Vesicle Induced Receptor Sequestration: Mechanisms behind Extracellular Vesicle‐Based Protein Signaling

Bottom-up assembly of biomedical relevant fully synthetic extracellular vesicles

(2021) Oskar Staufer et al.   Science Advances

Bottom‐Up Assembly of Functional Intracellular Synthetic Organelles by Droplet‐Based Microfluidics

(2020) Oskar Staufer et al.   Small

Impact of isolation methods on the biophysical heterogeneity of single extracellular vesicles

(2020) Shivani Sharma et al.   Scientific Reports

Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery

(2020) Oskar Staufer et al.   BIOMATERIALS

Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared to recombinant IL-12

(2020) Nuruddeen D. Lewis et al.   MOLECULAR CANCER THERAPEUTICS

Mechanisms of intercellular Wnt transport

(2019) Daniel Routledge et al.   DEVELOPMENT

One-Pot Assembly of Complex Giant Unilamellar Vesicle-Based Synthetic Cells

(2019) Kerstin Göpfrich et al.   ACS Synthetic Biology

The biology of extracellular vesicles: The known unknowns

(2019) Leonid Margolis et al.   PLOS BIOLOGY

The role of exosomal PD-L1 in tumor progression and immunotherapy

(2019) Feiting Xie et al.   Molecular Cancer

Bottom-up synthetic biology: reconstitution in space and time

(2019) Haiyang Jia et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biophysical properties of extracellular vesicles in diagnostics

(2018) Lucia Paolini et al.   Biomarkers in Medicine

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protease-resistant cell meshworks: An indication of membrane nanotube-based syncytia formation

(2018) Oskar Staufer et al.   EXPERIMENTAL CELL RESEARCH

Charge-controlled microfluidic formation of lipid-based single- and multicompartment systems

(2018) Barbara Haller et al.   LAB ON A CHIP

Coupling of bone resorption and formation by RANKL reverse signalling

(2018) Yuki Ikebuchi et al.   NATURE

Osteoclast regulation of osteoblasts via RANK-RANKL reverse signal transduction in vitro

(2017) Shiqian Zhang et al.   Molecular Medicine Reports

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

(2017) Sybren L.N. Maas et al.   TRENDS IN CELL BIOLOGY

A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage

(2017) Katharina Niopek et al.   Cell Reports

Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation

(2016) Kyunghee Lee et al.   International Journal of Biological Sciences

Mechanisms and functions of extracellular vesicle release in vivo—What we can learn from flies and worms

(2016) Katharina B. Beer et al.   Cell Adhesion & Migration

Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein

(2016) Alberto Bosque et al.   Oncotarget

Agonist mobility on supported lipid bilayers affects Fas mediated death response

(2015) M. Florencia Sánchez et al.   FEBS LETTERS

Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium

(2015) H Matsumoto et al.   Cell Death & Disease

Principles and mechanisms of CD95 activation

(2014) Harald Wajant   BIOLOGICAL CHEMISTRY

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Molecular architecture of the αβ T cell receptor–CD3 complex

(2014) Michael E. Birnbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis

(2014) S. M. Kallenberger et al.   Science Signaling

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus

(2013) L. Bossaller et al.   JOURNAL OF IMMUNOLOGY

Exosomes Secreted by Human Placenta Carry Functional Fas Ligand and TRAIL Molecules and Convey Apoptosis in Activated Immune Cells, Suggesting Exosome-Mediated Immune Privilege of the Fetus

(2013) A.-C. Stenqvist et al.   JOURNAL OF IMMUNOLOGY

Synthesis of Nanostructured and Biofunctionalized Water-in-Oil Droplets as Tools for Homing T Cells

(2013) Ilia Platzman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional Characterization of a Chimeric Soluble Fas Ligand Polymer with In Vivo Anti-Tumor Activity

(2013) Sophie Daburon et al.   PLoS One

Generation of Soluble NKG2D Ligands: Proteolytic Cleavage, Exosome Secretion and Functional Implications

(2013) G. Chitadze et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Dual effects of soluble FasL and membrane bound FasL on fibroblast-like synoviocytes cells from rheumatoid arthritis patients

(2012) Rachel Audo et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting the Fas/FasL signaling pathway in cancer therapy

(2012) María Villa-Morales et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Transfer of extracellular vesicles during immune cell-cell interactions

(2012) Cristina Gutiérrez-Vázquez et al.   IMMUNOLOGICAL REVIEWS

Signaling Active CD95 Receptor Molecules Trigger Co-translocation of Inactive CD95 Molecules into Lipid Rafts

(2012) Isabell Lang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adhesion of membranes via receptor–ligand complexes: Domain formation, binding cooperativity, and active processes

(2009) Thomas R. Weikl et al.   Soft Matter