Characterization of Temozolomide Resistance Using a Novel Acquired Resistance Model in Glioblastoma Cell Lines

Targeting Cell Cycle Checkpoint Kinases to Overcome Intrinsic Radioresistance in Brain Tumor Cells

(2022) Tijana Vlatkovic et al.   Cancers

Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in TP53 or PTEN Tumor Suppressors

(2021) Aleksandra Ellert-Miklaszewska et al.   Cancers

Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma

(2020) Marion Rabé et al.   Cell Death & Disease

LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma

(2020) Boyang Liu et al.   Cell Death & Disease

Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma

(2020) Alessandra Ferri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

(2020) Barbara Oldrini et al.   Nature Communications

Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities

(2019) Paul Daniel et al.   Frontiers in Oncology

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

(2019) Graham MacLeod et al.   Cell Reports

Temozolomide-associated hypermutation in gliomas

(2018) Serah Choi et al.   NEURO-ONCOLOGY

Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma

(2018) D. M. Tiek et al.   Scientific Reports

Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma

(2018) Ann-Christin Nickel et al.   JOURNAL OF NEURO-ONCOLOGY

Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma

(2017) et al.   Cancers

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance

(2016) Laura Garros-Regulez et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A comprehensive profile of recurrent glioblastoma

(2016) B Campos et al.   ONCOGENE

Cancer stem cells in glioblastoma

(2015) Justin D. Lathia et al.   GENES & DEVELOPMENT

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

(2015) Hoon Kim et al.   GENOME RESEARCH

A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells

(2015) Anna-Maria Barciszewska et al.   PLoS One

Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression

(2015) Gloria Perazzoli et al.   PLoS One

Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy

(2014) B Auffinger et al.   CELL DEATH AND DIFFERENTIATION

The epidemiology of glioma in adults: a "state of the science" review

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme

(2013) N. El Hindy et al.   NEURO-ONCOLOGY

Targeting cancer stem cells to suppress acquired chemotherapy resistance

(2013) S J Vidal et al.   ONCOGENE

Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

(2013) Anna V. Knizhnik et al.   PLoS One

Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells

(2012) Chung Heon Ryu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells

(2012) Aditi Nadkarni et al.   JOURNAL OF NEURO-ONCOLOGY

Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase

(2012) Ketki Karanam et al.   MOLECULAR CELL

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas

(2011) Jörg Felsberg et al.   INTERNATIONAL JOURNAL OF CANCER

MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase-Mediated HOX/Stem Cell Gene Signature

(2010) N. Gaspar et al.   CANCER RESEARCH

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain

(2010) Claudia R. Oliva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MSH6 Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance

(2009) S. Yip et al.   CLINICAL CANCER RESEARCH

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences

(2009) Marie Brázdová et al.   NUCLEIC ACIDS RESEARCH

EdU, a new thymidine analogue for labelling proliferating cells in the nervous system

(2008) Fatemah Chehrehasa et al.   JOURNAL OF NEUROSCIENCE METHODS