) Binbin Xie et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Collagen Structure and Mechanical Properties of the Human Sclera: Analysis for the Effects of Age
- (2015) Baptiste Coudrillier et al. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
- Recent progress in biomedical applications of Pluronic (PF127): Pharmaceutical perspectives
- (2015) Muhammad Sajid Hamid Akash et al. JOURNAL OF CONTROLLED RELEASE
- Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy
- (2015) Thomas F. Martens et al. JOURNAL OF CONTROLLED RELEASE
- Stimulus-responsive hydrogels: Theory, modern advances, and applications
- (2015) Michael C. Koetting et al. MATERIALS SCIENCE & ENGINEERING R-REPORTS
- Misdirected aqueous flow in rhegmatogenous retinal detachment: A pathophysiology update
- (2015) David Tabibian et al. SURVEY OF OPHTHALMOLOGY
- Immune mechanisms in inflammatory and degenerative eye disease
- (2015) Victor L. Perez et al. TRENDS IN IMMUNOLOGY
- An Update on Ocular Surface Epithelial Stem Cells: Cornea and Conjunctiva
- (2015) Tiago Ramos et al. Stem Cells International
- Role of Physicochemical Properties in Nanoparticle Toxicity
- (2015) Seung Shin et al. Nanomaterials
- Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study
- (2015) Yu Yu et al. Translational Vision Science & Technology
- Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering
- (2014) Yanjiao Jiang et al. BIOMATERIALS
- Intravitreal controlled release of dexamethasone from engineered microparticles of porous silicon dioxide
- (2014) Chengyun Wang et al. EXPERIMENTAL EYE RESEARCH
- Intravitreal drug delivery in retinal disease: are we out of our depth?
- (2014) Sachin S Thakur et al. Expert Opinion on Drug Delivery
- Monthly OCT monitoring of Ozurdex for macular oedema related to retinal vascular diseases: re-treatment strategy (OCTOME Report 1)
- (2014) R Mathew et al. EYE
- In situ covalently cross-linked PEG hydrogel for ocular drug delivery applications
- (2014) Jing Yu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A Combined Micelle and Poly(Serinol Hexamethylene Urea)-Co-Poly(N-Isopropylacrylamide) Reverse Thermal Gel as an Injectable Ocular Drug Delivery System
- (2014) Amin Famili et al. MACROMOLECULAR BIOSCIENCE
- Dendrimers: synthesis, applications, and properties
- (2014) Elham Abbasi et al. Nanoscale Research Letters
- Randomized Trial of Ciliary Neurotrophic Factor Delivered by Encapsulated Cell Intraocular Implants for Retinitis Pigmentosa
- (2013) David G. Birch et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide
- (2013) Ron B. Shmueli et al. BIOMATERIALS
- Macroscopic motion of supramolecular assemblies actuated by photoisomerization of azobenzene derivatives
- (2013) Yoshiyuki Kageyama et al. CHEMICAL COMMUNICATIONS
- The protective effect of albumin on bevacizumab activity and stability in PLGA nanoparticles intended for retinal and choroidal neovascularization treatments
- (2013) Reyhaneh Varshochian et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Adverse events and complications associated with intravitreal injection of anti-VEGF agents: a review of literature
- (2013) K Ghasemi Falavarjani et al. EYE
- Sustained release of avastin® from polysaccharides cross-linked hydrogels for ocular drug delivery
- (2013) Xu Xu et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo
- (2013) Qingguo Xu et al. JOURNAL OF CONTROLLED RELEASE
- Immunogenicity of therapeutic proteins: Influence of aggregation
- (2013) Kirsty D. Ratanji et al. Journal of Immunotoxicology
- Dendrimer Nanoparticles for Ocular Drug Delivery
- (2013) Siva P. Kambhampati et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- An Anti-angiogenic Reverse Thermal Gel as a Drug-Delivery System for Age-Related Wet Macular Degeneration
- (2013) Daewon Park et al. MACROMOLECULAR BIOSCIENCE
- Nanoparticles in Porous Microparticles Prepared by Supercritical Infusion and Pressure Quench Technology for Sustained Delivery of Bevacizumab
- (2013) Sarath K. Yandrapu et al. MOLECULAR PHARMACEUTICS
- Twelve-Month Efficacy and Safety of 0.5 mg or 2.0 mg Ranibizumab in Patients with Subfoveal Neovascular Age-related Macular Degeneration
- (2013) Brandon G. Busbee et al. OPHTHALMOLOGY
- The Effect of Glutathione as Chain Transfer Agent in PNIPAAm-Based Thermo-responsive Hydrogels for Controlled Release of Proteins
- (2013) Pawel W. Drapala et al. PHARMACEUTICAL RESEARCH
- The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection
- (2012) Heebeom Koo et al. BIOMATERIALS
- Polymeric Conjugates for Drug Delivery
- (2012) Nate Larson et al. CHEMISTRY OF MATERIALS
- Low molecular weight oligochitosans for non-viral retinal gene therapy
- (2012) G. Puras et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A covalently crosslinked polysaccharide hydrogel for potential applications in drug delivery and tissue engineering
- (2012) Xingyi Li et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Nanostructured Thin Film Polymer Devices for Constant-Rate Protein Delivery
- (2012) Daniel A. Bernards et al. NANO LETTERS
- Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration
- (2012) Daniel F. Martin et al. OPHTHALMOLOGY
- PHARMACOKINETIC COMPARISON OF KETOROLAC AFTER INTRACAMERAL, INTRAVITREAL, AND SUPRACHOROIDAL ADMINISTRATION IN RABBITS
- (2012) MeiZi Wang et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- ASSESSMENT OF THE DIFFERENCES IN PHARMACOKINETICS AND PHARMACODYNAMICS BETWEEN FOUR DISTINCT FORMULATIONS OF TRIAMCINOLONE ACETONIDE
- (2012) Leandro C. Zacharias et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Regenerative Biomaterials that “Click”: Simple, Aqueous-Based Protocols for Hydrogel Synthesis, Surface Immobilization, and 3D Patterning
- (2011) Chelsea M. Nimmo et al. BIOCONJUGATE CHEMISTRY
- Photoresponsive PEG-Anthracene Grafted Hyaluronan as a Controlled-Delivery Biomaterial
- (2011) Laura A. Wells et al. BIOMACROMOLECULES
- Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
- (2011) Raymond Iezzi et al. BIOMATERIALS
- Investigation of nanoparticles using magnetic resonance imaging after intravitreal injection
- (2011) Hemalatha B Raju et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Endophthalmitis following intravitreal injections
- (2011) Cristina Irigoyen et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Generic, Anthracene-Based Hydrogel Crosslinkers for Photo-controllable Drug Delivery
- (2011) Laura A. Wells et al. MACROMOLECULAR BIOSCIENCE
- Evaluation of Magnetic Micro- and Nanoparticle Toxicity to Ocular Tissues
- (2011) Hemalatha B. Raju et al. PLoS One
- Intravitreal Injection Technique
- (2011) Rishi R. Doshi et al. Seminars in Ophthalmology
- A functionalizable reverse thermal gel based on a polyurethane/PEG block copolymer
- (2010) Daewon Park et al. BIOMATERIALS
- Light controlled protein release from a supramolecular hydrogel
- (2010) Ke Peng et al. CHEMICAL COMMUNICATIONS
- Complications of intravitreal injections
- (2010) Kapil M Sampat et al. CURRENT OPINION IN OPHTHALMOLOGY
- Drug delivery to the posterior segment of the eye
- (2010) Thilini Rasika Thrimawithana et al. DRUG DISCOVERY TODAY
- Mechanisms of retinal ganglion cell injury and defense in glaucoma
- (2010) Juan Qu et al. EXPERIMENTAL EYE RESEARCH
- Barrier analysis of periocular drug delivery to the posterior segment
- (2010) Veli-Pekka Ranta et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable Implants for Sustained Drug Release in the Eye
- (2010) Susan S. Lee et al. PHARMACEUTICAL RESEARCH
- Protein delivery for retinal diseases: From basic considerations to clinical applications
- (2010) M. El Sanharawi et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Photocrosslinked alginate hydrogels with tunable biodegradation rates and mechanical properties
- (2009) Oju Jeon et al. BIOMATERIALS
- Recent trends in stabilising peptides and proteins in pharmaceutical formulation – considerations in the choice of excipients
- (2009) Lene Jorgensen et al. Expert Opinion on Drug Delivery
- Nanoparticle–integrin antagonist C16Y peptide treatment of choroidal neovascularization in rats
- (2009) Hyuncheol Kim et al. JOURNAL OF CONTROLLED RELEASE
- The Impact of PEGylation on Biological Therapies
- (2008) Francesco M Veronese et al. BIODRUGS
- Ophthalmic light sensitive nanocarrier systems
- (2008) J CHRISTIE et al. DRUG DISCOVERY TODAY
- Iluvien™: a new sustained delivery technology for posterior eye disease
- (2008) Frances E Kane et al. Expert Opinion on Drug Delivery
- Pharmacokinetic Study of Dexamethasone Disodium Phosphate using Intravitreal, Subconjunctival, and Intravenous Delivery Routes in Rabbits
- (2008) Kamran Hosseini et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Shape Induced Inhibition of Phagocytosis of Polymer Particles
- (2008) Julie A. Champion et al. PHARMACEUTICAL RESEARCH
- Hydrogels in drug delivery: Progress and challenges
- (2008) Todd R. Hoare et al. POLYMER
- Dexamethasone-loaded poly(ε-caprolactone) intravitreal implants: A pilot study
- (2007) S FIALHO EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Chemical Degradation of Peptides and Proteins in PLGA: A Review of Reactions and Mechanisms
- (2007) M.L. Houchin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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