Nonsynonymous C1653T Mutation of Hepatitis B Virus X Gene Enhances Malignancy of Hepatocellular Carcinoma Cells

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Role for calcium‐activated potassium channels (BK) in migration control of human hepatocellular carcinoma cells

(2021) Yuan He et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response

(2021) Fang Yu et al.   NUCLEIC ACIDS RESEARCH

Effectiveness and Safety of Apatinib Plus Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer

(2021) Jian-Xian Lin et al.   JAMA Network Open

Anti–PD-1/PD-L1 Blockade Immunotherapy Employed in Treating Hepatitis B Virus Infection–Related Advanced Hepatocellular Carcinoma: A Literature Review

(2020) Bin Li et al.   Frontiers in Immunology

ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis

(2020) Haina Xie et al.   Molecular Therapy-Nucleic Acids

MCUR1 facilitates epithelial-mesenchymal transition and metastasis via the mitochondrial calcium dependent ROS/Nrf2/Notch pathway in hepatocellular carcinoma

(2019) Mingpeng Jin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma

(2019) Jacopo Baglieri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The HBx–CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1

(2019) Yajun Li et al.   Cell Death & Disease

A global view of hepatocellular carcinoma: trends, risk, prevention and management

(2019) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

GPR43 regulates HBV X protein (HBx)-induced inflammatory response in human LO2 hepatocytes

(2019) Tao He et al.   BIOMEDICINE & PHARMACOTHERAPY

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

(2018) Nobuaki Takahashi et al.   CANCER CELL

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem cells through activating PI3K/AKT signal pathway

(2017) Mingyue Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer

(2017) Yi Lin et al.   Oncotarget

A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines

(2016) Ying Shi et al.   CANCER LETTERS

Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes

(2016) Geoffrey J. Markowitz et al.   CANCER RESEARCH

Acteoside-mediates chemoprevention of experimental liver carcinogenesis through STAT-3 regulated oxidative stress and apoptosis

(2016) Kaiser J. Peerzada et al.   ENVIRONMENTAL TOXICOLOGY

FGFR3 promotes angiogenesis-dependent metastasis of hepatocellular carcinoma via facilitating MCP-1-mediated vascular formation

(2016) Xinyu Liu et al.   MEDICAL ONCOLOGY

Plasma membrane calcium channels in cancer: Alterations and consequences for cell proliferation and migration

(2015) Nadine Déliot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma

(2015) Xiaoguang Li et al.   GUT

EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2015) et al.   JOURNAL OF HEPATOLOGY

Endothelial progenitors promote hepatocarcinoma intrahepatic metastasis through monocyte chemotactic protein-1 induction of microRNA-21

(2014) Yu-Tsung Shih et al.   GUT

The Hepatitis B Virus (HBV) HBx Protein Activates AKT To Simultaneously Regulate HBV Replication and Hepatocyte Survival

(2014) Siddhartha Rawat et al.   JOURNAL OF VIROLOGY

X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma

(2014) Ying Xie et al.   TUMOR BIOLOGY

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Inhibitory effects of blockage of intermediate conductance Ca2+-activated K+ channels on proliferation of hepatocellular carcinoma cells

(2013) Xiao-wei Yang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans

(2012) X. Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro

(2011) G Wu et al.   BRITISH JOURNAL OF CANCER

Involvement of the NF-κB pathway in multidrug resistance induced by HBx in a hepatoma cell line

(2011) Y. Liu et al.   JOURNAL OF VIRAL HEPATITIS

Tumor suppressor protein p53 induces degradation of the oncogenic protein HBx

(2009) Sung Gyoo Park et al.   CANCER LETTERS

Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16INK4a expression via DNA methylation

(2009) Ye-Jin Kim et al.   CANCER LETTERS

Sequential accumulation of the mutations in core promoter of hepatitis B virus is associated with the development of hepatocellular carcinoma in Qidong, China

(2008) Xia Guo et al.   JOURNAL OF HEPATOLOGY

Associations Between Hepatitis B Virus Genotype and Mutants and the Risk of Hepatocellular Carcinoma

(2008) H.-I. Yang et al.   JNCI-Journal of the National Cancer Institute

Identification of functionally important amino acid residues in the mitochondria targeting sequence of Hepatitis B virus X protein

(2008) Sai Kam Li et al.   VIROLOGY