Review
Nutrition & Dietetics
Mengjun Wang, Junliang Liu, Zhao Zhang, Haixiong Zhang, Ning Wang, Xi Chen, Xuemei Han, Qian Lu, Shanshan Chi
Summary: Dietary intervention may help decrease IL-6 levels in patients with MetS, but it does not significantly affect IL-1 beta, TNF-alpha, or CRP levels.
FRONTIERS IN NUTRITION
(2022)
Review
Food Science & Technology
Zhonghui Jiang, Hua Qu, Keji Chen, Zhuye Gao
Summary: The study synthesized evidence from ten RCTs and found that FA supplementation could reduce inflammatory markers, such as hs-CRP, IL-6, and TNF-α in MetS patients, but had no significant impact on CRP levels.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Endocrinology & Metabolism
Linjie Qiu, Chunyang Gao, Haonan Wang, Yan Ren, Jixin Li, Meijie Li, Xinlei Du, Wenjie Li, Jin Zhang
Summary: This systematic review and meta-analysis examined the effectiveness and safety of dietary polyphenol curcumin supplement on metabolic, inflammatory, and oxidative stress indices in patients with metabolic syndrome. The results showed that curcumin had positive effects on waist circumference, fasting blood sugar, diastolic blood pressure, high-density lipoprotein cholesterol, tumor necrosis factor-a, C-reactive protein, and malondialdehyde. However, further studies are needed to confirm these findings.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Maria Magdalena Quetglas-Llabres, Margalida Monserrat-Mesquida, Cristina Bouzas, Cristina Gomez, David Mateos, Tomas Ripoll-Vera, Josep A. Tur, Antoni Sureda
Summary: Studies have found that MetS patients with low adherence to MDP have higher levels of glycated haemoglobin A1c and triglycerides, as well as lower levels of HDL cholesterol. Those with low adherence to MDP also have higher plasma levels of pro-inflammatory markers, lower antioxidant enzyme activity, and more severe cellular oxidative stress responses. Patients with higher adherence to MDP showed less altered anthropometric parameters, blood biochemical profile, and better oxidative and inflammatory status.
Article
Nutrition & Dietetics
Martin Ming Him Wong, Kwan Yi Chan, Kenneth Lo
Summary: This review examines the association between dietary and environmental manganese exposure and the risk of metabolic syndrome (MetS). The findings suggest that the levels of manganese from diet, serum, urine, and whole blood do not have a significant association with MetS. However, some studies indicate a non-linear relationship between urinary and blood manganese levels and MetS, and higher dietary manganese may be associated with a lower MetS risk in certain studies.
Review
Environmental Sciences
Hugo Lamat, Marie-Pierre Sauvant-Rochat, Igor Tauveron, Reza Bagheri, Ukadike C. Ugbolue, Salwan Maqdasi, Valentin Navel, Frederic Dutheil
Summary: The study found that there is a relationship between pesticide exposure and metabolic syndrome. Exposure to pesticides and their contaminants increases the risk of metabolic syndrome, especially for organochlorines. The use of pesticides worldwide may be increasing over time. There is also an inverse relationship between body mass index and male gender.
ENVIRONMENTAL POLLUTION
(2022)
Article
Cardiac & Cardiovascular Systems
Gladys P. Velarde, Naila Choudhary, Katia Bravo-Jaimes, Carmen Smotherman, Saadia Sherazi, Dale F. Kraemer
Summary: The study found that high-intensity atorvastatin had a significant impact on lipogenesis and apolipoproteins in women with metabolic syndrome, but did not lower levels of inflammatory, thrombotic and platelet activity markers. Further research is needed to explore the use of statins for primary prevention in these patients.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Review
Pharmacology & Pharmacy
Yu Ye, Xiufen Liu, Ninghua Wu, Yanqi Han, Jiawen Wang, Yuandong Yu, Qingjie Chen
Summary: This study conducted a systematic review and meta-analysis of berberine treatment on metabolic disorders, finding that berberine can effectively improve obesity and metabolic disorders, making it a promising option for clinical treatment.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Ya-Fei Liu, Huan-Huan Wang, Yin-Hong Geng, Liang Han, Sheng-Hao Tu, Hui Wang
Summary: The prevalence of metabolic syndrome (MetS) is increasing worldwide, leading to MetS-associated kidney disease. Traditional theories suggest using multiple medications to control blood pressure, lipid levels, blood glucose, and obesity, as well as improve insulin resistance. However, this approach may reduce patients' compliance and increase adverse reactions. Therefore, complementary and alternative medicine, such as berberine (BBR), is being explored for its potential efficacy and safety in addressing MetS through various pathways and targets. This article elaborates on the effects and mechanisms of BBR on different aspects of MetS and kidney diseases, highlighting the need for further clinical trials.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pediatrics
Natasha A. Schvey, Lisa M. Shank, Marian Tanofsky-Kraff, Sophie Ramirez, Deborah R. Altman, Taylor Swanson, Alex G. Rubin, Nichole R. Kelly, Sarah LeMay-Russell, Meghan E. Byrne, Megan N. Parker, Miranda M. Broadney, Sheila M. Brady, Susan Z. Yanovski, Jack A. Yanovski
Summary: Research did not find any association between weight-based teasing and worsened cardiometabolic health among youth in two different samples. Longitudinal studies are needed to further explore the relationship between weight stigma and health outcomes in young people.
Review
Environmental Sciences
Ping Xu, Aiping Liu, Fengna Li, Alexey A. Tinkov, Longjian Liu, Ji-Chang Zhou
Summary: Research has found a positive association between heavy metal exposure and MetS, with participants exposed to heavy metals having a higher likelihood of developing MetS. Further studies are needed to explore the effects of individual metals and their interactions on the relationship between MetS and heavy metals.
ENVIRONMENTAL POLLUTION
(2021)
Review
Immunology
Nami Mohammadian Khonsari, Fereshteh Baygi, Ozra Tabatabaei-Malazy, Sahar Mohammadpoor Nami, Amir Ehsani, Sasan Asadi, Mostafa Qorbani
Summary: Individuals with normal weight can suffer from obesity based on body fat percentage, known as normal weight obesity (NWO), and have an increased risk of significant morbidity and mortality compared to the general population. Inflammatory pathways and chronic inflammation seem to be significant contributors to the pathogenicity of NWO. This study found that high levels of CRP and IL6 were associated with NWO.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Endocrinology & Metabolism
Tingting Che, Cheng Yan, Dingyuan Tian, Xin Zhang, Xuejun Liu, Zhongming Wu
Summary: The study found that both short and long sleep significantly increased the risk of metabolic syndrome, with a U-shaped relationship between sleep duration and metabolic syndrome risk. Both short and long sleep increased the risk of obesity and high blood pressure, while short sleep may also increase the risk of high blood sugar.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Health Care Sciences & Services
Nayoung Ahn, Kijin Kim
Summary: Combined endurance and dynamic-resistance exercise can improve physical fitness and MS risk factors in elderly women, relieving vascular inflammation and improving antioxidant function.
Article
Plant Sciences
Guanyu Wang, Dong Shang, Guixin Zhang, Shenglin Zhang, Nan Jiang, Huanhuan Liu, Hailong Chen
Summary: This study used a systematic review and meta-analysis to investigate the effect of QingYi decoction on inflammatory markers in acute pancreatitis patients. The results suggest that QingYi decoction can reduce pro-inflammatory markers while increasing anti-inflammatory markers.
Article
Health Care Sciences & Services
Feng Chang, Yue Xi, Jie Zhao, Xiaojian Zhang, Yun Lu
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2017)
Article
Multidisciplinary Sciences
Yun Lu, Xiuze Jin, Cheng-a-xin Duan, Feng Chang
Article
Medicine, General & Internal
Yuqiong Lu, Zhanjing Dai, Yun Lu, Feng Chang
Summary: Biological disease-modifying anti-rheumatic drugs (bDMARDs) appear to significantly improve the quality of life (QoL) in patients with psoriatic arthritis (PsA). Further studies are needed to confirm the effects of bDMARDs as compared to other therapeutic agents.
