NBR1 enables autophagy-dependent focal adhesion turnover

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

(2014) Zhenzhen Zhan et al.   Autophagy

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

(2014) William E. Dowdle et al.   NATURE CELL BIOLOGY

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

(2014) Samantha J. Stehbens et al.   NATURE CELL BIOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy-Dependent Production of Secreted Factors Facilitates Oncogenic RAS-Driven Invasion

(2014) R. Lock et al.   Cancer Discovery

E3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics

(2014) Shishan Deng et al.   Cell Adhesion & Migration

Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site

(2013) Ikuko Koyama-Honda et al.   Autophagy

Autophagy modulates cell migration and β1 integrin membrane recycling

(2013) Véronique Tuloup-Minguez et al.   CELL CYCLE

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Dynamic Regulation of the Structure and Functions of Integrin Adhesions

(2013) Haguy Wolfenson et al.   DEVELOPMENTAL CELL

Mechanosensitivity and compositional dynamics of cell–matrix adhesions

(2013) Herbert B Schiller et al.   EMBO REPORTS

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Opening the floodgates: proteomics and the integrin adhesome

(2012) Tamar Geiger et al.   CURRENT OPINION IN CELL BIOLOGY

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells

(2012) S Galavotti et al.   ONCOGENE

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Calpain-mediated Proteolysis of Paxillin Negatively Regulates Focal Adhesion Dynamics and Cell Migration

(2011) Christa L. Cortesio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

(2011) Eisuke Itakura et al.   JOURNAL OF CELL BIOLOGY

MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin

(2011) F. Shi et al.   JOURNAL OF CELL SCIENCE

Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity

(2011) Tse-Chun Kuo et al.   NATURE CELL BIOLOGY

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)

(2010) Keefe T. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

P130Cas Src-Binding and Substrate Domains Have Distinct Roles in Sustaining Focal Adhesion Disassembly and Promoting Cell Migration

(2010) Leslie M. Meenderink et al.   PLoS One

Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover

(2009) Sarah Waters et al.   FEBS LETTERS

Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

(2009) Wei-Ting Chao et al.   FEBS LETTERS

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells

(2009) Ellen J. Ezratty et al.   JOURNAL OF CELL BIOLOGY

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Effect of Ablation or Inhibition of Stromal Matrix Metalloproteinase-9 on Lung Metastasis in a Breast Cancer Model Is Dependent on Genetic Background

(2008) M. D. Martin et al.   CANCER RESEARCH

Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer

(2008) Bryan E. Welm et al.   Cell Stem Cell

Midbody ring disposal by autophagy is a post-abscission event of cytokinesis

(2008) Christian Pohl et al.   NATURE CELL BIOLOGY

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL