期刊
JOURNAL OF CELL SCIENCE
卷 129, 期 20, 页码 3935-3947出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/jcs.190975
关键词
Mitochondria; Protein translocation; Molecular evolution; Protein import; Plant molecular biology
类别
资金
- Humboldt Research Fellowship from the Alexander von Humboldt-Stiftung
Twin-arginine translocation (Tat) pathways have been well-characterized in bacteria and chloroplasts. Genes encoding a TatC protein are found in almost all plant mitochondrial genomes but to date these have not been extensively investigated. For the first time it could be demonstrated that this mitochondrial-encoded TatC is a functional gene that is translated into a protein in the model plant Arabidopsis thaliana. A TatB-like subunit localized to the inner membrane was also identified that is nuclear-encoded and is essential for plant growth and development, indicating that plants potentially require a Tat pathway for mitochondrial biogenesis.
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