Identification of novel γ-globin inducers among all potential erythroid druggable targets

An erythroid to myeloid cell fate conversion is elicited by LSD1 inactivation

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UNC0638 induces high levels of fetal hemoglobin expression in β-thalassemia/HbE erythroid progenitor cells

(2020) Tiwaporn Nualkaew et al.   ANNALS OF HEMATOLOGY

The ER cargo receptor SURF4 facilitates efficient erythropoietin secretion

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Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding

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Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells

(2018) Jeremy D. Grevet et al.   SCIENCE

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

(2018) Lei Yu et al.   GENES & DEVELOPMENT

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

(2017) Julia Joung et al.   Nature Protocols

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression

(2015) A. Renneville et al.   BLOOD

Global transcriptome analyses of human and murine terminal erythroid differentiation

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Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood

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Cardiovascular Function and Treatment in β-Thalassemia Major

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Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

(2013) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thalassaemia

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VHL and HIF signalling in renal cell carcinogenesis

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The cost of health care for children and adults with sickle cell disease

(2009) Teresa L. Kauf et al.   AMERICAN JOURNAL OF HEMATOLOGY