Bad to the Bone: The Effects of Therapeutic Glucocorticoids on Osteoblasts and Osteocytes
出版年份 2022 全文链接
标题
Bad to the Bone: The Effects of Therapeutic Glucocorticoids on Osteoblasts and Osteocytes
作者
关键词
-
出版物
Frontiers in Endocrinology
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-03-31
DOI
10.3389/fendo.2022.835720
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Leukemia inhibitory factor treatment attenuates the detrimental effects of glucocorticoids on bone in mice
- (2021) Sooyeon Lee et al. BONE
- Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
- (2021) Xiaonan Liu et al. Nature Communications
- The cytokine interleukin-11 crucially links bone formation, remodeling and resorption
- (2021) Birte Kespohl et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Glucocorticoid-induced autophagy and apoptosis in bone
- (2020) Tiantian Wang et al. APOPTOSIS
- Targeting autophagy in osteoporosis: From pathophysiology to potential therapy
- (2020) Xu Li et al. AGEING RESEARCH REVIEWS
- Denosumab vs risedronate in glucocorticoid-induced osteoporosis: final results of a 24-month randomized, double-blind, double-dummy trial
- (2019) Kenneth G. Saag et al. Arthritis & Rheumatology
- Osteogenic Dkk1 Mediates Glucocorticoid-Induced but Not Arthritis-Induced Bone Loss
- (2019) Juliane Colditz et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Regulation of sclerostin in glucocorticoid-induced osteoporosis (GIO) in mice and humans
- (2019) Sylvia Thiele et al. Endocrine Connections
- Trabecular bone score improves fracture risk assessment in glucocorticoid-induced osteoporosis
- (2019) Helena Florez et al. RHEUMATOLOGY
- LncRNA EPIC1 protects human osteoblasts from dexamethasone-induced cell death
- (2018) Xiang-yang Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
- (2018) Ping Yang et al. BONE
- Autophagy: a promising target for age-related osteoporosis
- (2018) Tiantian Wang et al. CURRENT DRUG TARGETS
- Glucocorticoids and bone: consequences of endogenous and exogenous excess and replacement therapy
- (2018) Rowan S Hardy et al. ENDOCRINE REVIEWS
- Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells
- (2018) Wanlin Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Low-dose dexamethasone affects osteoblast viability by inducing autophagy via intracellular ROS
- (2018) Shaokun Zhang et al. Molecular Medicine Reports
- Therapeutic Mechanisms of Glucocorticoids
- (2018) Jolien Vandewalle et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
- (2018) Susanne Hildebrandt et al. Scientific Reports
- Denosumab versus risedronate in glucocorticoid-induced osteoporosis: a multicentre, randomised, double-blind, active-controlled, double-dummy, non-inferiority study
- (2018) Kenneth G Saag et al. Lancet Diabetes & Endocrinology
- DVO Leitlinie 2017 zur Prophylaxe, Diagnostik und Therapie der Osteoporose bei postmenopausalen Frauen und Männern
- (2018) F. Thomasius et al. Osteologie
- Osteoblast autophagy in glucocorticoid-induced osteoporosis
- (2018) Lufei Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dexamethasone induces osteoblast apoptosis through ROS-PI3K/AKT/GSK3β signaling pathway
- (2018) Shuang Deng et al. BIOMEDICINE & PHARMACOTHERAPY
- Autophagy relieves the function inhibition and apoptosis‑promoting effects on osteoblast induced by glucocorticoid
- (2017) Yudi Han et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Animal models to explore the effects of glucocorticoids on skeletal growth and structure
- (2017) Claire L Wood et al. JOURNAL OF ENDOCRINOLOGY
- Effect of β‑ecdysterone on glucocorticoid‑induced apoptosis and autophagy in osteoblasts
- (2017) Yang‑Hua Tang et al. Molecular Medicine Reports
- Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
- (2017) Kenneth G. Saag et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis
- (2017) Tristan W. Fowler et al. Scientific Reports
- 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis
- (2017) Lenore Buckley et al. Arthritis & Rheumatology
- Cortical bone loss caused by glucocorticoid excess requires RANKL production by osteocytes and is associated with reduced OPG expression in mice
- (2016) Marilina Piemontese et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing activity
- (2016) H. Herschel Conaway et al. BONE
- A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis
- (2016) Geetha Mohan et al. CALCIFIED TISSUE INTERNATIONAL
- Glucocorticoid Signaling and Bone Biology
- (2016) T. Komori HORMONE AND METABOLIC RESEARCH
- Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis
- (2016) Paul D. Miller et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin
- (2016) Amy Y Sato et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Osteocytic signalling pathways as therapeutic targets for bone fragility
- (2016) Lilian I. Plotkin et al. Nature Reviews Endocrinology
- Romosozumab Treatment in Postmenopausal Women with Osteoporosis
- (2016) Felicia Cosman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy
- (2016) Kerstin Hartmann et al. PHYSIOLOGICAL REVIEWS
- Continuous corticosterone delivery via the drinking water or pellet implantation: A comparative study in mice
- (2016) Sylvia J. Gasparini et al. STEROIDS
- Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes
- (2016) Junjie Gao et al. Oncotarget
- Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation
- (2016) Peng Liu et al. Scientific Reports
- Mesenchymal progenitors in osteopenias of diverse pathologies: differential characteristics in the common shift from osteoblastogenesis to adipogenesis
- (2016) Bingdong Sui et al. Scientific Reports
- Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss
- (2015) Neng-Yu Lin et al. ANNALS OF THE RHEUMATIC DISEASES
- Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone
- (2015) Marilina Piemontese et al. BONE
- Glucocorticoids: Dose-related effects on osteoclast formation and function via reactive oxygen species and autophagy
- (2015) Jun Shi et al. BONE
- Prevention of glucocorticoid induced bone changes with beta-ecdysone
- (2015) Weiwei Dai et al. BONE
- Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice
- (2015) Amy Y. Sato et al. BONE
- Sclerostin antibody and interval treadmill training effects in a rodent model of glucocorticoid-induced osteopenia
- (2015) Zahra Achiou et al. BONE
- Fracture risk in oral glucocorticoid users: a Bayesian meta-regression leveraging control arms of osteoporosis clinical trials
- (2015) M. A. Amiche et al. OSTEOPOROSIS INTERNATIONAL
- Sclerostin-antibody treatment of glucocorticoid-induced osteoporosis maintained bone mass and strength
- (2015) W. Yao et al. OSTEOPOROSIS INTERNATIONAL
- P53 Dependent Mitochondrial Permeability Transition Pore Opening Is Required for Dexamethasone-Induced Death of Osteoblasts
- (2014) Yun-fang Zhen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Glucocorticoids and bone: local effects and systemic implications
- (2014) Holger Henneicke et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Endogenous Glucocorticoids and Bone
- (2014) Hong Zhou et al. Bone Research
- MicroRNA-29a Protects Against Glucocorticoid-Induced Bone Loss and Fragility in Rats by Orchestrating Bone Acquisition and Resorption
- (2013) Feng-Sheng Wang et al. ARTHRITIS AND RHEUMATISM
- Effect of glucocorticoid treatment on Wnt signalling antagonists (sclerostin and Dkk-1) and their relationship with bone turnover
- (2013) L. Gifre et al. BONE
- MicroRNA-29a ameliorates glucocorticoid-induced suppression of osteoblast differentiation by regulating β-catenin acetylation
- (2013) Jih-Yang Ko et al. BONE
- Glucocorticoids and osteocyte autophagy
- (2013) Wei Yao et al. BONE
- Comparative effects of teriparatide and risedronate in glucocorticoid-induced osteoporosis in men: 18-month results of the EuroGIOPs trial
- (2013) Claus-C Glüer et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Glucocorticoids Antagonize RUNX2 During Osteoblast Differentiation in Cultures of ST2 Pluripotent Mesenchymal Cells
- (2013) Theodora Koromila et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation
- (2013) J Li et al. Cell Death & Disease
- Acute Effects of Glucocorticoids on Serum Markers of Osteoclasts, Osteoblasts, and Osteocytes
- (2012) Kristyna Brabnikova Maresova et al. CALCIFIED TISSUE INTERNATIONAL
- Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases
- (2012) Hua Zhu Ke et al. ENDOCRINE REVIEWS
- Selective glucocorticoid receptor modulation maintains bone mineral density in mice
- (2012) Sylvia Thiele et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Glucocorticoid Receptor and Sequential P53 Activation by Dexamethasone Mediates Apoptosis and Cell Cycle Arrest of Osteoblastic MC3T3-E1 Cells
- (2012) Hui Li et al. PLoS One
- Advanced imaging assessment of bone fragility in glucocorticoid-induced osteoporosis
- (2011) Banu B. Kalpakcioglu et al. BONE
- Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)
- (2011) Adolfo Díez-Pérez et al. BONE
- Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism
- (2011) Holger Henneicke et al. BONE
- MKP-1 Knockout Does not Prevent Glucocorticoid-Induced Bone Disease in Mice
- (2011) Maria M. Conradie et al. CALCIFIED TISSUE INTERNATIONAL
- Regulation of osteoblast differentiation by interleukin-11 via AP-1 and Smad signaling [Review]
- (2011) Toshio Matsumoto et al. ENDOCRINE JOURNAL
- Osteoprotegerin Prevents Glucocorticoid-Induced Osteocyte Apoptosis in Mice
- (2011) Robert S. Weinstein et al. ENDOCRINOLOGY
- An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation
- (2011) Alexander Rauch et al. FASEB JOURNAL
- Glucocorticoid dose determines osteocyte cell fate
- (2011) Junjing Jia et al. FASEB JOURNAL
- Glucocorticoids and Tumor Necrosis Factor α Increase Oxidative Stress and Suppress Wnt Protein Signaling in Osteoblasts
- (2011) Maria Almeida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Matrix-embedded cells control osteoclast formation
- (2011) Jinhu Xiong et al. NATURE MEDICINE
- Evidence for osteocyte regulation of bone homeostasis through RANKL expression
- (2011) Tomoki Nakashima et al. NATURE MEDICINE
- Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation
- (2010) Joseph S Butler et al. BMC MUSCULOSKELETAL DISORDERS
- Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor
- (2010) Alexander Rauch et al. Cell Metabolism
- Intermittent Parathyroid Hormone Administration Counteracts the Adverse Effects of Glucocorticoids on Osteoblast and Osteocyte Viability, Bone Formation, and Strength in Mice
- (2010) Robert S. Weinstein et al. ENDOCRINOLOGY
- Dissociation of Osteogenic and Immunological Effects by the Selective Glucocorticoid Receptor Agonist, Compound A, in Human Bone Marrow Stromal Cells
- (2010) Martina Rauner et al. ENDOCRINOLOGY
- Perspectives bone histomorphometry in glucocorticoid-induced osteoporosis
- (2010) David W. Dempster JOURNAL OF BONE AND MINERAL RESEARCH
- Role of the negative glucocorticoid regulatory element in glucocorticoid repression of the human osteocalcin promoter
- (2010) Nigel Morrison et al. JOURNAL OF BONE AND MINERAL RESEARCH
- High-dose glucocorticoids in multiple sclerosis patients exert direct effects on the kidney and skeleton
- (2010) F. Cosman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Altered trabecular architecture induced by Corticosteroids: A Bone Histomorphometric Study
- (2010) D. Chappard et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Glucocorticoid-induced autophagy in osteocytes
- (2010) Xuechun Xia et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin a transcription in primary osteoblast cultures
- (2010) Yankel Gabet et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
- (2009) Robert S. Weinstein et al. AGING CELL
- Prevention of glucocorticoid-induced bone loss in mice by inhibition of RANKL
- (2009) Lorenz C. Hofbauer et al. ARTHRITIS AND RHEUMATISM
- Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial
- (2009) Kenneth G. Saag et al. ARTHRITIS AND RHEUMATISM
- Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice
- (2009) Robert Kalak et al. BONE
- Biphasic Glucocorticoid-Dependent Regulation of Wnt Expression and Its Inhibitors in Mature Osteoblastic Cells
- (2009) Wendy Mak et al. CALCIFIED TISSUE INTERNATIONAL
- MAP Kinase Phosphatase-1 Protects against Inflammatory Bone Loss
- (2009) R. Sartori et al. JOURNAL OF DENTAL RESEARCH
- Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial
- (2009) David M Reid et al. LANCET
- Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts
- (2009) Je-Ken Chang et al. TOXICOLOGY
- Adverse events of low- to medium-dose oral glucocorticoids in inflammatory diseases: a meta-analysis
- (2008) J N Hoes et al. ANNALS OF THE RHEUMATIC DISEASES
- Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: A longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice
- (2008) Wei Yao et al. ARTHRITIS AND RHEUMATISM
- BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: Potential therapeutic targets for glucocorticoid-induced osteoporosis
- (2008) Kumi Hayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Modulation of Dickkopf-1 Attenuates Glucocorticoid Induction of Osteoblast Apoptosis, Adipocytic Differentiation, and Bone Mass Loss
- (2008) Feng-Sheng Wang et al. ENDOCRINOLOGY
- BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization
- (2008) Cynthia A. Luppen et al. GROWTH FACTORS
- Regulation of bim in glucocorticoid-mediated osteoblast apoptosis
- (2007) B. Espina et al. JOURNAL OF CELLULAR PHYSIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation