Article
Psychology, Developmental
Sally H. Adams, Jason P. Schaub, Jason M. Nagata, M. Jane Park, Claire D. Brindis, Charles E. Irwin
Summary: Based on the March 2021 data, most unvaccinated young adults in the US express an intention to receive COVID-19 vaccines, but 24% remain hesitant. Common reasons for hesitancy include concerns about vaccine safety and side effects, as well as the belief that others are in greater need of the vaccine.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Bijaya Kumar Padhi, Venkatesan Chakrapani, Madhu Gupta, Nikita Sharma, Binod Kumar Patro, Sitanshu Sekhar Kar, Ritesh Singh, Star Pala, Lalit Sankhe, Bhavesh Modi, Surya Bali, Neeti Rustagi, Lovely Jain, Jatina Vij, Prakasini Satapathy, Kapil Goel, Vineeth Rajagopal, Tanvi Kiran, Arun Kumar Aggarwal
Summary: The willingness to receive COVID-19 vaccines among healthcare workers in India increased over time as the severity of the pandemic increased. Factors such as trust in the healthcare system, confidence in domestic vaccines, and perceived risk of contracting COVID-19 were found to be associated with the willingness to receive vaccines. Being married and having a high socio-economic status were also significant factors.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Immunology
Eman Ibrahim Alfageeh, Noor Alshareef, Khadijah Angawi, Fahad Alhazmi, Gowokani Chijere Chirwa
Summary: The study revealed that residents in the southern region, those who have received the seasonal influenza vaccine, believe in mandatory COVID-19 vaccination, and express high levels of concern about COVID-19 are more willing to get vaccinated. On the other hand, individuals with a history of vaccine refusal are less likely to have the intention to be vaccinated. There is a need for multifaceted interventions to target the low acceptance rate among the Saudi population, focusing on raising awareness and emphasizing the safety and efficacy of the COVID-19 vaccine.
Article
Immunology
Shihoko Kajiwara, Naomi Akiyama, Michio Ohta
Summary: This study aimed to analyze the intentions of women aged 15-49 years regarding the COVID-19 vaccination and identify methods of promoting vaccination. The results showed that the proportion of women who refused COVID-19 vaccination in Japan was 17.0%, with the most common reasons being safety and side effect concerns. Among those who received the second vaccination, 32.7% hesitated or refused the third vaccination due to side effect concerns, a lack of information, and the influence of their surroundings.
Article
Public, Environmental & Occupational Health
Lovely Jain, Jatina Vij, Prakasini Satapathy, Venkatesan Chakrapani, Binod Patro, Sitanshu Sekhar Kar, Ritesh Singh, Star Pala, Lalit Sankhe, Bhavesh Modi, Surya Bali, Neeti Rustagi, Vineeth Rajagopal, Tanvi Kiran, Kapil Goel, Arun Kumar Aggarwal, Madhu Gupta, Bijaya Kumar Padhi
Summary: The study found that Indian college students had relatively high levels of positive intentions to receive COVID-19 vaccines, although about one-third were not sure or unwilling to receive the vaccine, indicating possible vaccine hesitancy. Informational campaigns and other strategies to address vaccine hesitancy are needed to promote uptake of COVID-19 vaccines.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Immunology
Kirsten Barnes, Ben Colagiuri
Summary: This study compared the effects of positive and negative framing on COVID-19 vaccination intentions and found that positive framing was effective in increasing intentions for receiving less familiar vaccines. However, standard negative framing appeared to increase intentions for familiar vaccines. These findings provide important evidence for the use of positive framing to improve vaccine uptake for less familiar vaccines, but caution is needed when using positive framing for familiar vaccines.
Article
Public, Environmental & Occupational Health
Lara Steinmetz
Summary: This study aims to explore the sociodemographic predictors, main reasons, and the relationship between these reasons and sociodemographic characteristics of vaccine hesitancy during the COVID-19 pandemic. The findings indicate that younger age, lower education, lower household income, and being born outside of Norway are associated with higher levels of vaccine hesitancy. Different population groups have different determinants of vaccine hesitancy, highlighting the importance of clear public health communication.
Article
Immunology
Michael J. Cima, Donald McCormick, Austin Porter, Namvar Zohoori, Scott Alsbrook, Jose R. Romero
Summary: To assess the uptake of COVID-19 vaccines among public K-12 teachers and staff in Arkansas, the Arkansas Department of Health evaluated the vaccination status of 66,076 individuals using the state immunization registry. After 13 weeks of availability, 51.2% of teachers and staff had received at least one dose of vaccine, with lower uptake in rural areas. Vaccine hesitancy may be a contributing factor to the lower vaccination rates in certain factions of the teacher and staff population.
Article
Multidisciplinary Sciences
Hengchen Dai, Silvia Saccardo, Maria A. Han, Lily Roh, Naveen Raja, Sitaram Vangala, Hardikkumar Modi, Shital Pandya, Michael Sloyan, Daniel M. Croymans
Summary: Enhancing vaccine uptake is crucial for public health, and effective communication strategies are necessary to overcome vaccine hesitancy. This study conducted two randomized controlled trials to test the impact of behavioral interventions on COVID-19 vaccine uptake, showing that text-based reminders can significantly increase vaccination rates, especially when designed to give participants ownership over the vaccine.
Article
Public, Environmental & Occupational Health
Yue Su, Sijia Li, Jia Xue, Ang Li, Tingshao Zhu
Summary: This study aims to develop and validate a measurement tool for evaluating the importance of influencing factors related to COVID-19 vaccination intention in China and examine demographic differences. The study found that educational level may influence individuals' evaluation of the importance of factors.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Ann Marie R. Hess, Colin T. Waters, Elizabeth A. Jacobs, Kerri L. Barton, Kathleen M. Fairfield
Summary: This study aimed to identify factors associated with COVID-19 vaccine hesitancy, including sources of information. The results showed that younger individuals who had less trust in government information were more likely to be vaccine hesitant, but they sought advice from primary care physicians. They expressed concerns about vaccine efficacy, side effects, and the speed of vaccine development.
Article
Immunology
Rima Nath, Asif Imtiaz, Shobod Deba Nath, Emran Hasan
Summary: The study found that vaccine hesitancy is the most important factor affecting young adults' willingness to get the COVID-19 vaccine, while eHealth literacy is positively associated with vaccine uptake intention, and vaccine literacy is not significantly associated. To boost young adults' confidence in vaccines, it is crucial to communicate the latest vaccine safety updates through authentic channels.
Article
Immunology
Stefanie A. Joseph, Jean Gregory Jerome, Foday Boima, Pierre Ricard Pognon, Donald Fejfar, Yusupha Dibba, Daniel Lavalie, Mohamed Bailor Barrie, Aramide Oteju, Mohamed Sheku, Mariama Mahmoud, Jusu Mattia, Dale A. Barnhart
Summary: Sierra Leone, a West African country with a population of over 8 million, faces challenges in rural populations' access to and willingness to receive the COVID-19 vaccine. A cross-sectional study conducted in Ministry of Health and Sanitation facilities revealed that less than half of the patients/caregivers had the opportunity to be vaccinated, and 44% of the unvaccinated population would refuse a vaccine if offered at no cost. Lack of access and official education messaging are the main barriers to vaccine uptake in Sierra Leone.
Article
Immunology
Masaki Machida, Itaru Nakamura, Takako Kojima, Reiko Saito, Tomoki Nakaya, Tomoya Hanibuchi, Tomoko Takamiya, Yuko Odagiri, Noritoshi Fukushima, Hiroyuki Kikuchi, Shiho Amagasa, Hidehiro Watanabe, Shigeru Inoue
Summary: This study investigated the acceptance and hesitancy towards the COVID-19 vaccine in Japan, finding that 62.1% of participants were willing to get vaccinated. The research also revealed that vaccine acceptance was lower among women, adults aged 20-49 years, and those with a low-income level. Psychological factors, such as the perceived effectiveness of the vaccine and willingness to protect others, were identified as important factors associated with vaccine acceptance.
Article
Public, Environmental & Occupational Health
Terra Manca, Robin M. Humble, Laura Aylsworth, Eunah Cha, Sarah E. Wilson, Samantha B. Meyer, Devon Greyson, Manish Sadarangani, Jeanna Parsons Leigh, Shannon E. MacDonald
Summary: This study explored the motivations, perceptions, and concerns of Racialized minority and Indigenous Peoples regarding COVID-19 vaccination. The findings revealed that individuals' intention to receive the vaccine was associated with their perceptions of vaccine-related risks, symbolic associations of vaccines with hope, and intersecting social privileges and inequities.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Nursing
Wendy Pringle, Devon Greyson, Janice E. Graham, Robyn Berman, Eve Dube, Julie A. Bettinger
Summary: Confidence in both vaccination itself and vaccine knowledge and counseling skills is important for Canadian midwives to have effective discussions about vaccines with their clients. Vaccine hesitancy or counseling hesitancy may result in deferred or shortened vaccine discussions. Current clinical communication tools and techniques for addressing vaccine hesitancy do not always meet the needs of midwives supporting clients' informed choice decisions. Canadian midwives require more and clearer resources on the risks and benefits of vaccination in pregnancy.
BIRTH-ISSUES IN PERINATAL CARE
(2023)
Article
Immunology
Julie A. Bettinger, Michael A. Irvine, Hennady P. Shulha, Louis Valiquette, Matthew P. Muller, Otto G. Vanderkooi, James D. Kellner, Karina A. Top, Manish Sadarangani, Allison McGeer, Jennifer E. Isenor, Kimberly Marty, Phyumar Soe, Gaston De Serres
Summary: This study examined the short-term safety of COVID-19 vaccines in adults with a previous history of SARS-CoV-2 infection. It found that adults with moderate or severe previous infection were more likely to experience health events after each vaccine dose, while the risk associated with previous infection was attenuated after subsequent doses.
CLINICAL INFECTIOUS DISEASES
(2023)
Review
Obstetrics & Gynecology
Jia Tong Song, Mai-Lei Woo Kinshella, Kondwani Kawaza, David M. M. Goldfarb
Summary: This systematic review identified and analyzed evidence-based interventions to promote breastfeeding among preterm and low birth weight infants. The interventions found included education and breastfeeding support programs, early discharge, oral stimulation, artificial teats and cups, kangaroo mother care, and supportive policies within NICUs. All of these interventions were associated with increased rates of breastfeeding at discharge, with kangaroo mother care showing the highest increase.
BREASTFEEDING MEDICINE
(2023)
Article
Pediatrics
Alysha L. Deslippe, Olivia De-Jongh Gonzalez, E. Jean Buckler, Geoff D. C. Ball, Josephine Ho, Annick Bucholz, Katherine M. Morrison, Louise C. Masse
Summary: This study evaluated the impact of social support features and parent co-participation on the long-term use of the Aim2Be app among youth. The results indicated that the influence of social support features varied depending on age, emphasizing the importance of considering age in app design.
Article
Psychiatry
Sarah M. Hutchison, Ursula Brain, Ruth E. Grunau, Boris Kuzeljevic, Mike Irvine, Louise C. Masse, Tim F. Oberlander
Summary: Prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants is associated with increased internalising and anxious behaviours in young children, but it is unclear whether this association persists into early adolescence. Furthermore, the contribution of in utero SSRI exposure versus underlying maternal mood to these associations is not well established.
Article
Infectious Diseases
Chelsea Caya, Ameeta E. Singh, Bouchra Serhir, Veronique Morin, Michael D. Libman, Rachel Corsini, David M. Goldfarb, Tom Wong, Yiqing Xia, Mathieu Maheu-Giroux, Cedric P. Yansouni
Summary: In this study, the field diagnostic accuracy of a syphilis rapid test (RDT) using serum and whole blood was evaluated in two Canadian Arctic communities. The results showed that the RDT had good sensitivity and specificity for both whole blood and serum, making it suitable for rapid screening of individuals with syphilis infection in real-world settings.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Review
Clinical Neurology
Aurore Curie, Tim F. F. Oberlander, Karin B. Jensen
Summary: Placebo responses are frequently observed in research studies and clinical contexts, yet there is limited knowledge about the placebo effect among children with neurodevelopmental disorders. In this review, the authors discuss the placebo effect in autism spectrum disorder (ASD) and how it can be influenced by caregivers or clinicians indirectly shaping patient outcomes. Understanding placebo effects in ASD may help differentiate genuine treatment effects from contextual factors in clinical trials and improve research designs and treatments for ASD symptoms. Furthermore, deeper knowledge about placebo and nocebo effects may optimize care delivery for individuals with ASD in the future.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Behavioral Sciences
Katelynn E. Boerner, Leora Pearl-Dowler, Liisa Holsti, Marie-Noelle Wharton, Harold Siden, Tim F. Oberlander
Summary: Quality child health research requires multimodal, multi-informant, longitudinal tools for data collection to ensure a holistic description of real-world health, function, and well-being. However, the design of these tools has not typically included community input from families with children whose function spans the developmental spectrum.
JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
(2023)
Article
Microbiology
Emma Finlayson-Trick, Jacob Nearing, Jordie AJ. Fischer, Yvonne Ma, Siyun Wang, Hou Krouen, David M. Goldfarb, Crystal D. Karakochuk
Summary: This is the first published study on the effects of oral iron supplementation on the gut microbiomes of Cambodian women of reproductive age (WRA). It was found that iron supplementation with ferrous bisglycinate increased the abundance of Enterobacteriaceae, which includes Gram-negative enteric pathogens. The study also found an increase in the enteropathogenic Escherichia coli (EPEC) virulence gene, suggesting potential harm from iron supplementation.
MICROBIOLOGY SPECTRUM
(2023)
Article
Infectious Diseases
Sade Stenlund, Louise C. Masse, David Stenlund, Lauri Sillanmaki, Kirstin C. Appelt, Heli Koivumaa-Honkanen, Paivi Rautava, Sakari Suominen, David M. Patrick
Summary: This study analyzed the relationship between patients' psychosocial characteristics and antibiotic overuse. The results showed that adverse psychosocial characteristics were not directly related to increased antibiotic prescriptions, but were associated with poor general health status, which in turn was associated with more antibiotic prescriptions.
Article
Multidisciplinary Sciences
Martin A. Prusinkiewicz, Sadaf Sediqi, Ying Jie Li, David M. Goldfarb, Michael Asamoah-Boaheng, Nechelle Wall, Pascal M. Lavoie, Brian Grunau
Summary: This study investigated the impact of the interval between the first and second vaccine doses and between the second and third doses on the immunogenicity of the BNT162b2 vaccine. The results showed that longer intervals between doses were associated with increased immunogenicity. Increasing the interval between the second and third doses up to 8.9 months provided additional benefits in enhancing the immune response.
Article
Genetics & Heredity
A. Khan, A. M. Inkster, M. S. Penaherrera, S. King, S. Kildea, T. F. Oberlander, D. M. Olson, C. Vaillancourt, U. Brain, E. O. Beraldo, A. G. Beristain, V. L. Clifton, G. F. Del Gobbo, W. L. Lam, G. A. S. Metz, J. W. Y. Ng, E. M. Price, J. M. Schuetz, V. Yuan, E. Portales-Casamar, W. P. Robinson
Summary: This study analyzed DNAme data from 204 placentas from three cohorts to estimate epiphenotypes including gestational age, ancestry, and cell composition. The results showed that epigenetic gestational age was estimated accurately within 4 days of reported gestational age, and cell composition estimates varied within and between cohorts as well as over long placental processing times. The study also found that the ratio of cytotrophoblast to syncytiotrophoblast proportion decreased with increasing gestational age, and differed slightly by maternal ethnicity and genetic ancestry. The cohort of origin and cytotrophoblast proportion were the largest drivers of DNAme variation in the dataset.
EPIGENETICS & CHROMATIN
(2023)
Article
Pediatrics
Katelynn E. Boerner, Unma Desai, Jessica Luu, Karon E. Maclean, Tamara Munzner, Haley Foladare, Jane Shen, Javed Gill, Tim F. Oberlander
Summary: Data tracking is a common feature in pain e-health applications, but its potential as an intervention through data visualization has not been investigated. A feasibility trial was conducted with youth aged 12-18 years, using Ecological Momentary Assessment (EMA) data collection and a data visualization platform. Technical issues affected participant experience and data analysis, and only 48% of participants viewed the visualizations. Patient feedback is crucial for modifying the platform and addressing technical issues before a larger trial.
Article
Public, Environmental & Occupational Health
Marian Orhierhor, Clara Rubincam, Devon Greyson, Julie A. Bettinger
Summary: Canada's infant vaccination rate is below the national target, and vaccine hesitancy is a contributing factor in British Columbia's low coverage rates. This project examined mothers' concerns, information needs, and trusted sources regarding infant vaccines. The findings suggest that many mothers have unaddressed questions and concerns, indicating the need for continuous education for healthcare providers.
SSM-QUALITATIVE RESEARCH IN HEALTH
(2023)
Article
Health Care Sciences & Services
Devon Greyson, Wendy Pringle, Kumanan Wilson, Julie A. Bettinger
Summary: Given the controversy surrounding proof-of-vaccination credentials, this study aimed to explore the lessons learned from the experience with digital proof-of-vaccination credentials and provide recommendations for future use. The findings highlight the lack of consensus in various aspects of the technology and the importance of clear communication, evidence-based rationale, and multidisciplinary consultation.
