Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies

Coenzyme Q redox signalling and longevity

(2021) Filippo Scialo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dramatic changes in mitochondrial substrate use at critically high temperatures: a comparative study using Drosophila

(2021) Lisa Bjerregaard Jørgensen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

(2021) Xiaoyu Xu et al.   Cell Death & Disease

Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster

(2020) Filippo Scialo et al.   Redox Biology

Serine Catabolism Feeds NADH when Respiration Is Impaired

(2020) Lifeng Yang et al.   Cell Metabolism

Integration of GC-MS and LC-MS For Untargeted Metabolomics Profiling

(2020) Özge Cansın Zeki et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Mitochondrial ubiquinol oxidation is necessary for tumour growth

(2020) Inmaculada Martínez-Reyes et al.   NATURE

A potassium channel β-subunit couples mitochondrial electron transport to sleep

(2019) Anissa Kempf et al.   NATURE

Acute O 2 Sensing: Role of Coenzyme QH 2 /Q Ratio and Mitochondrial ROS Compartmentalization

(2018) Ignacio Arias-Mayenco et al.   Cell Metabolism

Control of mitochondrial superoxide production by reverse electron transport at complex I

(2018) Ellen L. Robb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila

(2018) Zaijun Ma et al.   eLife

Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy

(2018) Sukru Anil Dogan et al.   Cell Metabolism

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

(2018) Jeroen Baardman et al.   Cell Reports

The role of mitochondrial ROS in the aging brain

(2017) Rhoda Stefanatos et al.   FEBS LETTERS

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

(2017) Oliver D. K. Maddocks et al.   NATURE

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

(2016) Filippo Scialò et al.   Cell Metabolism

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

Choline and dimethylglycine produce superoxide/hydrogen peroxide from the electron transport chain in liver mitochondria

(2016) Ryan J. Mailloux et al.   FEBS LETTERS

Practical Recommendations for the Use of the GeneSwitch Gal4 System to Knock-Down Genes in Drosophila melanogaster

(2016) Filippo Scialo et al.   PLoS One

Mito-priming as a method to engineer Bcl-2 addiction

(2016) Jonathan Lopez et al.   Nature Communications

The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency

(2016) Adela Guarás et al.   Cell Reports

Mitochondrial ROS production correlates with, but does not directly regulate lifespan in drosophila

(2016) Alberto Sanz et al.   Aging-US

Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling

(2015) M. Carmen Fernández-Agüera et al.   Cell Metabolism

Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells

(2015) Andreas Kuehne et al.   MOLECULAR CELL

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

(2014) Chendong Yang et al.   MOLECULAR CELL

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Sources of superoxide/H2O2 during mitochondrial proline oxidation

(2014) Renata L.S. Goncalves et al.   Redox Biology

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling

(2013) Edward Owusu-Ansah et al.   CELL

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

(2011) Helena M. Cochemé et al.   Cell Metabolism

In Vivo Mapping of Hydrogen Peroxide and Oxidized Glutathione Reveals Chemical and Regional Specificity of Redox Homeostasis

(2011) Simone C. Albrecht et al.   Cell Metabolism

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

(2011) Kathryn V. Tormos et al.   Cell Metabolism

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Biomarkers of aging in Drosophila

(2010) Jake Jacobson et al.   AGING CELL

Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster

(2010) Jian-Ching Ren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster

(2010) Alberto Sanz et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Pyrroline-5-carboxylate synthase and proline biosynthesis: From osmotolerance to rare metabolic disease

(2010) Isabel Pérez-Arellano et al.   PROTEIN SCIENCE

Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response

(2009) Markus Ralser et al.   NATURE BIOTECHNOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL