Accumulation of acetaldehyde in aldh2.1 zebrafish causes increased retinal angiogenesis and impaired glucose metabolism

Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations

(2021) Haozhe Qi et al.   Advanced Science

Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments

(2020) Konstantinos A. Toulis et al.   DRUGS

Rare causes of hypoglycemia in adults

(2020) Claire Douillard et al.   ANNALES D ENDOCRINOLOGIE

Activation of NADPH/ROS pathway contributes to angiogenesis through JNK signaling in brain endothelial cells

(2020) Zairan Wang et al.   MICROVASCULAR RESEARCH

Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans

(2020) Bowen Lou et al.   Redox Biology

Acrolein: A Potential Mediator of Oxidative Damage in Diabetic Retinopathy

(2020) Moaddey Alfarhan et al.   Biomolecules

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium

(2019) Nicolas Ricard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Frizzled 4 regulates ventral blood vessel remodeling in the zebrafish retina

(2019) Lucia Caceres et al.   DEVELOPMENTAL DYNAMICS

Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications and other age-related diseases

(2019) Casper Schalkwijk et al.   PHYSIOLOGICAL REVIEWS

Isoform-Specific Roles of ERK1 and ERK2 in Arteriogenesis

(2019) Nicolas Ricard et al.   Cells

Glyoxalase 1 Modulation in Obesity and Diabetes

(2018) Naila Rabbani et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of alcohol on plasma glucose and prevention of alcohol-induced hypoglycemia in type 1 diabetes-A systematic review with GRADE

(2018) R. Tetzschner et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes

(2018) Dagmar Schumacher et al.   Molecular Metabolism

Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease

(2018) Nordin M.J. Hanssen et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Novel subgroups of patients with adult-onset diabetes in Chinese and US populations

(2018) Xiantong Zou et al.   Lancet Diabetes & Endocrinology

The pathology associated with diabetic retinopathy

(2017) Judith Lechner et al.   VISION RESEARCH

Plastic roles of pericytes in the blood–retinal barrier

(2017) Do Young Park et al.   Nature Communications

Evidence-based tailoring of bioinformatics approaches to optimize methods that predict the effects of nonsynonymous amino acid substitutions in glucokinase

(2017) Daniela Šimčíková et al.   Scientific Reports

Zebrafish ( Danio rerio ) embryo as a platform for the identification of novel angiogenesis inhibitors of retinal vascular diseases

(2016) Sara Rezzola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

4-HNE expression in diabetic rat kidneys and the protective effects of probucol

(2016) G. Liu et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Clinical Relevance of Biomarkers of Oxidative Stress

(2015) Jeroen Frijhoff et al.   ANTIOXIDANTS & REDOX SIGNALING

High glucose-induced changes in hyaloid-retinal vessels during early ocular development of zebrafish: a short-term animal model of diabetic retinopathy

(2015) Seung-Hyun Jung et al.   BRITISH JOURNAL OF PHARMACOLOGY

Assay of methylglyoxal and glyoxal and control of peroxidase interference

(2014) Paul J. Thornalley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Poly peak parser: Method and software for identification of unknown indels using sanger sequencing of polymerase chain reaction products

(2014) Jonathon T. Hill et al.   DEVELOPMENTAL DYNAMICS

Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples

(2014) Naila Rabbani et al.   Nature Protocols

Plasma IgA antibody levels to malondialdehyde acetaldehyde-adducts are associated with inflammatory mediators, obesity and type 2 diabetes

(2013) Lauri Vehkala et al.   ANNALS OF MEDICINE

Pericytes in the eye

(2013) Frederick Pfister et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p38α MAPK regulates myocardial regeneration in zebrafish

(2012) Chris Jopling et al.   CELL CYCLE

Aldehyde dehydrogenases: From eye crystallins to metabolic disease and cancer stem cells

(2012) Vasilis Vasiliou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Aldehyde dehydrogenases in cellular responses to oxidative/electrophilicstress

(2012) Surendra Singh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy

(2011) Ling Jing et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

ALDH2 in alcoholic heart diseases: Molecular mechanism and clinical implications

(2011) Yingmei Zhang et al.   PHARMACOLOGY & THERAPEUTICS

Mitochondrial aldehyde dehydrogenase and cardiac diseases

(2010) Che-Hong Chen et al.   CARDIOVASCULAR RESEARCH

Significantly increased levels of serum malonaldehyde in type 2 diabetics with myocardial infarction

(2010) M Mohsin et al.   International Journal of Diabetes in Developing Countries

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia

(2009) Kara K. Osbak et al.   HUMAN MUTATION

Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice

(2009) Grant R. Budas et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal

(2008) Henry Jay Forman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Polymorphism of ethanol-metabolism genes and alcoholism: Correlation of allelic variations with the pharmacokinetic and pharmacodynamic consequences

(2008) Yi-Chyan Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

(2008) Satori A Marchitti et al.   Expert Opinion on Drug Metabolism & Toxicology