Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway

Kill Two Birds with One Stone: Role of the RIPK3 in Necroptosis and Inflammasome Activation

(2021) Sagar Paudel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways

(2021) Hao Yi et al.   Frontiers in Cell and Developmental Biology

AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice

(2021) Ya-chun Han et al.   Cell Death & Disease

Metformin: the updated protective property in kidney disease

(2020) Qingjun Pan et al.   Aging-US

Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice

(2020) Fei Cao et al.   Frontiers in Pharmacology

Update on the cellular and molecular aspects of lupus nephritis

(2020) Eleni Frangou et al.   CLINICAL IMMUNOLOGY

Pathogenic effects of inhibition of mTORC1/STAT3 axis facilitates Staphylococcus aureus-induced pyroptosis in human macrophages

(2020) Ruiyuan Yao et al.   Cell Communication and Signaling

Lupus nephritis: clinical presentations and outcomes in the 21st century

(2020) Michela Gasparotto et al.   RHEUMATOLOGY

Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation

(2019) Chaohuan Guo et al.   JOURNAL OF AUTOIMMUNITY

Ischemia Reperfusion Induces Death Receptor-Independent Necroptosis via Calpain-STAT3 Activation in a Lung Transplant Setting

(2018) Hyunhee Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD

(2018) Hui Chen et al.   Cell Death & Disease

Accelerated Glomerular Cell Senescence in Experimental Lupus Nephritis

(2018) Chen Yang et al.   MEDICAL SCIENCE MONITOR

Exclusive expression of transmembrane TNF aggravates acute glomerulonephritis despite reduced leukocyte infiltration and inflammation

(2018) Martin B. Müller et al.   KIDNEY INTERNATIONAL

Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease

(2017) Syamantak Majumder et al.   JOURNAL OF CLINICAL INVESTIGATION

Metformin Suppresses Systemic Autoimmunity inRoquinsan/sanMice through Inhibiting B Cell Differentiation into Plasma Cells via Regulation of AMPK/mTOR/STAT3

(2017) Seon-Yeong Lee et al.   JOURNAL OF IMMUNOLOGY

An Inflammatory Perspective on Necroptosis

(2017) Conor J. Kearney et al.   MOLECULAR CELL

Update on Lupus Nephritis

(2016) Salem Almaani et al.   Clinical Journal of the American Society of Nephrology

Nephroprotective Effects of Metformin in Diabetic Nephropathy

(2016) Sreenithya Ravindran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insights into the epidemiology and management of lupus nephritis from the US rheumatologist's perspective

(2016) Paul J. Hoover et al.   KIDNEY INTERNATIONAL

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney

(2016) Michael Christensen et al.   Scientific Reports

Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms: Figure 1

(2015) Yuichi Hattori et al.   DIABETES

Normalization of CD4 + T cell metabolism reverses lupus

(2015) Yiming Yin et al.   Science Translational Medicine

Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2

(2015) Wen Yue et al.   Oncotarget

The effect of cell death in the initiation of lupus nephritis

(2014) K. Fenton   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

(2011) Claudia Günther et al.   NATURE

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus

(2008) Hermine I. Brunner et al.   ARTHRITIS AND RHEUMATISM