Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein
出版年份 2022 全文链接
标题
Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein
作者
关键词
-
出版物
Frontiers in Cell and Developmental Biology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-03-02
DOI
10.3389/fcell.2022.830432
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human Microcephaly Protein RTTN Is Required for Proper Mitotic Progression and Correct Spindle Position
- (2021) En-Ju Chou et al. Cells
- Cell stress in cortical organoids impairs molecular subtype specification
- (2020) Aparna Bhaduri et al. NATURE
- Loss of CPAP in developing mouse brain and its functional implication in human primary microcephaly
- (2020) Yi-Nan Lin et al. JOURNAL OF CELL SCIENCE
- Human Brain Organoids to Decode Mechanisms of Microcephaly
- (2020) Elke Gabriel et al. Frontiers in Cellular Neuroscience
- Centrosome defects cause microcephaly by activating the 53BP1‐USP28‐TP53 mitotic surveillance pathway
- (2020) Thao P Phan et al. EMBO JOURNAL
- Mechanism and Regulation of Centriole and Cilium Biogenesis
- (2019) David K. Breslow et al. Annual Review of Biochemistry
- Heterogeneous clinical phenotypes and cerebral malformations reflected by rotatin cellular dynamics
- (2019) Laura V Vandervore et al. BRAIN
- Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
- (2019) Wei Zhang et al. Nature Communications
- CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis
- (2019) Jhih-Jie Tsai et al. Scientific Reports
- The Genetics of Primary Microcephaly
- (2018) Divya Jayaraman et al. Annual Review of Genomics and Human Genetics
- Once and only once: mechanisms of centriole duplication and their deregulation in disease
- (2018) Erich A. Nigg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects
- (2018) Jessica Neville Little et al. HUMAN MOLECULAR GENETICS
- Genes and molecular pathways underpinning ciliopathies
- (2017) Jeremy F. Reiter et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
- (2017) Hsin-Yi Chen et al. Nature Communications
- Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease
- (2017) Rui Li et al. Protein & Cell
- CPAP promotes timely cilium disassembly to maintain neural progenitor pool
- (2016) Elke Gabriel et al. EMBO JOURNAL
- CEP295 interacts with microtubules and is required for centriole elongation
- (2016) Ching-Wen Chang et al. JOURNAL OF CELL SCIENCE
- Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length
- (2016) Xiangdong Zheng et al. Nature Communications
- CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination
- (2015) Marko Marjanović et al. Nature Communications
- Cortical neurogenesis in the absence of centrioles
- (2014) Ryan Insolera et al. NATURE NEUROSCIENCE
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis
- (2014) X. Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CEP120 and SPICE1 Cooperate with CPAP in Centriole Elongation
- (2013) David Comartin et al. CURRENT BIOLOGY
- Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly
- (2013) Yu-Chih Lin et al. EMBO JOURNAL
- CEP120 interacts with CPAP and positively regulates centriole elongation
- (2013) Yi-Nan Lin et al. JOURNAL OF CELL BIOLOGY
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- STIL is required for centriole duplication in human cells
- (2012) J. Vulprecht et al. JOURNAL OF CELL SCIENCE
- Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome
- (2012) Rebecca E. McIntyre et al. PLoS Genetics
- The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
- (2011) Chieh-Ju C Tang et al. EMBO JOURNAL
- Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL
- (2011) D. Kitagawa et al. JOURNAL OF CELL SCIENCE
- A new subtype of progenitor cell in the mouse embryonic neocortex
- (2011) Xiaoqun Wang et al. NATURE NEUROSCIENCE
- Mitotic catastrophe: a mechanism for avoiding genomic instability
- (2011) Ilio Vitale et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DrosophilaAna2 is a conserved centriole duplication factor
- (2010) Naomi R. Stevens et al. JOURNAL OF CELL BIOLOGY
- Neurogenic radial glia in the outer subventricular zone of human neocortex
- (2010) David V. Hansen et al. NATURE
- OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling
- (2010) Simone A Fietz et al. NATURE NEUROSCIENCE
- Control of Centriole Length by CPAP and CP110
- (2009) Thorsten I. Schmidt et al. CURRENT BIOLOGY
- Overly Long Centrioles and Defective Cell Division upon Excess of the SAS-4-Related Protein CPAP
- (2009) Gregor Kohlmaier et al. CURRENT BIOLOGY
- CPAP is a cell-cycle regulated protein that controls centriole length
- (2009) Chieh-Ju C. Tang et al. NATURE CELL BIOLOGY
- Primary microcephaly: do all roads lead to Rome?
- (2009) Gemma K. Thornton et al. TRENDS IN GENETICS
- Mechanisms of Asymmetric Stem Cell Division
- (2008) Juergen A. Knoblich CELL
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
- (2008) G Kroemer et al. CELL DEATH AND DIFFERENTIATION
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