Review
Chemistry, Analytical
Antonio Martin-Esteban
Summary: The use of molecularly imprinted polymers in sample preparation as selective sorbent materials has gained significant attention in recent years, leading to analytical methods with unprecedented selectivity. However, with the increasing adoption of Green Analytical Chemistry principles, it is important to critically review the greenness of synthesis and further application of molecularly imprinted polymers. This review discusses the preparation steps and strategies, reagents used, as well as their incorporation into microextraction techniques from a green perspective, and offers recent alternatives to enhance the sustainability of molecularly imprinted polymers.
JOURNAL OF SEPARATION SCIENCE
(2022)
Review
Chemistry, Multidisciplinary
Abbas Ostovan, Maryam Arabi, Yunqing Wang, Jinhua Li, Bowei Li, Xiaoyan Wang, Lingxin Chen
Summary: Molecular imprinting technology can produce artificial binding sites with precise complementarity to substrates, demonstrating exquisite molecular recognition. Greenificated molecularly imprinted polymers are a new class of plastic antibodies that achieve sustainability by following greenification principles and have wide-ranging applications.
ADVANCED MATERIALS
(2022)
Review
Biochemistry & Molecular Biology
Jiahe Chen, Maobin Wei, Minjia Meng
Summary: Molecularly imprinted membranes (MIMs) are used for separating and purifying the effective constituents of natural products. The trade-off relationship between flux and permselectivities is a challenging task for membranologists. The presence of effective high-density recognition sites and a high degree of matching between these sites and the imprinted cavity are the key factors in resolving this trade-off.
Review
Polymer Science
Chengya Dong, Hongxing Shi, Yuanrui Han, Yuanyuan Yang, Ruixin Wang, Jiying Men
Summary: Surface molecular imprinting technology (SMIT) has attracted extensive attention and been applied in various fields due to its desired selectivity and fast mass transfer rate, but faces challenges such as obtaining pure templates and high cost of using noble metals.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Chemistry, Analytical
Omur Acet, Samir Abbas Ali Noma, Burcu Onal Acet, Emrah Dikici, Bilgen Osman, Mehmet Odabasi
Summary: In this study, L-asparagine (L-Asn) imprinted membranes (L-Asn-MIPs) were synthesized for selective and efficient removal of L-Asn. The membrane was prepared using a functional monomer (acrylamide) and a comonomer (hydroxyethyl methacrylate). The membrane exhibited a high selectivity towards L-Asn and a maximum adsorption capacity of 408.2 mg/g at pH 7.2, 24°C.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Biochemistry & Molecular Biology
Huda S. Alsalem, M. Monier, May Abdullah Abomuti, Rua B. Alnoman, Hussam Y. Alharbi, Majed S. Aljohani, Soha T. Al-Goul, Eslam B. Elkaeed, Imen Zghab, Amira L. Shafik
Summary: Molecularly imprinted microparticles made from hydrazidine-cellulose biopolymer were developed for the preferential uptake of S-FP and chiral resolution of (+/-)-FP.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Multidisciplinary
Shuxin Xu, Lisheng Wang, Zhen Liu
Summary: Molecularly imprinted polymers (MIPs) are tailor-made affinity materials with unique binding cavities, which have been engineered for cancer therapy. Using nanoMIPs as alternatives to current nanomaterials offers potential solutions to existing challenges in biological ligand-based nanomedicines.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Polymer Science
Ian A. Nicholls, Kerstin Golker, Gustaf D. Olsson, Subramanian Suriyanarayanan, Jesper G. Wiklander
Summary: In recent years, there has been a significant increase in the use of theoretical and computational approaches in the study and development of molecular imprinting systems. These tools are utilized to enhance understanding of the mechanisms underlying the function of molecular imprinting systems or for designing new systems.
Article
Polymer Science
Yaohui Wang, Long Li, Gege Cheng, Lanfu Li, Xiuyu Liu, Qin Huang
Summary: A molecularly imprinted nanofiber membrane (MINM) with good adsorption performance for chrysin was prepared using electrospinning, showing potential for the adsorption and separation of active components in natural products.
Article
Chemistry, Analytical
Xu Ni, Xue Tang, Dan Wang, Jingjing Zhang, Linjie Zhao, Jie Gao, Pierre Dramou, Hua He
Summary: Molecularly imprinted polymers (MIPs) have shown remarkable impact in biomimetic recognition due to their high affinity and specificity. By combining MIPs with other analytical technologies, rapid extraction and sensitive detection of target compounds can be achieved, improving the level of analysis. The recognition mechanism and improvement of recognition elements, such as the addition of new nanomaterials, play important roles in enhancing the analytical performance of sensors, specifically in terms of selectivity. This review mainly focuses on the design strategies and applications of optical sensors, electrochemical sensors, and photoelectric sensors using molecular imprinting technology in various fields.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Materials Science, Multidisciplinary
Federica Pessagno, Matthew Blair, Mark J. Muldoon, Panagiotis Manesiotis
Summary: In this study, organocatalyst-selective molecularly imprinted polymers were successfully prepared using strong binding affinity. These polymers demonstrated exceptional binding for the organocatalyst targets and were able to reversibly capture the desired compounds from reaction mixtures. Rapid and straightforward solid-phase extraction protocols allowed for efficient catalyst recovery and reuse.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Biophysics
Danyang Zhao, Yao Zhang, Shaowei Ji, Yao Lu, Xinyu Bai, Mengting Yin, Chusen Huang, Nengqin Jia
Summary: The proposed highly sensitive quenching molecular imprinting photoelectrochemical sensor demonstrates efficient detection of acrylamide with excellent specificity, sensitivity, and stability, making it suitable for monitoring potential risks in food samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Chemistry, Analytical
Myriam Diaz-Alvarez, Esther Turiel, Antonio Martin-Esteban
Summary: Molecular imprinting technology is a established technique for tailor-made polymers with predetermined selectivity, which are considered excellent materials for sample preparation. However, there are some shortcomings in the use of molecularly imprinted polymers in sample preparation, such as binding sites heterogeneity and slow diffusion mass transfer. This review provides an overview of recent advances and trends in molecularly imprinted polymers-based extraction, with a focus on strategies to improve mass transfer and selective recognition in aqueous media, as well as a green perspective on the preparation of molecularly imprinted polymers.
JOURNAL OF SEPARATION SCIENCE
(2023)
Review
Polymer Science
Semra Akgonullu, Seckin Kilic, Cem Esen, Adil Denizli
Summary: The accurate detection of biological substances such as proteins has always been a hot topic in scientific research. Biomimetic sensors seek to imitate sensitive and selective mechanisms of biological systems and integrate these traits into applicable sensing platforms. Molecular imprinting technology has been extensively practiced in many domains, producing molecular recognition materials with specific capabilities. Molecularly imprinted polymers (MIPs), also known as plastic antibodies, are artificial receptors with high-affinity binding sites for a particular molecule or compound. MIPs for protein recognition are expected to have high affinity through interactions between polymer matrices and functional groups of the target protein. This critical review discusses recent advances in the synthesis, characterization, and application of MIP-based sensor platforms for protein detection.
Review
Chemistry, Analytical
Weiyingxue Yang, Yaxing Ma, Hui Sun, Chuixiu Huang, Xiantao Shen
Summary: Molecularly imprinted polymers (MIPs) based optical fiber (OF) sensors are gaining attention worldwide due to their high specificity and flexible sensing ability. The design of efficient MIPs based OF sensors has become a timely research topic, with advancements in simply combined MIP/OF sensors and directly integrated MIP@OF sensors. These sensors utilize MIPs as solid phase extraction materials and binding films, with emphasis on various detection methods such as fluorescence, surface plasmon resonance, and interferometry.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Ali Mandel Almusawy, Riyad H. Al-Anbari, Qusay F. Alsalhy, Arshed E. Al-Najar, Enrico Drioli
Summary: This study presents a novel membrane bioreactor that combines an electro bioreactor and moving biomedia to enhance biological treatment and reduce membrane fouling. The addition of zinc oxide nanoparticles (ZnO-NPs) decreases pore size and roughness while increasing permeate flux. The integration of biological, membrane, and electrochemical processes reduces membrane fouling. The system demonstrates significant improvement in retention capacity and maintains a stable flux during long-term operation.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Chemical
Jun Pan, Xianli Xu, Zhaohui Wang, Shi-Peng Sun, Zhaoliang Cui, Lassaad Gzara, Iqbal Ahmed, Omar Bamaga, Mohammed Albeirutty, Enrico Drioli
Summary: In this study, hydrophobic/hydrophilic PFPE/PVDF composite membranes were prepared by a method combining dip-coating and UV in situ polymerization for membrane distillation (MD) desalination. The composite membranes exhibited excellent anti-wetting properties and stable salt rejection, with higher MD flux. The study provided a simple and effective alternative for preparing hydrophobic composite membranes for MD applications.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Engineering, Chemical
Chen Wang, Myoung Jun Park, Dong Han Seo, Sherub Phuntsho, Ralph Rolly Gonzales, Hideto Matsuyama, Enrico Drioli, Ho Kyong Shon
Summary: This study explores the use of inkjet printing to fabricate polyelectrolyte multilayer membranes for organic solvent nanofiltration. The membranes showed enhanced stability and performance with the incorporation of single-walled carbon nanotubes. The best performing membrane (PEI/PSS-CNT)(10) exhibited stable performance and high permeances for various solvents.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Engineering, Chemical
Catia Algieri, Enrico Drioli
Summary: Membrane-based technology is attracting attention due to its low energy consumption, mild operating conditions, and high efficiency. Polymeric membranes are widely used for their low cost and reproducible preparation, but face issues like fouling and trade-off between permeability and selectivity. Inorganic membranes like zeolite membranes, with their hydrophilic nature, high stability, permeability, and selectivity, offer solutions to these problems. Their molecular-level pore size and adsorption property make them suitable for a variety of separation processes, although challenges like reproducibility, defects, and high manufacturing costs still hinder their industrial-scale application.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Simona Salerno, Enrico Drioli, Loredana De Bartolo
Article
Engineering, Chemical
Myoung Jun Park, Chen Wang, Ralph Rolly Gonzales, Sherub Phuntsho, Hideto Matsuyama, Enrico Drioli, Ho Kyong Shon
Summary: This study demonstrates the fabrication of waste-free thin film composite polyamide membranes using inkjet printing, which shows higher performance compared to traditional methods.
Article
Engineering, Chemical
S. Capizzano, M. Frappa, E. Drioli, F. Alessandro, F. Macedonio
Summary: Lithium, a reactive alkali metal, is widely used in electronics, medicine, and optics due to its high reactivity. The demand for lithium is continuously increasing, especially in the lithium-ion battery industry for electric vehicles and energy storage systems. This study demonstrates that polyvinylidene fluoride (PVDF) membranes cannot form LiCl crystals due to the chemical interaction between lithium and the PVDF matrix. Experimental evidence and various analyses show the modification of the PVDF membrane in contact with a lithium-containing solution.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Review
Chemistry, Applied
Alessandra Criscuoli, Omar Bamaga, Qian Wang, Zhaoliang Cui, Akram Nahri, Mohammed Albeirutty, Wanqin Jin, Enrico Drioli
Summary: Membrane bioreactors (MBRs) are currently the best available technology for municipal and wastewater treatment, but further improvements are needed. Coupling MBRs with high-retention membrane processes may be a solution. This paper presents the main features and commercial development of MBRs, discusses their performance when coupled with reverse osmosis (RO) and membrane distillation (MD) units, and emphasizes the limitations and further research needed for large-scale implementation.
SEPARATION AND PURIFICATION REVIEWS
(2023)
Article
Biophysics
Antonella Piscioneri, Sabrina Morelli, Tiziana Ritacco, Michele Giocondo, Rafael Penaloza, Enrico Drioli, Loredana De Bartolo
Summary: Biomaterial surface modification through the introduction of defined patterns of topography helps study cell behavior in response to geometrical cues. The lithographic molding technique is widely used for conferring biomaterial surface cues and enhancing the performance of biomedical devices. Different topographical features, such as channels, pillars, and pits, were investigated for their effects on different cell types, revealing distinct cell responses and interactions.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Mamdouh S. Alharthi, Omar Bamaga, Hani Abulkhair, Husam Organji, Amer Shaiban, Francesca Macedonio, Alessandra Criscuoli, Enrico Drioli, Zhaohui Wang, Zhaoliang Cui, Wanqin Jin, Mohammed Albeirutty
Summary: In this study, the integrated MBBR/MBR/DCMD process showed better removal efficiency of TDS and higher effluent permeate flux compared to the two-step MBR/DCMD process. The proposed membrane processes also outperformed the Jeddah Industrial Wastewater Treatment Plant in terms of effluent quality.
Article
Engineering, Chemical
Chen Wang, Myoung Jun Park, Ralph Rolly Gonzales, Hideto Matsuyama, Enrico Drioli, Ho Kyong Shon
Summary: The study presented the preparation of cross-linked multilayer PEI/GO nanofiltration membrane using inkjet printing assisted layer-by-layer assembly. The (PEI/GO)3 membrane showed the optimal separation performances with high permeability and selectivity. The membrane exhibited excellent rejection rates for different dyes and selectivity for different salts. Furthermore, (PEI/GO)3 membrane demonstrated desirable stability and long-term filtration stability.
Article
Biochemistry & Molecular Biology
Fangli Zhang, Wei Hou, Zhonglin Yang, Zhaohui Wang, Rizhi Chen, Enrico Drioli, Xiaozu Wang, Zhaoliang Cui
Summary: This paper proposed a membrane distillation and crystallization (MDCr) process to achieve zero liquid discharge of aniline wastewater. The effects of feed solution temperature and flow rate on the membrane distillation (MD) process were investigated. The results showed that under certain feeding conditions, the MD process had a high flux and salt rejection. The possibility of realizing zero liquid discharge of aniline wastewater in the MDCr process was verified.
Review
Biochemistry & Molecular Biology
Francesca Alessandro, Francesca Macedonio, Enrico Drioli
Summary: Water scarcity is a major concern for human sustainability and ecosystem preservation. Seawater desalination, particularly membrane distillation, has emerged as a sustainable solution. However, temperature polarization in membrane distillation leads to a significant reduction in water flux. Plasmonic nanostructures in membranes and the efficient conversion of light into heat offer potential prospects for enhancing solar-driven membrane distillation.
Article
Engineering, Chemical
Yanyan Ye, Tongyu Li, Yanmei Zhao, Junkuo Liu, Dongwei Lu, Jianqiang Wang, Kai Wang, Yingjie Zhang, Jun Ma, Enrico Drioli, Xiquan Cheng
Summary: In this study, we developed a facile approach to fabricate superhydrophobic polylactic acid (PLA) nanofiber membranes through coaxial electrospinning technology. By incorporating fluorine modified SiO2 clusters and polydimethylsiloxane coatings, the resulting membranes exhibited excellent hydrophobic properties and efficient water droplet removal.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Francesca Alessandro, Francesca Macedonio, Enrico Drioli
Summary: In recent decades, membrane-based processes have been widely used in various industrial processes. Membrane distillation, a thermally driven separation process, allows only vapor molecules to transfer through a microporous hydrophobic membrane. Wetting and temperature polarization negatively affect the performance of membrane distillation, but advanced membranes have been developed to overcome these issues. This review focuses on the basic concepts, membrane properties, and advances in membrane materials associated with membrane distillation. It also discusses the use of photothermal materials for solar-driven membrane distillation applications.
CHEMISTRY-SWITZERLAND
(2023)