Changes inO-LinkedN-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells

O-GlcNAc protein modification in C2C12 myoblasts exposed to oxidative stress indicates parallels with endogenous antioxidant defense

(2015) Tina Tinkara Peternelj et al.   Biochemistry and Cell Biology

Cell death decision by p53 via control of the mitochondrial membrane

(2015) Nurmaa Dashzeveg et al.   CANCER LETTERS

p53: Protection against Tumor Growth beyond Effects on Cell Cycle and Apoptosis

(2015) X. Wang et al.   CANCER RESEARCH

A little sugar goes a long way: The cell biology of O-GlcNAc

(2015) Michelle R. Bond et al.   JOURNAL OF CELL BIOLOGY

Quantitative phosphoproteomics reveals crosstalk between phosphorylation andO-GlcNAc in the DNA damage response pathway

(2015) Jun Zhong et al.   PROTEOMICS

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer

(2015) Andréia Vasconcelos-dos-Santos et al.   Frontiers in Oncology

Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway

(2015) Erli Zhang et al.   PLoS One

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

(2015) Xuan Zhang et al.   Oncotarget

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

(2014) Patricia A.J. Muller et al.   CANCER CELL

Apoptosis-Inducing Effects ofMelissa officinalisL. Essential Oil in Glioblastoma Multiforme Cells

(2014) Rafaela Muniz de Queiroz et al.   CANCER INVESTIGATION

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

Glutathione depletion and acute exercise increase O-GlcNAc protein modification in rat skeletal muscle

(2014) Tina Tinkara Peternelj et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Identification of O-GlcNAc Modification Targets in Mouse Retinal Pericytes: Implication of p53 in Pathogenesis of Diabetic Retinopathy

(2014) Zafer Gurel et al.   PLoS One

O-GlcNAcylation: The Sweet Side of the Cancer

(2014) Rafaela Muniz de Queiroz et al.   Frontiers in Oncology

O-GlcNAc in cancer biology

(2013) Zhiyuan Ma et al.   AMINO ACIDS

Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer

(2013) Tom Van Maerken et al.   CANCER LETTERS

O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

(2013) H. M. Itkonen et al.   CANCER RESEARCH

Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis

(2013) Jennifer A. Groves et al.   CELL STRESS & CHAPERONES

Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research

(2013) Michael S. Anglesio et al.   PLoS One

O-GlcNAcylation of kinases

(2012) Wagner B. Dias et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surf the Post-translational Modification Network of p53 Regulation

(2012) Bo Gu et al.   International Journal of Biological Sciences

Critical Role ofO-Linked β-N-Acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis

(2012) Thomas P. Lynch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

(2011) Wenyi Mi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Deconstructing p53 transcriptional networks in tumor suppression

(2011) Kathryn T. Bieging et al.   TRENDS IN CELL BIOLOGY

Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice

(2010) Susan A. Marsh et al.   AMINO ACIDS

Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis

(2010) Matthew S. Macauley et al.   CHEMISTRY & BIOLOGY

Elevation of nucleocytoplasmic β-N-acetylglucosaminidase (O-GlcNAcase) activity in thyroid cancers

(2010) Krzeslak   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

(2010) Y Shi et al.   LEUKEMIA

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Calcium/Calmodulin-dependent Kinase IV byO-GlcNAc Modification

(2009) Wagner B. Dias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY