Effects of Lysine N-ζ-Methylation in Ultrashort Tetrabasic Lipopeptides (UTBLPs) on the Potentiation of Rifampicin, Novobiocin, and Niclosamide in Gram-Negative Bacteria

Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis

(2022) Yuxin Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clinical Status of Efflux Resistance Mechanisms in Gram-Negative Bacteria

(2021) Anne Davin-Regli et al.   Antibiotics-Basel

Dioctanoyl Ultrashort Tetrabasic β-Peptides Sensitize Multidrug-Resistant Gram-Negative Bacteria to Novobiocin and Rifampicin

(2021) Danyel Ramirez et al.   Frontiers in Microbiology

Bacterial Antibiotic Resistance: The Most Critical Pathogens

(2021) Giuseppe Mancuso et al.   Pathogens

Novel Stapling by Lysine Tethering Provides Stable and Low Hemolytic Cationic Antimicrobial Peptides

(2020) Hong Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dilipid Ultrashort Tetrabasic Peptidomimetics Potentiate Novobiocin and Rifampicin Against Multidrug-Resistant Gram-Negative Bacteria

(2020) Danyel Ramirez et al.   ACS Infectious Diseases

Potentiation of Antibiotics by a Novel Antimicrobial Peptide against Shiga Toxin Producing E. coli O157:H7

(2020) Juan Puño-Sarmiento et al.   Scientific Reports

Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin

(2020) Tianqi Liu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF)

(2020) Philip Storck et al.   Antibiotics-Basel

The Anthelmintic Drug Niclosamide Synergizes with Colistin and Reverses Colistin Resistance in Gram-Negative Bacilli

(2019) Ronald Domalaon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review

(2019) Mansura S. Mulani et al.   Frontiers in Microbiology

Outer membrane interaction kinetics of new polymyxin B analogs in Gram-negative bacilli

(2019) Noushin Akhoundsadegh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, An Intravenous Potentiator, After Single and Multiple Ascending Doses and When Combined with Beta-Lactam Antibiotics in Healthy Subjects

(2019) Paul B. Eckburg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics

(2019) Kristin R. Baker et al.   Frontiers in Cellular and Infection Microbiology

Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-Negative Bacteria

(2019) Temilolu Idowu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens?

(2018) Ronald Domalaon et al.   CLINICAL MICROBIOLOGY REVIEWS

A Tobramycin Vector Enhances Synergy and Efficacy of Efflux Pump Inhibitors against Multidrug-Resistant Gram-Negative Bacteria

(2017) Xuan Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Predictive compound accumulation rules yield a broad-spectrum antibiotic

(2017) Michelle F. Richter et al.   NATURE

A Gestalt approach to Gram-negative entry

(2016) Lynn L. Silver   BIOORGANIC & MEDICINAL CHEMISTRY

Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding

(2016) Aritreyee Datta et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Antimicrobial resistance: A global emerging threat to public health systems

(2015) Maurizio Ferri et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Trends and Exceptions of Physical Properties on Antibacterial Activity for Gram-Positive and Gram-Negative Pathogens

(2014) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Introduction to the CANWARD study (2007-11)

(2013) D. J. Hoban et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

LysineNε-Trimethylation, a Tool for Improving the Selectivity of Antimicrobial Peptides

(2010) María Fernández-Reyes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Defining Fractional Inhibitory Concentration Index Cutoffs for Additive Interactions Based on Self-Drug Additive Combinations, Monte Carlo Simulation Analysis, and In Vitro-In Vivo Correlation Data for Antifungal Drug Combinations against Aspergillus fumigatus

(2009) J. Meletiadis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial-Resistant Pathogens in Intensive Care Units in Canada: Results of the Canadian National Intensive Care Unit (CAN-ICU) Study, 2005-2006

(2008) G. G. Zhanel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY