A Unique Spectrum of Spontaneous Tumors in Dino Knockout Mice Identifies Tissue-Specific Requirements for Tumor Suppression

p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino

(2021) Christina B. Marney et al.   Cell Reports

From genotype to phenotype: genetics of mammalian long non-coding RNAs in vivo

(2021) Daniel Andergassen et al.   NATURE REVIEWS GENETICS

A mechanistic view of long noncoding RNAs in cancer

(2021) Lauren Winkler et al.   Wiley Interdisciplinary Reviews-RNA

The Oncogenic and Tumor Suppressive Functions of the Long Noncoding RNA MALAT1: An Emerging Controversy

(2020) Qingjuan Chen et al.   Frontiers in Genetics

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

(2020) James P. Hewitson et al.   JOURNAL OF IMMUNOLOGY

Expanded encyclopaedias of DNA elements in the human and mouse genomes

(2020) Jill E. Moore et al.   NATURE

LncRNAMalat1inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity

(2020) Wei Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-coding RNAs, guardians of the p53 galaxy

(2020) Song Chen et al.   SEMINARS IN CANCER BIOLOGY

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression

(2019) Qinqiang Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy

(2019) Jennifer Ocasio et al.   Nature Communications

Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors

(2018) Peixin Dong et al.   Frontiers in Genetics

Neat1 is a p53-inducible lincRNA essential for transformation suppression

(2017) Stephano S. Mello et al.   GENES & DEVELOPMENT

Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology

(2017) Adam M. Schmitt et al.   Cold Spring Harbor Perspectives in Medicine

Expanding the p53 regulatory network: LncRNAs take up the challenge

(2016) Elena Grossi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

An inducible long noncoding RNA amplifies DNA damage signaling

(2016) Adam M Schmitt et al.   NATURE GENETICS

Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma

(2015) Chang-Lung Lee et al.   Nature Communications

p53 and Medulloblastoma

(2015) Vijay Ramaswamy et al.   Cold Spring Harbor Perspectives in Medicine

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas

(2015) Lorena Landuzzi et al.   Oncotarget

Strain Background Determines Lymphoma Incidence in Atm Knockout Mice

(2015) Paula C. Genik et al.   NEOPLASIA

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

(2013) Liz J. Valente et al.   Cell Reports

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

(2012) Tongyuan Li et al.   CELL

Loss of the abundant nuclear non-coding RNAMALAT1is compatible with life and development

(2012) Moritz Eißmann et al.   RNA Biology

The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult

(2012) Bin Zhang et al.   Cell Reports

Mutual exclusivity analysis identifies oncogenic network modules

(2011) G. Ciriello et al.   GENOME RESEARCH

Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice

(2011) Shinichi Nakagawa et al.   JOURNAL OF CELL BIOLOGY

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages

(2011) D. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 Research: The Past Thirty Years and the Next Thirty Years

(2010) D. Lane et al.   Cold Spring Harbor Perspectives in Biology

PUMA Suppresses Intestinal Tumorigenesis in Mice

(2009) W. Qiu et al.   CANCER RESEARCH

Timed Somatic Deletion of p53 in Mice Reveals Age-Associated Differences in Tumor Progression

(2009) George Hinkal et al.   PLoS One

Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma

(2008) Ulrich Schüller et al.   CANCER CELL

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL