Article
Fisheries
Cynthia Sequeiros, Marisa E. Garces, Melania Fernandez, Magali Marcos, Cecilia Castanos, Mariano Moris, Nelda L. Olivera
Summary: Autochthonous LAB strains isolated from Patagonian fish were able to colonize the intestine of zebrafish and modify the gut microbiota balance towards health-promoting bacteria.
AQUACULTURE INTERNATIONAL
(2022)
Article
Gastroenterology & Hepatology
Mengwei Jiang, Fengyuan Li, Yunhuan Liu, Zelin Gu, Lihua Zhang, Jiyeon Lee, Liqing He, Vatsalya Vatsalya, Huang-Ge Zhang, Zhongbin Deng, Xiang Zhang, Shao-Yu Chen, Grace L. Guo, Shirish Barve, Craig J. McClain, Wenke Feng
Summary: This study found that alcohol-induced dysbiosis increased the expression of intestinal miR194, which suppressed Fxr transcription. Lactobacillus rhamnosus GG-derived exosome-like nanoparticles (LDNPs) protected against ALD by regulating miR194-FXR signaling.
Article
Biotechnology & Applied Microbiology
Tibor Kereszteny, Balazs Libisch, Stephanya Corral Orbe, Tibor Nagy, Zoltan Kerenyi, Robert Kocsis, Katalin Posta, Peter P. Papp, Ferenc Olasz
Summary: This study evaluated the probiotic potential of 56 LAB isolates from wild boars, including their taxonomic identification, antibacterial activity, tolerance to pH and bile salt, antibiotic susceptibility, bile salt hydrolase activity, and lack of hemolysis. The genome sequences revealed the presence of genes and proteins associated with probiotic activity.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Chemistry, Multidisciplinary
Romain Villeger, Emilie Pinault, Karine Vuillier-Devillers, Karine Grenier, Cornelia Landolt, David Ropartz, Vincent Sol, Maria C. Urdaci, Philippe Bressollier, Tan-Sothea Ouk
Summary: This study found that using isomaltooligosaccharides (IMOSs) can improve the fitness and benefits of probiotic Bacillus subtilis CU1. IMOSs can modify the metabolism and functions of the strain, enhance the germination of Bacillus subtilis CU1, and increase the concentration of the strain.
APPLIED SCIENCES-BASEL
(2022)
Article
Biotechnology & Applied Microbiology
David Paz, Ricardo S. Aleman, Roberto Cedillos, Douglas W. Olson, Kayanush Aryana, Jhunior Marcia, Charles Boeneke
Summary: This study found that adding carao pulp powder in fermentation processes can improve the acid tolerance of S. thermophilus and enhance the bile tolerance and protease activity of both bacteria.
FERMENTATION-BASEL
(2022)
Article
Pharmacology & Pharmacy
Gopal Pawar, Eleni Papadatou-Soulou, Julie Mason, Rafeeq Muhammed, Alison Watson, Catherine Cotter, Mohamed Abdallah, Stuart Harrad, Claire Mackie, Tina Arien, Sabine Inghelbrecht, Hannah Batchelor
Summary: This study characterized gastric and intestinal fluid from paediatric populations, finding large inter-individual variability in pH, buffer capacity, osmolality, and bile acid concentration. Further research is needed to develop simulated paediatric media and explore their impact on drug solubility and dissolution.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2021)
Review
Immunology
Yada Duangnumsawang, Juergen Zentek, Farshad Goodarzi Boroojeni
Summary: Intestinal mucus is critical for protecting epithelial surfaces, supporting commensal bacteria, maintaining digestion, and facilitating nutrient transport. Goblet cell development and mucus production in poultry are influenced by age and dietary factors, affecting the mucosal barrier's protective mechanisms. Research on the impact of age and dietary factors on mucosal integrity in poultry needs further investigation.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Abeer I. M. EL-Sayed, Aliaa M. El-Borai, Sara H. Akl, Samy A. EL-Aassar, Mohamed S. Abdel-Latif
Summary: The main objective of this study was to isolate and determine the potential probiotic properties and enzyme production of several strains of lactic acid bacteria (LAB). The results showed that two LAB isolates exhibited antimicrobial activity against certain pathogenic strains and displayed favorable characteristics for survival and growth. Additionally, these isolates also demonstrated enzymatic activities, with one producing lipase and the other producing amylase and protease.
SCIENTIFIC REPORTS
(2022)
Article
Microbiology
Ayesha Lone, Walid Mottawea, Yasmina Ait Chait, Riadh Hammami
Summary: The poultry industry is rapidly growing, but safety concerns and the need for antibiotic alternatives are important. Salmonella and Clostridium perfringens are common pathogens, prompting the search for potential probiotics. Isolated strains showed inhibitory activity against major pathogens, with some exhibiting probiotic characteristics.
Article
Endocrinology & Metabolism
T. M. Zaved Waise, Yu-Mi Lim, Zahra Danaei, Song-Yang Zhang, Tony K. T. Lam
Summary: The TCDCA-FXR axis in the upper small intestine and ileum plays a crucial role in regulating local nutrient sensing and glucose homeostasis in rats. Transplantation of healthy microbiota and FXR inhibition can improve the nutrient sensing dysfunction caused by high-fat diet.
MOLECULAR METABOLISM
(2021)
Article
Food Science & Technology
Shaiful Adzni Sharifudin, Wan Yong Ho, Swee Keong Yeap, Rosmawati Abdullah, Soo Peng Koh
Summary: The study isolated and identified microorganisms from kombucha starters, finding high similarity towards acetic acid bacteria and yeast. These microorganisms showed different tolerance levels under low pH and bile salt environments, with the presence of acetic acid and ethanol in the kombucha samples indicating their potential as starter cultures for functional fermented beverages.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Jiaqian Yan, Yingjie Huang, Zining Gao, Zihao Zhang, Qing Gu, Ping Li
Summary: Lactic acid bacteria strain Lactiplantibacillus plantarum ZFM4 isolated from pickles showed probiotic properties, exhibiting suppression against pathogenic bacteria including Staphylococcus aureus and Pseudomonas aeruginosa, and tolerance to various stress conditions. Addition of ZFM4 in the fecal slurry fermentation model increased the abundance of Bacillota phylum and beneficial genera such as Lactiplantibacillus and Bifidobacterium. Furthermore, ZFM4 enhanced the production of several beneficial acids. Overall, ZFM4 has the potential to be a probiotic candidate.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biophysics
Ting Wang, Qiong Yin, Hao yang Huang, Zhenyu Wang, Haixing Song, Xiaoming Luo
Summary: The poor drug penetration in the hypoxia area of solid tumors poses a significant challenge for intestinal tumor therapy. In this study, the researchers developed a bacteria propelled micro-robot using Escherichia coli Nissle 1917 (EcN) bacteria to target and deliver drugs to the hypoxic region of intestinal tumors.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Multidisciplinary Sciences
Young Joo Oh, Seul-Ah Kim, Soo Hwi Yang, Da Hye Kim, Ya-Yun Cheng, Jung Il Kang, Sang Yun Lee, Nam Soo Han
Summary: This study analyzed the genome sequence of Lp. plantarum PMO 08 and confirmed its safety and probiotic characteristics at the genomic level. Several probiotic-related genes involved in acid/bile tolerance, adhesion ability, and oxidative stress response were detected through genome analysis.
Article
Microbiology
Zhili He, Tinghui Wang, Shichang Zhang, Kuojiang Shi, Fan Wang, Yanzhao Li, Chanqing Lin, Jianguo Chen
Summary: Bacteroides, a dominant bacterial genus in the human gut, has emerged as a potential next-generation probiotic with the ability to reduce cholesterol levels, prevent obesity, and lower the risk of cardiovascular disease. However, research on Bacteroides is currently limited, leaving room for exploration of the beneficial functions of different species in this genus.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Immunology
Carrie L. Shaffer, Ellisa W. Zhang, Anne G. Dudley, Beverly R. E. A. Dixon, Kirsten R. Guckes, Erin J. Breland, Kyle A. Floyd, Daniel P. Casella, Holly M. Scott Algood, Douglass B. Clayton, Maria Hadjifrangiskou
INFECTION AND IMMUNITY
(2017)
Article
Immunology
S. Beceiro, J. N. Radin, R. Chatuvedi, M. B. Piazuelo, D. J. Horvarth, H. Cortado, Y. Gu, B. Dixon, C. Gu, I. Lange, D-L T. Koomoa, K. T. Wilson, H. M. S. Algood, S. Partida-Sanchez
MUCOSAL IMMUNOLOGY
(2017)
Article
Multidisciplinary Sciences
Amber C. Beckett, John T. Loh, Abha Chopra, Shay Leary, Aung Soe Lin, Wyatt J. McDonnell, Beverly R. E. A. Dixon, Jennifer M. Noto, Dawn A. Israel, Richard M. Peek, Simon Mallal, Holly M. Scott Algood, Timothy L. Cover
Article
Immunology
Jessica A. Sutton, Lisa M. Rogers, Beverly R. E. A. Dixon, Leslie Kirk, Ryan Doster, Holly M. Algood, Jennifer A. Gaddy, Rebecca Flaherty, Shannon D. Manning, David M. Aronoff
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2019)
Article
Immunology
Sharia Yasmin, Beverly R. E. A. Dixon, Danyvid Olivares-Villagomez, Holly M. Scott Algood
INFECTION AND IMMUNITY
(2019)
Review
Immunology
Beverly R. E. A. Dixon, Rafat Hossain, Rachna V. Patel, Holly M. Scott Algood
INFECTION AND IMMUNITY
(2019)
Article
Microbiology
Aung Soe Lin, Mark S. McClain, Amber C. Beckett, Rhonda R. Caston, M. Lorena Harvey, Beverly R. E. A. Dixon, Anne M. Campbell, Jennifer H. B. Shuman, Neha Sawhney, Alberto G. Delgado, John T. Loh, M. Blanca Piazuelo, Holly M. Scott Algood, Timothy L. Cover
Article
Microbiology
Sarayu Bhogoju, Collins N. Khwatenge, Thyneice Taylor-Bowden, Gabriel Akerele, Boniface M. Kimathi, Joseph Donkor, Samuel N. Nahashon
Summary: The study suggests that Lactobacillus reuteri and Streptomyces coelicolor either separately or in combination have the potential to serve as probiotics in chickens, leading to improvements in body weight gain, feed consumption, and feed conversion ratios.
Article
Microbiology
Cara D. Varley, Lisa M. Rogers, Beverly REA. Dixon, Sarah C. Bernard, D. Borden Lacy, Emilio Sulpizio, David M. Aronoff, John M. Townes
Summary: This case report presents a rare occurrence of persistent bacteremia and psoas abscess caused by Paeniclostridium sordellii, without severe symptoms or toxic shock syndrome. Laboratory evaluation revealed that the isolated strain of Paeniclostridium sordellii lacked the lethal toxin gene and did not exhibit cytotoxicity to Vero cells.
Article
Microbiology
Aung Soe Lin, Jennifer H. B. Shuman, Ankita Kotnala, Jeff A. Shaw, Amber C. Beckett, Jennifer L. Harvey, Michael Tuck, Beverly R. E. A. Dixon, Michelle L. Reyzer, Holly M. Scott Algood, Kevin L. Schey, M. Blanca Piazuelo, Timothy L. Cover
Summary: Helicobacter pylori infection triggers alterations in gastric lipid composition, potentially serving as new biomarkers for gastric atrophy and premalignant changes prior to development of stomach cancer. These alterations have important functional consequences for H. pylori-host interactions and the pathogenesis of gastric cancer.
Article
Agronomy
Sarayu Bhogoju, Samuel Nahashon
Summary: Biotechnological advances are crucial for animal health, growth, and production performance. Probiotics have emerged as a safe alternative to antibiotics, minimizing the challenges faced by the livestock industry worldwide. They improve animal health, promote growth, and address consumer food safety concerns.
Article
Biochemistry & Molecular Biology
Sarayu Bhogoju, Shahid Khan, Anuradha Subramanian
Summary: This study demonstrates the ability of continuous low-intensity ultrasound (cLIUS) to preserve the chondrogenesis of MSCs in a proinflammatory environment. cLIUS acts by increasing the expression of SOX9 and COLII, stabilizing the NF kappa B complex in the cytoplasm, and restoring mitochondrial potential and mRNA expression, thus providing chondroprotective effects.
Meeting Abstract
Immunology
Holly Marie Scott Algood, Beverly R. E. A. Dixon, Tiffany J. Lee, M. Blanca Piazuelo
JOURNAL OF IMMUNOLOGY
(2021)