Berberine Pretreatment Confers Cardioprotection Against Ischemia–Reperfusion Injury in a Rat Model of Type 2 Diabetes

Oxidative stress induces phosphorylation of neuronal NOS in cardiomyocytes through AMP-activated protein kinase (AMPK)

(2015) Rekha Kar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension

(2015) Jiarong Lan et al.   JOURNAL OF ETHNOPHARMACOLOGY

A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine

(2015) Shenghua Gu et al.   Molecular BioSystems

Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K–Akt signaling in diabetic rats

(2014) Keke Chen et al.   APOPTOSIS

Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy

(2014) Ming-Hui Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of interplay between autophagy and apoptosis in the diabetic heart

(2013) Ming-Hui Zou et al.   Autophagy

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

(2013) Wenjun Yan et al.   BASIC RESEARCH IN CARDIOLOGY

Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice

(2013) Karina Huynh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Berberine Ameliorates Cold and Mechanical Allodynia in a Rat Model of Diabetic Neuropathy

(2013) Si Oh Kim et al.   JOURNAL OF MEDICINAL FOOD

Berberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase

(2013) Wenguang Chang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Berberine Attenuates Ischemia-Reperfusion Injury Via Regulation of Adenosine-5′-monophosphate Kinase Activity in Both Non-ischemic and Ischemic Areas of the Rat Heart

(2012) Wenguang Chang et al.   CARDIOVASCULAR DRUGS AND THERAPY

Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats

(2012) Hamid Kalalian-Moghaddam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sevoflurane Confers Additive Cardioprotection to Ethanol Preconditioning Associated With Enhanced Phosphorylation of Glycogen Synthase Kinase-3β and Inhibition of Mitochondrial Permeability Transition Pore Opening

(2012) Anna Onishi et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis

(2012) Ming Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ameliorative effect of berberine on renal damage in rats with diabetes induced by high-fat diet and streptozotocin

(2012) Duo Wu et al.   PHYTOMEDICINE

Berberine ameliorates hyperglycemia in alloxan-induced diabetic C57BL/6 mice through activation of Akt signaling pathway

(2011) Xi Xie et al.   ENDOCRINE JOURNAL

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis

(2011) J. L. Sartoretto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin Prevents Progression of Heart Failure in Dogs

(2009) Hideyuki Sasaki et al.   CIRCULATION

Distinct Early Signaling Events Resulting From the Expression of the PRKAG2 R302Q Mutant of AMPK Contribute to Increased Myocardial Glycogen

(2009) Karalyn D. Folmes et al.   Circulation-Cardiovascular Genetics

Rosiglitazone-induced myocardial protection against ischaemia-reperfusion injury is mediated via a phosphatidylinositol 3-kinase/Akt-dependent pathway

(2009) Xue-Jiao Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin

(2009) Chunmei Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Characterization of High-Fat Diet and Multiple Low-Dose Streptozotocin Induced Type 2 Diabetes Rat Model

(2009) Ming Zhang et al.   Experimental Diabetes Research

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

(2009) Hao Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

AMP-activated protein kinase control of energy metabolism in the ischemic heart

(2008) G D Lopaschuk   INTERNATIONAL JOURNAL OF OBESITY

Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine

(2008) Yifei Zhang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combination of simvastatin with berberine improves the lipid-lowering efficacy

(2008) Wei-Jia Kong et al.   METABOLISM-CLINICAL AND EXPERIMENTAL