Article
Obstetrics & Gynecology
Chengjun Liu, Ketong Su, Lu Chen, Zijiao Zhao, Xin Wang, Chenfeng Yuan, Yuqi Liang, Huili Ji, Chunjin Li, Xu Zhou
Summary: The research identified 129 differentially expressed genes associated with high developmental competence of oocytes, and confirmed that COL1A2 and renin can be used to evaluate oocyte quality and embryo developmental competence through RNA sequencing and qRT-PCR.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Review
Biochemistry & Molecular Biology
Mara Simopoulou, Anna Rapani, Sokratis Grigoriadis, Agni Pantou, Petroula Tsioulou, Evangelos Maziotis, Despina Tzanakaki, Olga Triantafyllidou, Theodoros Kalampokas, Charalampos Siristatidis, Panagiotis Bakas, Nikolaos Vlahos
Summary: The article discusses the infertility associated with endometriosis, highlighting the various pathological mechanisms that contribute to impaired reproductive dynamics. Reactive oxygen species, immune system dysregulation, and cellular architectural disruption are key mechanisms affecting oocyte and embryo development potential in endometriosis patients.
Article
Oncology
Yongdong Dai, Xiang Lin, Na Liu, Libing Shi, Feng Zhuo, Qianmeng Huang, Weijia Gu, Fanxuan Zhao, Yi Zhang, Yinli Zhang, Yinbin Pan, Songying Zhang
Summary: Endometriosis is a common gynecological disorder that causes female infertility. Excessive oxidative stress in ovaries of endometriosis patients induced senescence of cumulus granulosa cells. Our research analyzed the transcriptomic and metabolomic profiles of follicles in a mouse model of endometriosis and in patients with endometriosis, and investigated the potential function of changed metabolites in granulosa cells.
JOURNAL OF PATHOLOGY
(2023)
Article
Obstetrics & Gynecology
Jiayi Guo, Haitao Zeng, Tingting Li, Xiaoyan Liang, Jintao Peng
Summary: This study explored the expression profiles of mRNAs, lncRNAs, and circRNAs in granulosa cells of infertile women with ovarian endometriosis, constructing networks and analyzing the roles of differentially expressed mRNAs through GO and KEGG pathways. The findings provide insights into the underlying etiology of endometriosis-related infertility, with differentially upregulated mRNAs enriched in pathways such as MAPK signaling and FoxO signaling.
REPRODUCTIVE SCIENCES
(2022)
Article
Fisheries
Yaorong Wang, Zhiyuan Li, Yuwen Guo, Chuntai Nong, Charles Brighton Ndandala, Hao Yang, Hai Huang, Guangli Li, Huapu Chen
Summary: In this study, lncRNAs and mRNAs involved in IGF3-induced ovarian maturation were evaluated in spotted scat (Scatophagus argus). The results demonstrate that lncRNAs might be involved in the reproductive processes in S. argus.
AQUACULTURE REPORTS
(2022)
Review
Endocrinology & Metabolism
Weisen Fan, Zheng Yuan, Muzhen Li, Yingjie Zhang, Fengjuan Nan
Summary: Infertility and menstrual abnormalities in endometriosis patients are often caused by aberrant follicular growth or reduced ovarian reserve. Endometriosis does not directly harm the oocyte but inhibits the function of granulosa cells, resulting in decreased oocyte quality. Aberrant states such as granulosa cell apoptosis, inflammation, oxidative stress, steroid synthesis obstacle, and aberrant mitochondrial energy metabolism in endometriosis can affect oocyte development and quality.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Guangyin Xi, Lei An, Wenjing Wang, Jing Hao, Qianying Yang, Lizhu Ma, Jinlun Lu, Yue Wang, Wenjuan Wang, Wei Zhao, Juan Liu, Mingyao Yang, Xiaodong Wang, Zhenni Zhang, Chao Zhang, Meiqiang Chu, Yuan Yue, Fusheng Yao, Meijia Zhang, Jianhui Tian
Summary: CNP-NPR2-cGMP signaling cascade is essential for oocyte meiosis, while TTP plays a critical role in LH-induced Nppc mRNA degradation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Endocrinology & Metabolism
Yanmei Li, Naihui Wang, Yuanxue Jing, Jiajing He, Fangfang Li, Xuehong Zhang
Summary: This study found that FTO concentrations in follicular fluid of women with ovarian endometriosis are significantly decreased, while the level of m(6)A is increased.
GYNECOLOGICAL ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yang-Ching Chen, Yen-Chia Yeh, Yu-Fang Lin, Heng-Kien Au, Shih-Min Hsia, Yue-Hwa Chen, Rong-Hong Hsieh
Summary: Frequent consumption of diet drinks, specifically those with aspartame, is associated with negative effects on fertility, including oocyte dysmorphism and decreased embryo quality. Aspartame consumption leads to disrupted estrus cycle, reduced anti-Mullerian hormone level, increased oxidative stress in the ovaries, and decline in mitochondrial function, which affects follicle preservation and steroidogenesis in granulosa cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Obstetrics & Gynecology
Aranzazu Bosch, Sonia Albero, Juan Carlos Castillo, Jorge Ten, Jaime Guerrero, Jose Antonio-Ortiz, Andrea Bernabeu, Rafael Bernabeu
Summary: This study retrospectively evaluated the ovarian response, fertilization rate, embryo development, and clinical outcomes of 115 young oocyte donors who received the SARS-CoV-2 vaccine. The results showed that post-vaccination stimulation required longer duration and higher dosage of gonadotrophins, but the quality of retrieved oocytes and transferred embryos were not affected. Therefore, mRNA SARS-CoV-2 vaccination does not have adverse effects on ovarian response in young oocyte donors.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Reproductive Biology
Atefeh Abedini, David A. Landry, Angus D. Macaulay, Het Vaishnev, Ashna Parbhakar, Dalia Ibrahim, Reza Salehi, Vincent Maranda, Elizabeth Macdonald, Barbara C. Vanderhyden
Summary: The study investigates the role of BRG1 in female fertility using mutant mice. Depletion of Brg1 in granulosa cells causes sterility, while depletion in oocytes results in subfertility. These findings highlight the importance of BRG1 in regulating granulosa and oocyte functions during follicle growth and its necessity for oocyte developmental competence.
BIOLOGY OF REPRODUCTION
(2023)
Article
Biochemistry & Molecular Biology
Nian Li, Yinqi Zhou, Jiali Cai, Yifei Wang, Xiaofeng Zhou, Mengting Hu, Yubin Li, Hao Zhang, Jiaqi Li, Bing Cai, Xiaolong Yuan
Summary: Previous studies have shown that long noncoding RNAs (lncRNAs) play an attractive role in the remodeling of mammalian tissues. In this study, it was found that the migration of granulosa cells (GCs) in ovarian follicles promoted follicular remodeling. The actin gamma 1 (ACTG1) was shown to significantly promote the migration and proliferation while inhibiting the apoptosis of GCs, suggesting its requirement for ovarian remodeling. Additionally, a trans-regulatory lncRNA of ACTG1 (TRLA) was identified, which was targeted by histone H3 lysine 4 acetylation (H3K4ac) and facilitated GCs migration, proliferation, and inhibited apoptosis through the miR-26a/HMGA1 axis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Medicine, General & Internal
Judith-Marie Mifsud, Livia Pellegrini, Mauro Cozzolino
Summary: Ovarian endometriosis affects fertility, but oocyte cryopreservation offers the opportunity to preserve fertility and achieve a live birth for patients diagnosed with this condition.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Saba Nikanfar, Hajar Oghbaei, Yeganeh Rastgar Rezaei, Reza Zarezadeh, Davoud Jafari-gharabaghlou, Hamid Reza Nejabati, Zahra Bahrami, Nathalie Bleisinger, Naser Samadi, Amir Fattahi, Mohammad Nouri, Ralf Dittrich
Summary: Adipokines play a crucial role in female fertility research by influencing ovarian functions, being essential for normal ovarian function, and being associated with ovary-related disorders.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Svetlana Uzbekova, Ana-Paula Teixeira-Gomes, Aurelie Marestaing, Peggy Jarrier-Gaillard, Pascal Papillier, Ekaterina N. Shedova, Galina N. Singina, Rustem Uzbekov, Valerie Labas
Summary: In this study, 84 palmitoylated proteins were identified in bovine ovarian follicle cells, among which variations in abundance of these proteins during oocyte maturation were observed. The involvement of palmitoyl-proteins in oxidation-reduction processes, energy metabolism, protein localization, vesicle transport, stress response, and signaling pathways suggests that protein palmitoylation may play important roles in oocyte maturation and follicle communications mediated by ffEVs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
C. L. Wu, T. Zhao, S. Zhang, Z. Y. Wang, C. H. Zhang, J. Z. Tan
Summary: Surface machining techniques such as cutting, rolling, and grinding were used to machine 304 austenitic stainless steels in order to enhance the hardening layer and corrosion resistance. Among the tested samples, the rolling sample exhibited the best surface quality with the lowest surface roughness and fewest defects. The rolling sample also displayed the highest degree of work hardening and corrosion resistance, attributed to the residual compressive stress and fewer micro-defects.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2023)
Article
Materials Science, Multidisciplinary
Guangyan Wang, Sugui Tian, Ning Tian, Xinjie Zhu, Shunke Zhang, Song Zhang
Summary: This study investigated the stacking fault energy and creep mechanism of a single-crystal nickel-based superalloy at different temperatures. The results revealed that the stacking fault energy increased with temperature and that the presence of element Ru significantly reduced the stacking fault energy compared to other elements in the alloy. The creep mechanism involved <110> super-dislocation shearing into the gamma ' phase below 850 degrees C, which could be decomposed into (a/3) <112> partial dislocations and super-lattice intrinsic stacking fault. However, above 850 degrees C, the resistance to dislocation decomposition increased, and the a <110> super-dislocation did not decompose when it cut into the gamma ' phase along the {111} plane.
MATERIALS SCIENCE AND TECHNOLOGY
(2023)
Article
Fisheries
Felix Gyawu Addo, Songhe Zhang, Benjamin Manirakiza, Yu Ma, Shudong Yuan, Salah Alden Alklaf, Shaozhuang Guo, Godwin Abakari
Summary: In this study, a 30-day culture trial was conducted to investigate the effects of brown sugar addition on nutrient removal, feed conversion ratio, growth performance, and microbial community in a rice straw-based biofloc shrimp system. The results showed that the addition of brown sugar significantly reduced ammonium and nitrite nitrogen concentrations and improved nutrient removal rates. Furthermore, the addition of brown sugar also resulted in lower feed conversion ratio and higher shrimp survival rates. The dominant microbial phyla identified in all treatments played a crucial role in nutrient cycling and promoting water quality.
Article
Environmental Sciences
Xin He, Songhe Zhang, Xin Lv, Min Liu, Yu Ma, Shaozhuang Guo
Summary: This study investigated the role of rhizospheric biofilms on methane release in wastewater stabilization ponds (WSPs) with floating plants. The results showed that E. crassipes effectively reduced methane release and nutrients, with a higher inhibition effect on CH4 fluxes in treatments with high nutrients. Additionally, the rhizospheric bacterial community contributed to nutrients removal. In conclusion, E. crassipes plants play an important role in reducing methane release and nutrients removal.
Article
Environmental Sciences
Liu Yang, Songhe Zhang, Xin Lv, Yuansi Liu, Shaozhuang Guo, Xiuren Hu, Benjamin Manirakiza
Summary: This study investigated the impacts of Vallis-neria natans senescence on methanotroph community and methane release in wetlands. The results showed that nutrient loadings increased methane fluxes, while healthy V. natans plants reduced methane flux. Environmental parameters and the physiological status of V. natans affected methanotrophs.
ENVIRONMENTAL RESEARCH
(2023)
Review
Materials Science, Multidisciplinary
Ying Sun, Wenchao Hu, Chenliang Wu, Hai Kuang, Jie Wang, Song Zhang, Tingting Yan, Qiang Wang
Summary: This paper reviews the research progress of 3D printing titanium alloys, focusing on the basic phases, alloying elements and mechanical properties of titanium alloys, and discusses the effects of defects, microstructures and surface roughness on fatigue properties. It also introduces the research progress of mechanical properties of porous titanium alloys, including the influence of structural design, microstructure and surface roughness on fatigue properties. Finally, future development trends and potential research topics are pointed out.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2023)
Article
Oncology
Yongdong Dai, Xiang Lin, Na Liu, Libing Shi, Feng Zhuo, Qianmeng Huang, Weijia Gu, Fanxuan Zhao, Yi Zhang, Yinli Zhang, Yinbin Pan, Songying Zhang
Summary: Endometriosis is a common gynecological disorder that causes female infertility. Excessive oxidative stress in ovaries of endometriosis patients induced senescence of cumulus granulosa cells. Our research analyzed the transcriptomic and metabolomic profiles of follicles in a mouse model of endometriosis and in patients with endometriosis, and investigated the potential function of changed metabolites in granulosa cells.
JOURNAL OF PATHOLOGY
(2023)
Article
Chemistry, Physical
Chao Wang, Maomao Gong, Yongjun Cheng, Victor Kimberg, Xiao-Jing Liu, Oriol Vendrell, Kiyoshi Ueda, Song Bin Zhang
Summary: We suggest using a femtosecond X-ray pulse to trigger Resonant Auger scattering (RAS) in a distorted molecule, which provides information on the core-valence electronic transition and impresses a rich fingerprint of the electronic structure and nuclear configuration. By controlling the amount of molecular distortion with varied time delay, the RAS measurements imprint both their electronic structures and changing geometries. This work showcases a new alternative pump-probe technique for mapping the core and valence dynamics with ultrashort X-ray probe pulses.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Materials Science, Coatings & Films
Qizhong Li, Tao Huang, Mai Yang, Tenghua Gao, Baifeng Ji, Song Zhang, Lianmeng Zhang, Rong Tu
Summary: Hard coatings with gradient and multilayer structures were prepared by high-power pulsed magnetron sputtering. The modulation period was found to significantly affect the microstructure, mechanical, and tribological properties of the coatings. Shorter modulation periods improved the adhesion strength and resulted in higher hardness and lower friction coefficients.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Genetics & Heredity
Jiamin Jin, Peipei Ren, Xiang Li, Yinyi Zhang, Weijie Yang, Yerong Ma, Mengru Lai, Chao Yu, Songying Zhang, Yin-Li Zhang
Summary: Histone deacetylation is observed in granulosa cells during the process of ovulation, which is mediated by FSH and hCG. This process is regulated by CK2 alpha-mediated HDAC2 phosphorylation and is essential for successful ovulation.
EPIGENETICS & CHROMATIN
(2023)
Article
Obstetrics & Gynecology
Yichao Tian, Jin Huang, Chi-Chiu Wang, Huizhen Lin, Xiaona Huang, Yue Zhao, Liu Liu, Songying Zhang
Summary: The value of endometrial scratch in women with recurrent embryo transfer is controversial, and it is unclear if endometrial scratch in the previous mid-luteal phase affects the whole genome transcriptomic profile of peri-implantation endometrium in the subsequent cycle.
Article
Chemistry, Physical
Song Zhang, Wei Liu, Weimin Wang, Ying Gao, Aiyang Wang, Qianglong He, Wenhui Bai, Runfeng Li
Summary: This article uses a thermal-electric-mechanical coupled model to simulate the spark plasma sintering process of boron carbide, and conducts parameter optimization and simulation analysis.
Article
Materials Science, Ceramics
Kai Liu, Lei Qiu, Yuzhen Zhang, Yanying Du, Ce Sun, Song Zhang, Rong Tu, Yanjiao Wu, Huajun Sun, Yusheng Shi
Summary: A material extrusion (MEX) technology was developed for additive manufacturing of continuous carbon fiber-reinforced silicon carbide ceramic (C-f/SiC) composites. A slurry with high solid loading and viscosity was proposed based on rheological properties. Complex structures of C-f/SiC composites were printed using this MEX technique. Phenolic resin impregnation-carbonization process and reactive melting infiltration (RMI) were used to prepare samples with different C-f contents, with the highest bending strength and fracture toughness achieved at 1 K C-f content.
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
(2023)
Article
Obstetrics & Gynecology
Xiaomei Tong, Jiamin Jin, Yamei Xue, Lu Fang, Haiyan Zhu, Lingying Jiang, Songying Zhang
Summary: This study investigated the clinical outcomes of frozen-thawed blastocyst transfers derived from zygotes with no or one pronucleus (0PN or 1PN). The results showed that the developmental potential and clinical outcomes of 0PN and 1PN embryos were similar to those of 2PN embryos in both IVF and ICSI cycles. This suggests that 0PN and 1PN embryos from ICSI cycles can be transferred when there is an insufficient number of 2PN embryos.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Cell & Tissue Engineering
Ying-Yi Zhang, Weijie Yang, Yi Zhang, Zhanhong Hu, Yingyan Chen, Yerong Ma, Anran Yang, Zhan Shi, Hanjing Zhou, Peipei Ren, Libing Shi, Jiamin Jin, Yan Rong, Xiaomei Tong, Yin-Li Zhang, Songying Zhang
Summary: Follicle developmental capacity and oocyte quality decline with advanced maternal age. Extracellular vesicles from human umbilical cord mesenchymal stem cells (HucMSC-EVs) have potential therapeutic effects on age-related ovarian dysfunction. In vitro culture (IVC) of preantral follicles is a useful method for understanding follicle development and improving female fertility. This study demonstrated that HucMSC-EVs can improve the growth and quality of aged follicles and oocytes in vitro through gene transcription regulation.
STEM CELL REVIEWS AND REPORTS
(2023)