Article
Biochemistry & Molecular Biology
Ammara Saleem, Huma Khalid, Muhammad Furqan Akhtar, Alam Zeb
Summary: This study evaluated the antioxidant, anti-inflammatory, and anti-arthritic activities of Coronopus didymus. The extracts showed significant free radical scavenging activity and inhibited protein denaturation, as well as reducing inflammation and edema in arthritic rats. The extracts also had positive effects on blood parameters and oxidative stress biomarkers. These activities may be attributed to the presence of quercetin, ferulic acid, dihydromyricetin, apigenin, vitexin, and kaempferol in the extracts.
Review
Agriculture, Multidisciplinary
MDolores Maldonado, Jerusa Romero-Aibar, JRamon Calvo
Summary: This study reviewed the data regarding the benefits of melatonin in beer and suggested that moderate beer consumption, as part of a healthy diet or in certain physiological situations, can act as a protective factor and improve quality of life.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Review
Biochemistry & Molecular Biology
Alessio Nocentini, Alessandro Bonardi, Simone Pratesi, Paola Gratteri, Carlo Dani, Claudiu T. Supuran
Summary: Bilirubin is the final product of haem catabolism, and disruptions in its metabolic pathways can lead to increased plasma concentration, which may cause brain damage. However, bilirubin also has antioxidant and anti-inflammatory properties, making it a potential treatment for various diseases. This review discusses pharmaceutical strategies to reduce plasma bilirubin concentration and the therapeutic effects of bilirubin in different disorders.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Erick Poulsen-Silva, Felipe Gordillo-Fuenzalida, Patricia Velasquez, Felipe M. Llancalahuen, Rodrigo Carvajal, Mauricio Cabana-Brunod, Maria Carolina Otero
Summary: Honey is a highly appreciated mixture of compounds produced by bees, with multiple uses and potential nutritional and healing properties. This article focuses on the biological properties of different types of honey from Chile, specifically their antimicrobial, antioxidant, and anti-inflammatory activities. The review highlights the remarkable bioactive properties of Chilean honey, particularly its antimicrobial and antioxidant activities, with limited research on its anti-inflammatory effects. These properties are attributed to the presence of various bioactive components, such as phenolic compounds, hydrogen peroxide, enzymes, proteins, and carbohydrates. The biodiversity and environmental conditions of Chile contribute to the diverse bioactive compounds and biological properties found in Chilean honey. Further research is needed to explore the medicinal potential of these native honeys.
Review
Biotechnology & Applied Microbiology
Antonio Kleiton de Sousa, Anna Sofia Miranda Loiola Araujo, Tino Marcos Lino da Silva, Fernando Mesquita de Sousa de Lima, Jayro dos Santos Ferreira, Tarcisio Vieira de Brito, Andre Luiz dos Reis Barbosa
Summary: Sulfated polysaccharides (PLS) extracted from marine algae, particularly galactans, have shown significant anti-inflammatory effects in various inflammatory models. These molecules, characterized by the presence of sulfated groups in their chemical composition and rich in galactose, have demonstrated the ability to reduce oxidative stress parameters, cell migration, pro-inflammatory cytokines, tissue injury, and nociception. This systematic review aims to determine the effects of sulfated polysaccharides from seaweeds, especially galactans, in general and gastrointestinal tract inflammation.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Plant Sciences
Nadjat Righi, Sabah Boumerfeg, Amirouche Deghima, Pedro A. R. Fernandes, Elisabete Coelho, Faiza Baali, Susana M. Cardoso, Manuel A. Coimbra, Abderrahmane Baghiani
Summary: The hydromethanolic extract of Salvia verbenaca showed strong antioxidant and anti-inflammatory activities both in vitro and in vivo, with no acute/subacute toxicity effects on mice. This indicates its potential as a safe and effective option for wound healing and anti-ulcer treatments.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Nutrition & Dietetics
Gustavo Ignacio Vazquez-Cervantes, Daniela Ramirez Ortega, Tonali Blanco Ayala, Veronica Perez de la Cruz, Dinora Fabiola Gonzalez Esquivel, Aleli Salazar, Benjamin Pineda
Summary: Beer, a fermented beverage, contains rich nutritional components and has the potential to serve as a functional supplement with properties such as redox, anti-inflammatory, and anticarcinogenic effects. Hop derivatives in beer brewing provide potent antioxidants and immune response modulators.
Review
Biochemistry & Molecular Biology
Ioana Corina Bocsan, Dan Claudiu Magureanu, Raluca Maria Pop, Antonia Mihaela Levai, Stefan Octavian Macovei, Ioana Maria Patrasca, Veronica Sanda Chedea, Anca Dana Buzoianu
Summary: Grape pomace, a byproduct of the wine industry, is a reliable source of polyphenols with antioxidant and anti-inflammatory activities. Differences in antioxidant and anti-inflammatory activities exist between red and white grape pomace, with more focus on red grape pomace and the need for further research on white grape pomace.
Article
Oncology
Li Zhang, Jiang-Tao Zhang, Ya Huang, Guo-Kun Zhou, Yan Zhou, Jiang-Ping Yang, Tong Liu
Summary: The study demonstrates that melatonin has anti-itch effects on both acute and chronic itch in mice, possibly through melatonin receptors and its antioxidant and anti-inflammatory properties.
ANNALS OF TRANSLATIONAL MEDICINE
(2022)
Article
Plant Sciences
Tae-Hyu Kim, Van-Long Truong, Woo-Sik Jeong
Summary: The root extract of Ligularia fischeri Turcz has higher antioxidant capacity and total flavonoid levels, enhancing cellular antioxidant defense and exhibiting anti-inflammatory effects.
Article
Food Science & Technology
Qiuping Zou, Jian Feng, Ting Li, Guiguang Cheng, Weiguang Wang, Gaoxiong Rao, Hongping He, Yanping Li
Summary: In this study, the compounds in the extract of Nitraria Tangutorum Bobr. fruits were characterized, and their antioxidant activities and anti-inflammatory effects were evaluated. The extract exhibited strong antioxidant activity and protected against DSS-induced UC in mice by inhibiting the activation of the MAPK/NF-κB signaling pathway.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Nutrition & Dietetics
Kabelo Mokgalaboni, Wendy Nokhwezi Phoswa
Summary: This article investigates the efficacy of the plant-based remedy Corchorus olitorius in combating obesity and type 2 diabetes. The study found that C. olitorius significantly reduces blood glucose, body weight, total cholesterol, triglycerides, and low-density lipoprotein, while increasing high-density lipoprotein-cholesterol. It also reduces oxidative stress and inflammation, making it highly effective in improving symptoms of obesity and diabetes.
FRONTIERS IN NUTRITION
(2023)
Article
Chemistry, Multidisciplinary
Mi-Bo Kim, Hyeju Lee, Chaehyeon Lee, Yuqing Tan, Sang Gil Lee
Summary: The antioxidant activity of Ishige sinicola ethanol extract (ISE) and its fractions, particularly the butanol (BuOH) fraction, can protect against lipopolysaccharide (LPS)-induced muscle atrophy by attenuating the diameter of muscle cells and inhibiting muscle-specific E3 ubiquitin ligase expression. This protection may be mediated through the inhibition of pro-inflammatory cytokine and inflammation-inducible enzyme expression via the p38/extracellular signal-regulated kinase signaling pathway.
APPLIED SCIENCES-BASEL
(2023)
Article
Acoustics
Elizabeth Macias-Cortes, Jose Alberto Gallegos-Infante, Nuria Elizabeth Rocha-Guzman, Martha Rocio Moreno-Jimenez, Veronica Cervantes-Cardoza, Gustavo Adolfo Castillo-Herrera, Ruben Francisco Gonzalez-Laredo
Summary: Salvilla is widely used in treatments against gastrointestinal disorders due to its antioxidant and anti-inflammatory potential. In this study, ultrasound-assisted extraction and ethanolic solutions were used to extract salvilla. The extracts contained a high amount of flavonoids and exhibited good antioxidant and anti-inflammatory activities. Treatment T6 (75% ethanol, 30% amplitude and 10 min extraction time) showed the highest flavonoid content, antioxidant activity, and anti-inflammatory potential.
ULTRASONICS SONOCHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Alejandra Vanessa Lopez-Corona, Illeen Valencia-Espinosa, Fabio Antonio Gonzalez-Sanchez, Angelica Lizeth Sanchez-Lopez, Luis Eduardo Garcia-Amezquita, Rebeca Garcia-Varela
Summary: Raspberries contain a wide range of phenolic compounds that have antioxidant and anti-inflammatory activities, which may be beneficial for the treatment of chronic degenerative diseases and cancer.
Article
Endocrinology & Metabolism
Helen F. Galley, Barry McCormick, Kirsten L. Wilson, Damon A. Lowes, Lesley Colvin, Carole Torsney
JOURNAL OF PINEAL RESEARCH
(2017)
Letter
Biochemistry & Molecular Biology
Beverley E. Minter, Damon A. Lowes, Nigel R. Webster, Helen F. Galley
Article
Clinical Neurology
Rachel Vaughan, Helen F. Galley, Saravana Kanakarajan
Summary: This study aimed to describe the extent of sleep problems in patients with chronic non-malignant pain using different validated sleep assessment tools, finding that chronic pain has a significant impact on sleep regardless of the assessment tool used, and suggesting that the sleep interference question in the BPI could be used to identify sleep problems in patients with chronic pain.
BRITISH JOURNAL OF PAIN
(2022)
Review
Substance Abuse
Maria A. Bantounou
Summary: The Covid-19 pandemic has led to increased alcohol consumption due to stress and isolation. This has resulted in higher risks of contracting SARS-CoV-2 and worsened Covid-19 infection severity. Healthcare professionals should provide support to vulnerable groups and promote stress reduction, healthy habits, and limited alcohol consumption.
JOURNAL OF ADDICTIVE DISEASES
(2023)
Letter
Infectious Diseases
Ronan M. Docherty, Helen F. Galley
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Urology & Nephrology
Maria A. Bantounou, Josip Plascevic, Lewis MacDonald, Man Chun Wong, Neasa O'Connell, Helen F. Galley
Summary: Pembrolizumab and enfortumab vedotin are novel treatment options for patients with locally advanced or metastatic UC, offering superior outcomes and tolerability compared to standard chemotherapy.
Article
Education, Scientific Disciplines
Maria Anna Bantounou, Niraj Kumar
Summary: To enhance doctors' engagement with research, the National Medical Research Association (NMRA) developed a research teaching series, delivering peer-led (PL) sessions by medical students and conventional teacher-led (CL) sessions by licensed physicians/lecturers. We assessed the effectiveness of the series and compared the PL and CL approaches.
MEDICAL SCIENCE EDUCATOR
(2023)
Review
Endocrinology & Metabolism
Maria Anna Bantounou, Panagiotis Sardellis, Rosa Thuemmler, Daniel Black Boada, Justyna Kaczmarek, Ribeya Mahmood, Josip Plascevic, Sam Philip
Summary: This study investigated the renal safety profile of sotagliflozin, a new inhibitor of sodium-glucose co-transporter-1 and -2, in patients with type 1 and type 2 diabetes. The results showed that sotagliflozin did not adversely affect renal function and did not change the risk of key renal outcomes, even in patients with pre-existing renal impairment.
DIABETES OBESITY & METABOLISM
(2023)
Article
Behavioral Sciences
Damon A. Lowes, Helen F. Galley, Alessandro P. S. Moura, Nigel R. Webster
BEHAVIOURAL BRAIN RESEARCH
(2017)
