Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions

Efficient inhibition of infectious prions multiplication and release by targeting the exosomal pathway

(2015) Didier Vilette et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes

(2014) Belinda B. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties

(2013) Enrico Cancellotti et al.   EMBO JOURNAL

Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

(2012) Bradley M. Coleman et al.   FASEB JOURNAL

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

(2012) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

(2012) Shayne A. Bellingham et al.   Frontiers in Physiology

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

(2011) Lydia Alvarez-Erviti et al.   NEUROBIOLOGY OF DISEASE

Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity

(2010) Christopher F. Harrison et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylation of PrPC Determines Timing of Neuroinvasion and Targeting in the Brain following Transmissible Spongiform Encephalopathy Infection by a Peripheral Route

(2010) E. Cancellotti et al.   JOURNAL OF VIROLOGY

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

(2008) N. Izquierdo-Useros et al.   BLOOD

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL

Mouse-adapted sporadic human Creutzfeldt–Jakob disease prions propagate in cell culture

(2008) Victoria A. Lawson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants

(2008) Réjean Cantin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Exosomes Secreted by Bacterially Infected Macrophages Are Proinflammatory

(2008) H. C. O'Neill et al.   Science Signaling

Role of Endoplasmic Reticulum, Endosomal-Lysosomal Compartments, and Microtubules in Amyloid Precursor Protein Metabolism of Human Neurons

(2003) Andréa C. LeBlanc et al.   JOURNAL OF NEUROCHEMISTRY