Ganglioside Nanocluster-Targeting Peptidyl Inhibitor Prevents Amyloid β Fibril Formation on the Neuronal Membrane

Heterogeneous Ganglioside-Enriched Nanoclusters with Different Densities in Membrane Rafts Detected by a Peptidyl Molecular Probe

(2021) Teruhiko Matsubara et al.   LANGMUIR

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Alzheimer disease and aducanumab: adjusting our approach

(2019) Dennis J. Selkoe   Nature Reviews Neurology

Amyloid β fibrils assembled on ganglioside-enriched membranes contain both parallel β-sheets and turns

(2018) Teruhiko Matsubara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Responsibility of lipid compositions for the amyloid ß assembly induced by ganglioside nanoclusters in mouse synaptosomal membranes

(2018) Teruhiko Matsubara et al.   POLYMER JOURNAL

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

(2018) Ming Jin et al.   Nature Communications

Size and Shape of Amyloid Fibrils Induced by Ganglioside Nanoclusters: Role of Sialyl Oligosaccharide in Fibril Formation

(2017) Teruhiko Matsubara et al.   LANGMUIR

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

Structural and dynamic views of GM1 ganglioside

(2015) Maho Yagi-Utsumi et al.   GLYCOCONJUGATE JOURNAL

Imbalance in Fatty-Acid-Chain Length of Gangliosides Triggers Alzheimer Amyloid Deposition in the Precuneus

(2015) Naoto Oikawa et al.   PLoS One

Neuroimaging and Other Biomarkers for Alzheimer's Disease: The Changing Landscape of Early Detection

(2013) Shannon L. Risacher et al.   Annual Review of Clinical Psychology

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Density of GM1 in Nanoclusters Is a Critical Factor in the Formation of a Spherical Assembly of Amyloid β-Protein on Synaptic Plasma Membranes

(2013) Teruhiko Matsubara et al.   LANGMUIR

Pathological significance of ganglioside clusters in Alzheimer’s disease

(2011) Katsuhiko Yanagisawa   JOURNAL OF NEUROCHEMISTRY

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Sialic Acid-Mimic Peptides As Hemagglutinin Inhibitors for Anti-Influenza Therapy

(2010) Teruhiko Matsubara et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide

(2010) Ethan A. Merritt et al.   PROTEIN SCIENCE

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Inhibition of Influenza Virus Infections by Sialylgalactose-Binding Peptides Selected from a Phage Library

(2009) Teruhiko Matsubara et al.   JOURNAL OF MEDICINAL CHEMISTRY

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY