Using a Genetically Encoded Sensor to Identify Inhibitors ofToxoplasma gondiiCa2+Signaling

Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites

(2015) Brittany L. Howard et al.   ACS Chemical Biology

Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans

(2015) Aditya S. Paul et al.   Cell Host & Microbe

Calcium Signaling throughout theToxoplasma gondiiLytic Cycle

(2015) Lucas Borges-Pereira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive characterization of the Published Kinase Inhibitor Set

(2015) Jonathan M Elkins et al.   NATURE BIOTECHNOLOGY

Calcium storage and function in apicomplexan parasites: Figure 1

(2015) Silvia N.J. Moreno et al.   Essays in Biochemistry

Calcium Entry inToxoplasma gondiiand Its Enhancing Effect of Invasion-linked Traits

(2014) Douglas A. Pace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Genome Engineering of Toxoplasma gondii Using CRISPR/Cas9

(2014) Saima M. Sidik et al.   PLoS One

Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca2+ Signals at Key Decision Points in the Life Cycle of Malaria Parasites

(2014) Mathieu Brochet et al.   PLOS BIOLOGY

Phenotypic screens as a renewed approach for drug discovery

(2013) Wei Zheng et al.   DRUG DISCOVERY TODAY

Optimizing Small Molecule Inhibitors of Calcium-Dependent Protein Kinase 1 to Prevent Infection by Toxoplasma gondii

(2013) Sebastian Lourido et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cytoplasmic free Ca2+ is essential for multiple steps in malaria parasite egress from infected erythrocytes

(2013) Svetlana Glushakova et al.   MALARIA JOURNAL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Endoplasmic Reticulum Structure and Interconnections with Other Organelles

(2013) A. R. English et al.   Cold Spring Harbor Perspectives in Biology

Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress

(2013) Christine R. Collins et al.   PLoS Pathogens

Distinct signalling pathways controlToxoplasmaegress and host-cell invasion

(2012) Sebastian Lourido et al.   EMBO JOURNAL

Development of Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitors with Potent Anti-Toxoplasma Activity

(2012) Steven M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A Major Genome Region Underlying Artemisinin Resistance in Malaria

(2012) I. H. Cheeseman et al.   SCIENCE

A DOC2 Protein Identified by Mutational Profiling Is Essential for Apicomplexan Parasite Exocytosis

(2012) A. Farrell et al.   SCIENCE

Characterization of the cellular action of the MSK inhibitor SB-747651A

(2011) Shaista Naqvi et al.   BIOCHEMICAL JOURNAL

Toxoplasma and Plasmodium protein kinases: Roles in invasion and host cell remodelling

(2011) Daniel C. Lim et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

An Expanded Palette of Genetically Encoded Ca2+ Indicators

(2011) Y. Zhao et al.   SCIENCE

A flow cytometry-based assay for measuring invasion of red blood cells byPlasmodium falciparum

(2010) Amy K. Bei et al.   AMERICAN JOURNAL OF HEMATOLOGY

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

(2010) M. J. Boyle et al.   BLOOD

Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole

(2010) Kildare Miranda et al.   MOLECULAR MICROBIOLOGY

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

(2010) Shailja Singh et al.   PLoS Pathogens

Calcium-Dependent Signaling and Kinases in Apicomplexan Parasites

(2009) Oliver Billker et al.   Cell Host & Microbe

The Malaria Parasite Cyclic GMP-Dependent Protein Kinase Plays a Central Role in Blood-Stage Schizogony

(2009) Helen M. Taylor et al.   EUKARYOTIC CELL

Development of a Fluorescent-Tagged Kinase Assay System for the Detection and Characterization of Allosteric Kinase Inhibitors

(2009) Jeffrey R. Simard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors

(2008) Kirk L. Stevens et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Malarial proteases and host cell egress: an ‘emerging’ cascade

(2008) Michael J. Blackman   CELLULAR MICROBIOLOGY

Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells

(2008) B. F. C. Kafsack et al.   SCIENCE