RANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice

Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency

(2016) Asuka Terashima et al.   IMMUNITY

Targeting of Mesenchymal Stromal Cells byCre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells

(2016) Jingzhu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Activation of mTORC1 in B Lymphocytes Promotes Osteoclast Formation via Regulation of β-Catenin and RANKL/OPG

(2016) Song Xu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

(2015) Jinhu Xiong et al.   PLoS One

Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency

(2014) Jinhu Xiong et al.   BONE

Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development

(2014) Toshihide Mizoguchi et al.   DEVELOPMENTAL CELL

Inhibition of Bone Remodeling in Young Mice by Bisphosphonate Displaces the Plasma Cell Niche into the Spleen

(2014) S. Teufel et al.   JOURNAL OF IMMUNOLOGY

Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice

(2013) Shino Kondoh et al.   BONE

The Osteocyte: An Endocrine Cell … and More

(2013) Sarah L. Dallas et al.   ENDOCRINE REVIEWS

Steap4 Plays a Critical Role in Osteoclastogenesisin Vitroby Regulating Cellular Iron/Reactive Oxygen Species (ROS) Levels and cAMP Response Element-binding Protein (CREB) Activation

(2013) Jian Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

The role of estrogen and androgen receptors in bone health and disease

(2013) Stavros C. Manolagas et al.   Nature Reviews Endocrinology

Estrogen receptor-  in osteocytes is important for trabecular bone formation in male mice

(2013) S. H. Windahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor Activator of Nuclear Factor κB Ligand (RANKL) Protein Expression by B Lymphocytes Contributes to Ovariectomy-induced Bone Loss

(2012) Melda Onal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Development and Function of Murine B Cells Lacking RANK

(2012) T. Perlot et al.   JOURNAL OF IMMUNOLOGY

Osteoclast activity modulates B-cell development in the bone marrow

(2011) Anna Mansour et al.   CELL RESEARCH

B-1 lymphocytes differentiate into functional osteoclast-like cells

(2011) Livia Souza Pugliese et al.   IMMUNOBIOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone

(2010) Marta Martin-Millan et al.   MOLECULAR ENDOCRINOLOGY

Increased RANK ligand in bone marrow of orchiectomized rats and prevention of their bone loss by the RANK ligand inhibitor osteoprotegerin

(2009) Xiaodong Li et al.   BONE

Orchiectomy upregulates free soluble RANKL in bone marrow of aged rats

(2009) Verena Proell et al.   BONE

Control of RANKL gene expression

(2009) Charles A. O'Brien   BONE

Effects of oral and transdermal estrogen therapies on circulating cytokines and chemokines in postmenopausal women with hysterectomy

(2009) Toshiyuki Yasui et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women

(2008) Toshiyuki Yasui et al.   ATHEROSCLEROSIS

Osteoblastic regulation of B lymphopoiesis is mediated by Gs -dependent signaling pathways

(2008) J. Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA