Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners

(2022) Anne-Sophie Archambault et al.   Cells

Omega‐3 fatty acids protect from colitis via an Alox15‐derived eicosanoid

(2021) Nadine Rohwer et al.   FASEB JOURNAL

Stereoselective Synthesis and Structural Confirmation of the Specialized Pro-Resolving Mediator Resolvin E4

(2021) Amalie Føreid Reinertsen et al.   JOURNAL OF ORGANIC CHEMISTRY

12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice

(2021) Jun Miyata et al.   Frontiers in Immunology

Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases

(2021) Anne V. Lyngstadaas et al.   Frontiers in Immunology

Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19

(2021) Duco Steven Koenis et al.   CIRCULATION RESEARCH

Quantitative profiling of inflammatory and pro-resolving lipid mediators in human adolescents and mouse plasma using UHPLC-MS/MS

(2021) Ivan Hartling et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

High levels of eicosanoids and docosanoids in the lungs of intubated COVID‐19 patients

(2021) Anne‐Sophie Archambault et al.   FASEB JOURNAL

Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5−/− Mice

(2021) Eugenia Marbach-Breitrück et al.   Metabolites

On the biosynthesis of specialized pro-resolving mediators in human neutrophils and the influence of cell integrity

(2021) Malwina Mainka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis

(2020) Markus Werner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effects of chronic low‐dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis

(2020) Nadine Rohwer et al.   Cancer Medicine

Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages

(2020) Roland Ebert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Toll-like receptor signaling induces a temporal switch towards a resolving lipid profile in monocyte-derived macrophages

(2020) Johannes H. von Hegedus et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dual modulation of formyl peptide receptor 2 by aspirin‐triggered lipoxin contributes to its anti‐inflammatory activity

(2020) Yunjun Ge et al.   FASEB JOURNAL

15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-Lipoxygenase-2 in biosynthesis of resolvin D5

(2020) Steven C Perry et al.   JOURNAL OF LIPID RESEARCH

Eosinophils promote corneal wound healing via the 12/15‐lipoxygenase pathway

(2020) Mamoru Ogawa et al.   FASEB JOURNAL

Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18

(2020) Clara T. Schoeder et al.   ACS Medicinal Chemistry Letters

A rapid and high-throughput approach to quantify non-esterified oxylipins for epidemiological studies using online SPE-LC-MS/MS

(2020) Teng Wang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1

(2020) Steven C. Perry et al.   BIOCHEMISTRY

Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution

(2020) Paul M. Jordan et al.   Cell Reports

Plasma and serum oxylipin, endocannabinoid, bile acid, steroid, fatty acid and nonsteroidal anti-inflammatory drug quantification in a 96-well plate format

(2020) Theresa L. Pedersen et al.   ANALYTICA CHIMICA ACTA

Human lipoxygenase isoforms form complex patterns of double and triple oxygenated compounds from eicosapentaenoic acid

(2020) Laura Kutzner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis

(2019) Ragnar P. Kristjansson et al.   NATURE GENETICS

Development of an Optimized LC-MS Method for the Detection of Specialized Pro-Resolving Mediators in Biological Samples

(2019) Laura Kutzner et al.   Frontiers in Pharmacology

Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome

(2019) Markus Werner et al.   FASEB JOURNAL

Plasma oxylipins respond in a linear dose-response manner with increased intake of EPA and DHA: results from a randomized controlled trial in healthy humans

(2019) Annika I Ostermann et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities

(2019) Cécile Gladine et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity

(2019) Keith Allen-Redpath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation

(2019) Zhigang Rao et al.   JOURNAL OF IMMUNOLOGY

Knockout of ALOX12 protects against spinal cord injury-mediated nerve injury by inhibition of inflammation and apoptosis

(2019) Ji-Li Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

(2019) Simon R. Foster et al.   CELL

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolution metabolomes activated by hypoxic environment

(2019) Paul C. Norris et al.   Science Advances

GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections

(2019) Magdalena B. Flak et al.   JOURNAL OF CLINICAL INVESTIGATION

Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry

(2018) Andy Toewe et al.   ANALYTICA CHIMICA ACTA

The G protein-coupled receptors deorphanization landscape

(2018) Céline Laschet et al.   BIOCHEMICAL PHARMACOLOGY

Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function

(2018) Saskia Kroschwald et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ERV1/ChemR23 Signaling Protects from Atherosclerosis by Modifying oxLDL Uptake and Phagocytosis in Macrophages

(2018) Andres Laguna-Fernandez et al.   CIRCULATION

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue

(2018) Heike Gottschall et al.   JOURNAL OF LIPID RESEARCH

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Comprehensive analysis of the mouse cytochrome P450 family responsible for omega-3 epoxidation of eicosapentaenoic acid

(2018) Yosuke Isobe et al.   Scientific Reports

Lipidomic profiling of targeted oxylipins with ultra-performance liquid chromatography-tandem mass spectrometry

(2018) Zhi-Xin Yuan et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The atheroprotective role of lipoxin A4 prevents oxLDL-induced apoptotic signaling in macrophages via JNK pathway

(2018) Jingting Mai et al.   ATHEROSCLEROSIS

The therapeutic effects of lipoxin A4 during treadmill exercise on monosodium iodoacetate-induced osteoarthritis in rats

(2018) Yue Yang et al.   MOLECULAR IMMUNOLOGY

Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

(2018) Anne-Sophie Archambault et al.   PLoS One

5S,15S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1

(2018) Abigail R. Green et al.   BIOCHEMISTRY

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

(2017) Charles N. Serhan   FASEB JOURNAL

Maresin1 stimulates alveolar fluid clearance through the alveolar epithelial sodium channel Na,K-ATPase via the ALX/PI3K/Nedd4-2 pathway

(2017) Jun-Li Zhang et al.   LABORATORY INVESTIGATION

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology

(2017) Charles N. Serhan   MOLECULAR ASPECTS OF MEDICINE

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas

(2017) Veronika Fedirko et al.   MOLECULAR CARCINOGENESIS

The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition

(2017) Hui-Qiong He et al.   MOLECULES

Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans

(2017) H.S. Jónasdóttir et al.   OSTEOARTHRITIS AND CARTILAGE

Targeting 12-Lipoxygenase as a Potential Novel Antiplatelet Therapy

(2017) Benjamin E. Tourdot et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential

(2016) Abigail R. Green et al.   BIOCHEMISTRY

Formyl-Peptide Receptor 2/3/Lipoxin A4Receptor Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral InflammationCLINICAL PERSPECTIVE

(2016) Shantel A. Vital et al.   CIRCULATION

Novel Resolvin D2 Receptor Axis in Infectious Inflammation

(2016) Nan Chiang et al.   JOURNAL OF IMMUNOLOGY

Lipoxin A4 activates ALX/FPR2 receptor to regulate conjunctival goblet cell secretion

(2016) R R Hodges et al.   Mucosal Immunology

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

(2016) Gabrielle Fredman et al.   Nature Communications

Targeted metabolomics of the arachidonic acid cascade: current state and challenges of LC–MS analysis of oxylipins

(2015) Ina Willenberg et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Differential Mobility Separation of Leukotrienes and Protectins

(2015) Hulda S. Jónasdóttir et al.   ANALYTICAL CHEMISTRY

Development and Validation of a High-Throughput Ultrahigh-Performance Liquid Chromatography–Mass Spectrometry Approach for Screening of Oxylipins and Their Precursors

(2015) Arnaud M. Wolfer et al.   ANALYTICAL CHEMISTRY

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

(2015) Christoph Lehmann et al.   FASEB JOURNAL

Identification of resolvin D2 receptor mediating resolution of infections and organ protection

(2015) Nan Chiang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bioactive products formed in humans from fish oils

(2015) Carsten Skarke et al.   JOURNAL OF LIPID RESEARCH

The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer’s disease phenotype

(2015) Yash B. Joshi et al.   Frontiers in Cellular Neuroscience

Nano-LC in proteomics: recent advances and approaches

(2015) Steven Ray Wilson et al.   Bioanalysis

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

(2014) Romain A. Colas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Comparison of sample preparation methods for the quantitative analysis of eicosanoids and other oxylipins in plasma by means of LC-MS/MS

(2014) Annika I. Ostermann et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lipoxin A4suppresses the development of endometriosis in an ALX receptor-dependent manner via the p38 MAPK pathway

(2014) Rongfeng Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

An Advanced LC–MS/MS Platform for the Analysis of Specialized Pro-Resolving Lipid Mediators

(2014) Hulda S. Jónasdóttir et al.   CHROMATOGRAPHIA

Current development in non-enzymatic lipid peroxidation products, isoprostanoids and isofuranoids, in novel biological samples

(2014) K. S. Leung et al.   FREE RADICAL RESEARCH

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway

(2014) Robert Fischer et al.   JOURNAL OF LIPID RESEARCH

Lipoxin A4: Problems with its determination using reversed phase chromatography–tandem mass spectrometry and confirmation with chiral chromatography

(2014) Nerea Ferreirós et al.   TALANTA

Pivotal Role of 5-Lipoxygenase Pathway in Lung Injury After Experimental Sepsis

(2013) Ana Paula T Monteiro et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Heterologously expressed formyl peptide receptor 2 (FPR2/ALX) does not respond to lipoxin A4

(2013) Julien Hanson et al.   BIOCHEMICAL PHARMACOLOGY

Resolvin D1-mediated NOX2 inactivation rescues macrophages undertaking efferocytosis from oxidative stress-induced apoptosis

(2013) Ha-Na Lee et al.   BIOCHEMICAL PHARMACOLOGY

A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation

(2013) V. Brancaleone et al.   BLOOD

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY

Lack of activity of 15-epi-lipoxin A4on FPR2/ALX and CysLT1 receptors in interleukin-8-driven human neutrophil function

(2013) A. Planagumà et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Critical Role of 5-Lipoxygenase and Heme Oxygenase-1 in Wound Healing

(2013) Ariane R. Brogliato et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma

(2013) C. Barnig et al.   Science Translational Medicine

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

(2012) Sriram Krishnamoorthy et al.   AMERICAN JOURNAL OF PATHOLOGY

The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis

(2012) Gerhard Krönke et al.   ANNALS OF THE RHEUMATIC DISEASES

Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

(2012) Lucy V. Norling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expression and regulation of 12/15-lipoxygenases in human primary macrophages

(2012) Sophia J.A. Wuest et al.   ATHEROSCLEROSIS

Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS

(2012) Martin Giera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

(2012) J. Dalli et al.   BLOOD

Resolvins D1, D2, and Other Mediators of Self-Limited Resolution of Inflammation in Human Blood following n-3 Fatty Acid Supplementation

(2012) E. Mas et al.   CLINICAL CHEMISTRY

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

(2012) Yosuke Isobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resolvin E2 Formation and Impact in Inflammation Resolution

(2012) S. F. Oh et al.   JOURNAL OF IMMUNOLOGY

Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis

(2012) Shunxing Rong et al.   JOURNAL OF LIPID RESEARCH

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

5-Lipoxygenase Deficiency Impairs Innate and Adaptive Immune Responses during Fungal Infection

(2012) Adriana Secatto et al.   PLoS One

Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor

(2012) F. A. Pamplona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of gestational hypercholesterolemia and maternal immunization on offspring plasma eicosanoids

(2011) Oswald Quehenberger et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines

(2011) Darren S. Dumlao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

(2011) Douglas McHugh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipoxin A4 is a novel estrogen receptor modulator

(2011) Ronan Russell et al.   FASEB JOURNAL

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

What Formyl Peptide Receptors, if Any, Are Triggered by Compound 43 and Lipoxin A4 ?

(2011) H. Forsman et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

(2010) Douglas McHugh et al.   BMC NEUROSCIENCE

The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease

(2010) D. Poeckel et al.   CARDIOVASCULAR RESEARCH

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis

(2010) Paola Maderna et al.   FASEB JOURNAL

Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease

(2010) Marcos Martínez-Clemente et al.   HEPATOLOGY

Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses

(2010) K. Chen et al.   JOURNAL OF IMMUNOLOGY

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

(2010) Neil Dufton et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

(2009) Jun Yang et al.   ANALYTICAL CHEMISTRY

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

(2009) Tatjana Haitina et al.   BMC GENOMICS

Lipid G Protein-coupled Receptor Ligand Identification Using β-Arrestin PathHunter™ Assay

(2009) Hong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

(2009) G. Kronke et al.   JOURNAL OF IMMUNOLOGY

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

(2009) Matthew Spite et al.   NATURE

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice

(2009) Dorothy D. Sears et al.   PLoS One

Lipoxin A4Metabolites/Analogues from Two Commercial Sources have No Effects on TNF-α-mediated Priming or Activation through the Neutrophil Formyl Peptide Receptors

(2009) H. Forsman et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Mice Lacking 12/15-Lipoxygenase Have Attenuated Airway Allergic Inflammation and Remodeling

(2008) Cecilia K. Andersson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

(2008) Aksam J. Merched et al.   FASEB JOURNAL