Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology

HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations

(2021) Raheem Fazal et al.   EMBO JOURNAL

An autopsy case of pure nigropathy with TUBA4A nonsense mutation

(2021) Keitaro Okada et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

(2021) Laura Fumagalli et al.   Science Advances

Novel TUBA4A Variant Associated With Familial Frontotemporal Dementia

(2021) Merel O. Mol et al.   Neurology-Genetics

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

(2021) Seiichi Nagano et al.   Frontiers in Molecular Neuroscience

The tubulin code and its role in controlling microtubule properties and functions

(2020) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases

(2020) Antonella Sferra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Axonal transport defects and neurodegeneration: Molecular mechanisms and therapeutic implications

(2019) Wenting Guo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Influence of selenium on the emergence of neuro tubule defects in a neuron-like cell line and its implications for amyotrophic lateral sclerosis

(2019) Tullia Maraldi et al.   NEUROTOXICOLOGY

Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS

(2018) Anika M. Helferich et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clinical and biological phenotypes of frontotemporal dementia: Perspectives for disease modifying therapies

(2017) S. Gazzina et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tubulins and brain development – The origins of functional specification

(2017) Martin W. Breuss et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients

(2017) Federica Perrone et al.   NEUROBIOLOGY OF AGING

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

(2017) Wenting Guo et al.   Nature Communications

Molecular Determinants of Tubulin’s C-Terminal Tail Conformational Ensemble

(2016) Kathryn P. Wall et al.   ACS Chemical Biology

The emerging role of the tubulin code: From the tubulin molecule to neuronal function and disease

(2016) Soumyananda Chakraborti et al.   Cytoskeleton

A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease

(2016) Jayden A. Clark et al.   Frontiers in Cellular Neuroscience

TUBA4A gene analysis in sporadic amyotrophic lateral sclerosis: identification of novel mutations

(2015) Viviana Pensato et al.   JOURNAL OF NEUROLOGY

Frontotemporal dementia

(2015) Jee Bang et al.   LANCET

Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS

(2014) Bradley N. Smith et al.   NEURON

A harmonized classification system for FTLD-TDP pathology

(2011) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

(2011) Katya Rascovsky et al.   BRAIN

Classification of primary progressive aphasia and its variants

(2011) M. L. Gorno-Tempini et al.   NEUROLOGY

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

(2010) Hazel Urwin et al.   ACTA NEUROPATHOLOGICA