Distinct Membrane Disruption Pathways Are Induced by 40-Residue β-Amyloid Peptides

Competition between Fibrillation and Induction of Vesicle Fusion for the Membrane-Associated 40-Residue β-Amyloid Peptides

(2015) Rumonat D. Akinlolu et al.   BIOCHEMISTRY

Fibrillation of β amyloid peptides in the presence of phospholipid bilayers and the consequent membrane disruption

(2015) Wei Qiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Successive Stages of Amyloid-β Self-Assembly Characterized by Solid-State Nuclear Magnetic Resonance with Dynamic Nuclear Polarization

(2015) Alexey Potapov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Evolution and Membrane Interaction of the 40-Residue β Amyloid Peptides: Differences in the Initial Proximity between Peptides and the Membrane Bilayer Studied by Solid-State Nuclear Magnetic Resonance Spectroscopy

(2014) Wei Qiang et al.   BIOCHEMISTRY

Membrane fusion and vesicular transformation induced by Alzheimer's amyloid beta

(2013) Mun'delanji C. Vestergaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Polymorph-Specific Kinetics and Thermodynamics of β-Amyloid Fibril Growth

(2013) Wei Qiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular interactions of Alzheimer amyloid-β oligomers with neutral and negatively charged lipid bilayers

(2013) Xiang Yu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Effects of Point Substitutions on the Structure of Toxic Alzheimer’s β-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations

(2012) Laura Connelly et al.   BIOCHEMISTRY

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

NMR Determination of Protein Partitioning into Membrane Domains with Different Curvatures and Application to the Influenza M2 Peptide

(2012) Tuo Wang et al.   BIOPHYSICAL JOURNAL

All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers

(2012) Ricardo Capone et al.   Journal of Chemical Theory and Computation

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Structural Evolution of Iowa Mutant β-Amyloid Fibrils from Polymorphic to Homogeneous States under Repeated Seeded Growth

(2011) Wei Qiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipid Membranes and β-Amyloid: A Harmful Connection

(2010) G.P. Eckert et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Ion channel activity of brain abundant protein BASP1 in planar lipid bilayers

(2010) Olga S. Ostroumova et al.   FEBS Journal

Intrinsic Linear Heterogeneity of Amyloid β Protein Fibrils Revealed by Higher Resolution Mass-per-length Determinations

(2010) Hiroaki Komatsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The interaction of β-amyloid protein fragment (12-28) with lipid environments

(2010) Terry G. Fletcher et al.   PROTEIN SCIENCE

Evidence for Novel β-Sheet Structures in Iowa Mutant β-Amyloid Fibrils

(2009) Robert Tycko et al.   BIOCHEMISTRY

The interaction of beta-amyloid protein with cellular membranes stimulates its own production

(2009) Imke Peters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Solid-state NMR study of membrane interactions of the pore-forming cytolysin, equinatoxin II

(2009) Alison Drechsler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Many Faces of Amyloid β in Alzheimers Disease

(2008) Peter Chiang et al.   CURRENT MOLECULAR MEDICINE

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

(2008) M. F. M. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA