Chromatin assembly: Journey to the CENter of the chromosome

No longer a nuisance: long non-coding RNAs join CENP-A in epigenetic centromere regulation

(2016) Silvana Rošić et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation

(2016) Jun-ichirou Ohzeki et al.   DEVELOPMENTAL CELL

Co-evolving CENP-A and CAL1 Domains Mediate Centromeric CENP-A Deposition across Drosophila Species

(2016) Leah Rosin et al.   DEVELOPMENTAL CELL

Centromere localization and function of Mis18 requires Yippee‐like domain‐mediated oligomerization

(2016) Lakxmi Subramanian et al.   EMBO REPORTS

Licensing of Centromeric Chromatin Assembly through the Mis18α-Mis18β Heterotetramer

(2016) Isaac K. Nardi et al.   MOLECULAR CELL

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

(2016) Antoine Aze et al.   NATURE CELL BIOLOGY

CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres

(2016) Samantha J Falk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

(2016) Hsiao P.J. Voon et al.   NUCLEIC ACIDS RESEARCH

Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres

(2016) Justyne E. Ross et al.   Epigenetics & Chromatin

CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres

(2016) Samantha J Falk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Centromeric Transcription Regulates Aurora-B Localization and Activation

(2016) Michael D. Blower   Cell Reports

Establishment of Centromeric Chromatin by the CENP-A Assembly Factor CAL1 Requires FACT-Mediated Transcription

(2015) Chin-Chi Chen et al.   DEVELOPMENTAL CELL

Dynamic Phosphorylation of CENP-A at Ser68 Orchestrates Its Cell-Cycle-Dependent Deposition at Centromeres

(2015) Zhouliang Yu et al.   DEVELOPMENTAL CELL

The molecular basis for centromere identity and function

(2015) Kara L. McKinley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stable complex formation of CENP-B with the CENP-A nucleosome

(2015) Risa Fujita et al.   NUCLEIC ACIDS RESEARCH

CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

(2015) S. J. Falk et al.   SCIENCE

Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex

(2015) M Daniel Ricketts et al.   Nature Communications

Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin

(2015) Sandra Catania et al.   PLoS Genetics

Polo-like Kinase 1 Licenses CENP-A Deposition at Centromeres

(2014) Kara L. McKinley et al.   CELL

The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic localization of CENP-A

(2014) Gary M.R. Deyter et al.   GENES & DEVELOPMENT

CAL1 is theDrosophilaCENP-A assembly factor

(2014) Chin-Chi Chen et al.   JOURNAL OF CELL BIOLOGY

Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division

(2014) Silvana Rošić et al.   JOURNAL OF CELL BIOLOGY

The quantitative architecture of centromeric chromatin

(2014) Dani L Bodor et al.   eLife

A long non-coding RNA is required for targeting centromeric protein A to the human centromere

(2014) Delphine Quénet et al.   eLife

The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo

(2014) Steven Henikoff et al.   eLife

Hypermorphic expression of centromeric retroelement-encoded small RNAs impairs CENP-A loading

(2013) Dawn M. Carone et al.   CHROMOSOME RESEARCH

Octameric CENP-A Nucleosomes Are Present at Human Centromeres throughout the Cell Cycle

(2013) Abbas Padeganeh et al.   CURRENT BIOLOGY

Dimerization of the CENP-A assembly factor HJURP is required for centromeric nucleosome deposition

(2013) Ewelina Zasadzińska et al.   EMBO JOURNAL

WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition

(2013) Naoyuki Sarai et al.   EMBO JOURNAL

SCFSlimbubiquitin ligase suppresses condensin II–mediated nuclear reorganization by degrading Cap-H2

(2013) Daniel W. Buster et al.   JOURNAL OF CELL BIOLOGY

Distinct modes of centromere protein dynamics during cell cycle progression in Drosophila S2R+ cells

(2013) P. V. Lidsky et al.   JOURNAL OF CELL SCIENCE

Assembly in G1 phase and long-term stability are unique intrinsic features of CENP-A nucleosomes

(2013) Dani L. Bodor et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of histone H2A–H2B recognition by the essential chaperone FACT

(2013) Maria Hondele et al.   NATURE

A two-step mechanism for epigenetic specification of centromere identity and function

(2013) Daniele Fachinetti et al.   NATURE CELL BIOLOGY

Solo or doppio: how many CENP-As make a centromeric nucleosome?

(2013) Elaine M Dunleavy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CENP-A confers a reduction in height on octameric nucleosomes

(2013) Matthew D D Miell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The octamer is the major form of CENP-A nucleosomes at human centromeres

(2013) Dan Hasson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phylogeny as the basis for naming histones

(2013) Paul B. Talbert et al.   TRENDS IN GENETICS

Eukaryotic Replisome Components Cooperate to Process Histones During Chromosome Replication

(2013) Magdalena Foltman et al.   Cell Reports

The CENP-A nucleosome

(2013) Minh Bui et al.   Nucleus

Catch me if you can

(2013) Maria Hondele et al.   Nucleus

RNA as a Structural and Regulatory Component of the Centromere

(2012) Jonathan I. Gent et al.   Annual Review of Genetics

Cell-Cycle-Dependent Structural Transitions in the Human CENP-A Nucleosome In Vivo

(2012) Minh Bui et al.   CELL

The unconventional structure of centromeric nucleosomes

(2012) Steven Henikoff et al.   CHROMOSOMA

CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly

(2012) Valérie De Rop et al.   CHROMOSOMA

Evolutionary insights into the role of the essential centromere protein CAL1 in Drosophila

(2012) Ragini Phansalkar et al.   CHROMOSOME RESEARCH

Temporal control of epigenetic centromere specification

(2012) Luis P. Valente et al.   CHROMOSOME RESEARCH

Pericentric and centromeric transcription: a perfect balance required

(2012) Laura E. Hall et al.   CHROMOSOME RESEARCH

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

(2012) Simon J. Elsässer et al.   NATURE

Transcription in the maintenance of centromere chromatin identity

(2012) F. L. Chan et al.   NUCLEIC ACIDS RESEARCH

Active transcription and essential role of RNA polymerase II at the centromere during mitosis

(2012) F. L. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cell Cycle Timing of Centromeric Chromatin Assembly in Drosophila Meiosis Is Distinct from Mitosis Yet Requires CAL1 and CENP-C

(2012) Elaine M. Dunleavy et al.   PLOS BIOLOGY

Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-ACnp1 in Fission Yeast

(2012) Eun Shik Choi et al.   PLoS Genetics

CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin

(2012) Silvia Dambacher et al.   Nucleus

Epigenetic Centromere Propagation and the Nature of CENP-A Nucleosomes

(2011) Ben E. Black et al.   CELL

The F Box Protein Partner of Paired Regulates Stability of Drosophila Centromeric Histone H3, CenH3CID

(2011) Olga Moreno-Moreno et al.   CURRENT BIOLOGY

Endogenous Transcription at the Centromere Facilitates Centromere Activity in Budding Yeast

(2011) Kentaro Ohkuni et al.   CURRENT BIOLOGY

Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression

(2011) Mariana C.C. Silva et al.   DEVELOPMENTAL CELL

Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP

(2011) H. Hu et al.   GENES & DEVELOPMENT

Identification of Noncoding Transcripts from within CENP-A Chromatin at Fission Yeast Centromeres

(2011) Eun Shik Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly

(2011) Ben Moree et al.   JOURNAL OF CELL BIOLOGY

HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore

(2011) Meghan C. Barnhart et al.   JOURNAL OF CELL BIOLOGY

XenopusHJURP and condensin II are required for CENP-A assembly

(2011) Rafael Bernad et al.   JOURNAL OF CELL BIOLOGY

Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity

(2011) Dominique Ray-Gallet et al.   MOLECULAR CELL

In vitro centromere and kinetochore assembly on defined chromatin templates

(2011) Annika Guse et al.   NATURE

Crystal structure of the human centromeric nucleosome containing CENP-A

(2011) Hiroaki Tachiwana et al.   NATURE

Structure of the budding yeast Saccharomyces cerevisiae centromeric histones Cse4-H4 complexed with the chaperone Scm3

(2011) H. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of the centromere-specific histone Cse4 by the chaperone Scm3

(2011) U.-S. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila CENH3 Is Sufficient for Centromere Formation

(2011) M. J. Mendiburo et al.   SCIENCE

Assembly of Drosophila Centromeric Chromatin Proteins during Mitosis

(2011) Barbara G. Mellone et al.   PLoS Genetics

H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G1phase

(2011) Elaine M. Dunleavy et al.   Nucleus

Chaperoning Histones during DNA Replication and Repair

(2010) Monica Ransom et al.   CELL

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

(2010) Jan H Bergmann et al.   EMBO JOURNAL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

(2010) Peter V. Kharchenko et al.   NATURE

A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A

(2010) Anaïck Lagana et al.   NATURE CELL BIOLOGY

Dynamics of a novel centromeric histone variant CenH3 reveals the evolutionary ancestral timing of centromere biogenesis

(2010) Manu Dubin et al.   NUCLEIC ACIDS RESEARCH

CenH3/CID Incorporation Is Not Dependent on the Chromatin Assembly Factor CHD1 in Drosophila

(2010) Valerie Podhraski et al.   PLoS One

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres

(2010) M. Shuaib et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A super-resolution map of the vertebrate kinetochore

(2010) S. A. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Ancestry of the CENP-A Chaperones Scm3 and HJURP

(2009) Luis Sanchez-Pulido et al.   CELL

HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres

(2009) Elaine M. Dunleavy et al.   CELL

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

(2009) Daniel R. Foltz et al.   CELL

Active establishment of centromeric CENP-A chromatin by RSF complex

(2009) Marinela Perpelescu et al.   JOURNAL OF CELL BIOLOGY

CENP-H–containing Complex Facilitates Centromere Deposition of CENP-A in Cooperation with FACT and CHD1

(2009) Masahiro Okada et al.   MOLECULAR BIOLOGY OF THE CELL

CENPA overexpression promotes genome instability in pRb-depleted human cells

(2009) Angela Amato et al.   Molecular Cancer

Fission Yeast Scm3: A CENP-A Receptor Required for Integrity of Subkinetochore Chromatin

(2009) Alison L. Pidoux et al.   MOLECULAR CELL

Non-coding murine centromeric transcripts associate with and potentiate Aurora B kinase

(2009) Federica Ferri et al.   NUCLEIC ACIDS RESEARCH

Structure of an RNA Polymerase II-TFIIB Complex and the Transcription Initiation Mechanism

(2009) X. Liu et al.   SCIENCE

LINE Retrotransposon RNA Is an Essential Structural and Functional Epigenetic Component of a Core Neocentromeric Chromatin

(2009) Anderly C. Chueh et al.   PLoS Genetics

Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagation

(2008) Sylvia Erhardt et al.   JOURNAL OF CELL BIOLOGY

Dynamics of inner kinetochore assembly and maintenance in living cells

(2008) Peter Hemmerich et al.   JOURNAL OF CELL BIOLOGY