Cell polarity defines three distinct domains in pancreatic β-cells

The Edges of Pancreatic Islet β Cells Constitute Adhesive and Signaling Microdomains

(2015) Erez Geron et al.   Cell Reports

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature

(2014) Jiun T. Low et al.   DIABETOLOGIA

LKB1 and AMPK differentially regulate pancreatic β-cell identity

(2014) Marina Kone et al.   FASEB JOURNAL

Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology

(2014) Anja Marciniak et al.   Nature Protocols

Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents

(2014) Jantje M. Gerdes et al.   Nature Communications

Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains

(2013) E. Denker et al.   DEVELOPMENT

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

(2013) Jiun T. Low et al.   DIABETOLOGIA

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

(2013) Benedetta Cerruti et al.   JOURNAL OF CELL BIOLOGY

Is Dynamic Autocrine Insulin Signaling Possible? A Mathematical Model Predicts Picomolar Concentrations of Extracellular Monomeric Insulin within Human Pancreatic Islets

(2013) Minghu Wang et al.   PLoS One

Polarity in Mammalian Epithelial Morphogenesis

(2013) J. Roignot et al.   Cold Spring Harbor Perspectives in Biology

Polarized sorting and trafficking in epithelial cells

(2012) Xinwang Cao et al.   CELL RESEARCH

LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo

(2010) Gao Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Unperturbed islet α-cell function examined in mouse pancreas tissue slices

(2010) Ya-Chi Huang et al.   JOURNAL OF PHYSIOLOGY-LONDON

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

LKB1 Regulates Pancreatic β Cell Size, Polarity, and Function

(2009) Zvi Granot et al.   Cell Metabolism

Loss of Lkb1 in Adult β Cells Increases β Cell Mass and Enhances Glucose Tolerance in Mice

(2009) Accalia Fu et al.   Cell Metabolism

Coordinated protein sorting, targeting and distribution in polarized cells

(2008) Ira Mellman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY