Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice

Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial

(2016) Barry Greenberg et al.   LANCET

Adeno-associated virus-mediated gene therapy in cardiovascular disease

(2015) Nadjib Hammoudi et al.   CURRENT OPINION IN CARDIOLOGY

Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy

(2014) Bianca C. Bernardo et al.   FASEB JOURNAL

Inhibition of MicroRNA-92a Protects Against Ischemia/Reperfusion Injury in a Large-Animal Model

(2013) Rabea Hinkel et al.   CIRCULATION

Epidemiology of Heart Failure

(2013) Véronique L. Roger   CIRCULATION RESEARCH

Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure

(2013) Krisztina Zsebo et al.   CIRCULATION RESEARCH

Targeting Sarcoplasmic Reticulum Calcium ATPase by Gene Therapy

(2013) Judith K. Gwathmey et al.   HUMAN GENE THERAPY

2013 ACCF/AHA Guideline for the Management of Heart Failure

(2013) Clyde W. Yancy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Prospects for nucleic acid-based therapeutics against hepatitis C virus

(2013) Chang Ho Lee   WORLD JOURNAL OF GASTROENTEROLOGY

Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart

(2012) Masanori Obana et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

(2012) Evangelia G. Kranias et al.   CIRCULATION RESEARCH

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)

(2011) Mariell Jessup et al.   CIRCULATION

Nucleic Acid-based Technologies in Therapy of Malignant Gliomas

(2011) Monika Piwecka et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

(2010) Rakesh N. Veedu et al.   CHEMISTRY & BIODIVERSITY

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Phospholamban Ablation Rescues Sarcoplasmic Reticulum Ca 2+ Handling but Exacerbates Cardiac Dysfunction in CaMKIIδ C Transgenic Mice

(2009) Tong Zhang et al.   CIRCULATION RESEARCH

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

(2009) Haiyun Ling et al.   JOURNAL OF CLINICAL INVESTIGATION

β-Adrenergic receptor signaling in the heart: Role of CaMKII

(2009) Michael Grimm et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The   isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

(2009) J. Backs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic gene silencing strategies for polyglutamine disorders

(2009) Janine Scholefield et al.   TRENDS IN GENETICS

Rescue of Ca2+ overload-induced left ventriclur dysfunction by targeted ablation of phospholamban

(2008) Tsuyoshi Tsuji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reversing Advanced Heart Failure by Targeting Ca2+ Cycling

(2008) David M. Kaye et al.   Annual Review of Medicine

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology