Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α

The glucocorticoid receptor: cause of or cure for obesity?

(2016) Kezia John et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation

(2016) Tihomir Miralem et al.   FASEB JOURNAL

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

(2016) David E. Stec et al.   PLoS One

Biliverdin reductase isozymes in metabolism

(2015) Luke O’Brien et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice

(2014) Yi Yang et al.   ACTA PHARMACOLOGICA SINICA

Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice

(2014) Nicole S. Banko et al.   AMERICAN JOURNAL OF PATHOLOGY

Unconjugated Bilirubin Mediates Heme Oxygenase-1–Induced Vascular Benefits in Diabetic Mice

(2014) Jian Liu et al.   DIABETES

Human biliverdin reductase-based peptides activate and inhibit glucose uptake through direct interaction with the kinase domain of insulin receptor

(2014) Peter E. M. Gibbs et al.   FASEB JOURNAL

Anti-obesity effects of 3-hydroxychromone derivative, a novel small-molecule inhibitor of glycogen synthase kinase-3

(2013) Sooho Lee et al.   BIOCHEMICAL PHARMACOLOGY

Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice

(2013) Valérie Lebrun et al.   CLINICAL SCIENCE

Scutellarin from Scutellaria baicalensis Suppresses Adipogenesis by Upregulating PPARα in 3T3-L1 Cells

(2013) Kaihui Lu et al.   JOURNAL OF NATURAL PRODUCTS

Serum Bilirubin Level Is Inversely Associated With Nonalcoholic Steatohepatitis in Children

(2013) Kanika Puri et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21

(2013) Terry D. Hinds et al.   Obesity

Chronic HO-1 induction with cobalt protoporphyrin (CoPP) treatment increases oxygen consumption, activity, heat production and lowers body weight in obese melanocortin-4 receptor-deficient mice

(2011) E Csongradi et al.   INTERNATIONAL JOURNAL OF OBESITY

Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-γ (PPARγ)

(2011) Terry D. Hinds et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes

(2011) Tsuyoshi Goto et al.   JOURNAL OF LIPID RESEARCH

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

(2010) Yung-Sheng Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis

(2010) Samar H. Ibrahim et al.   JOURNAL OF HEPATOLOGY

Discovery of Glucocorticoid Receptor-β in Mice with a Role in Metabolism

(2010) Terry D. Hinds et al.   MOLECULAR ENDOCRINOLOGY

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

(2009) Eric D. Berglund et al.   ENDOCRINOLOGY

Multiple signalling pathways redundantly control glucose transporterGLUT4gene transcription in skeletal muscle

(2009) Marta Murgia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Valproate Attenuates Accelerated Atherosclerosis in Hyperglycemic ApoE-Deficient Mice

(2008) Anna J. Bowes et al.   AMERICAN JOURNAL OF PATHOLOGY

Crucial role for LKB1 to AMPKα2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes☆

(2008) Daphna D.J. Habets et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inhibition of GLUT4 Translocation by Tbc1d1, a Rab GTPase-activating Protein Abundant in Skeletal Muscle, Is Partially Relieved by AMP-activated Protein Kinase Activation

(2008) Jose A. Chavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biliverdin Reductase Mediates Hypoxia-Induced EMT via PI3-Kinase and Akt

(2008) R. Zeng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling

(2008) N. Lerner-Marmarosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA