Review
Food Science & Technology
Pablo Hernandez-Alonso, Hatim Boughanem, Silvia Canudas, Nerea Becerra-Tomas, Maria Fernandez de la Puente, Nancy Babio, Manuel Macias-Gonzalez, Jordi Salas-Salvado
Summary: This systematic review and meta-analysis revealed an inverse association between circulating vitamin D levels and colorectal cancer risk.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Oncology
Yazhou He, Xiaomeng Zhang, Maria Timofeeva, Susan M. Farrington, Xue Li, Wei Xu, Harry Campbell, Richard S. Houlston, Ian P. Tomlinson, Evropi Theodoratou, Malcolm G. Dunlop
Summary: A bidirectional Mendelian randomization study found no significant causal effect of vitamin D on colorectal cancer risk, nor any reverse causal association between genetically increased CRC risk and vitamin D levels; this suggests that associations reported in observational studies may be primarily driven by unidentified confounders.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Public, Environmental & Occupational Health
Su H. Chu, Mengna Huang, Rachel S. Kelly, Priyadarshini Kachroo, Augusto A. Litonjua, Scott T. Weiss, Jessica Lasky-Su
Summary: This study found that higher levels of maternal vitamin D in the third trimester are associated with a lower risk of ADHD in offspring, with a stronger effect observed in male offspring.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Nutrition & Dietetics
Linnea Huss, Salma Tuna Butt, Signe Borgquist, Karin Elebro, Malte Sandsveden, Jonas Manjer, Ann Rosendahl
Summary: This study found no association between pre-diagnostic levels of vitamin D and the expression of VDRs in breast cancer, nor did vitamin D levels influence the association between VDR expression and breast cancer mortality.
Article
Endocrinology & Metabolism
Zhongyu Jian, Yu Huang, Yazhou He, Xi Jin, Hong Li, Sheyu Li, Kunjie Wang
Summary: The study found that higher genetically predicted lifelong circulating 25(OH)D levels are associated with higher calcium levels and KSD risk. The effects of 25(OH)D on KSD were partially attenuated but still significant in MVMR.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Oncology
Jian Zhou, Xianxiu Ge, Xikang Fan, Jiayu Wang, Lin Miao, Dong Hang
Summary: Research from UK Biobank showed that higher concentrations of serum 25(OH)D are associated with decreased incidence and improved survival of colorectal cancer.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Nutrition & Dietetics
Laila Meija, Anna Piskurjova, Ksenija Nikolajeva, Olga Aizbalte, Roberta Rezgale, Aivars Lejnieks, Vinita Cauce
Summary: This cross-sectional study in Latvia evaluated the vitamin D levels and intake of pregnant women. The results showed that a minority of pregnant women had sufficient vitamin D, and diet did not significantly affect vitamin D levels. Therefore, a recommended daily intake of 63 mcg (2500 IU) of vitamin D during pregnancy is proposed to maintain optimal levels.
Article
Medicine, General & Internal
Li-liangzi Guo, Si-si Chen, Li-xian Zhong, Kai-yin He, Yu-ting Li, Wei-wei Chen, Qiu-ting Zeng, Shao-hui Tang
Summary: The consumption of vitamin D and the circulating level of 25(OH)D are associated with a decreased risk of CRC precursors. However, they do not significantly affect the risk of recurrence of CRC precursors.
FRONTIERS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Carolina Morgado-Aguila, Guadalupe Gil-Fernandez, Orlando Rafael Davila-Villalobos, Jesus Perez-Rey, Purificacion Rey-Sanchez, Francisco Jose Rodriguez-Velasco
Summary: This study investigated the association between serum vitamin D levels and non-melanoma skin cancers. Despite all subjects having normal or low levels of vitamin D, it was found that higher vitamin D levels may increase the risk of non-melanoma skin cancer. Further research is needed to fully understand the relationship between vitamin D and skin cancer risk.
Article
Nutrition & Dietetics
Peng-Peng Niu, Xue Wang, Yu-Ming Xu
Summary: This study using two-sample Mendelian randomization (MR) found that genetically determined increased circulating vitamin D levels are associated with decreased migraine risk. The effect seems consistent across different migraine subtypes. The role of serum calcium in mediating the association between vitamin D and migraine is negligible.
FRONTIERS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Wei Fun Cheong, Shanshan Ji, Amaury Cazenave-Gassiot, Win Pa Pa Thu, Susan Logan, Jane Cauley, Michael S. Kramer, Eu-Leong Yong
Summary: Vitamin D levels were found to be lowest in Indian and Malay women compared to Chinese women, as well as in younger and employed women in Singapore. Deficient cutaneous production was identified as the main reason for hypovitaminosis D in study women. Ethnicity and opportunities for sunlight exposure should be considered in supplementation efforts in regions with abundant sunshine.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Nutrition & Dietetics
Shengyi Yang, Hong Zhi, Ying Sun, Lina Wang
Summary: The aim of this study was to evaluate the association between serum vitamin D levels and atrial fibrillation (AF) risks using two-sample Mendelian randomization (MR) analysis. The results showed no causal association between genetically predicted vitamin D levels and AF risk. Further research is needed to explore the potential role and mechanisms of circulating serum vitamin D levels on AF.
FRONTIERS IN NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Xin Zhang, Yu-Jing Fang, Xiao-Li Feng, Alinuer Abulimiti, Chu-Yi Huang, Hong Luo, Cai-Xia Zhang
Summary: This study found a significant reduction in colorectal cancer risk associated with higher intakes of dietary vitamin D and calcium, as well as a significant interaction between dietary vitamin D intake and Apa I polymorphisms. However, no significant associations were found between Fok I, Bsm I, and Taq I and colorectal cancer risk.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Nutrition & Dietetics
Ilham Lhilali, Noura Zouine, Aziza Menouni, Lode Godderis, Marie-Paule Kestemont, Adil El Midaoui, Samir El Jaafari, Younes Filali-Zegzouti
Summary: This study developed and validated a sun exposure score (SES) and found a significant correlation between SES and serum 25-hydroxyvitamin D levels in women of childbearing age. The results suggest that the SES could be used as a clinical tool to assess vitamin D levels in this population.
Review
Food Science & Technology
Lu Yang, Hang Zhao, Ke Liu, Yichao Wang, Qianqian Liu, Tiantian Sun, Shuchun Chen, Luping Ren
Summary: This meta-analysis revealed that smokers have lower circulating vitamin D levels compared to nonsmokers, regardless of vitamin D supplement use. Subgroup analysis based on age showed that smokers in each age subgroup had lower serum 25(OH)D levels than the control group.
FOOD SCIENCE & NUTRITION
(2021)