Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition

(2016) Sadeesh K. Ramakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin clearance: an underappreciated modulator of plasma insulin concentration

(2016) Sun H Kim et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance

(2015) Qusai Y. Al-Share et al.   DIABETES

FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

(2014) Sandra Pereira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog

(2013) Marilyn Ader et al.   Obesity

Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: Is that a latent disadvantage?

(2011) Shuai-nan Liu et al.   Journal of Translational Medicine

The Role of Lipid Metabolism in the Pathogenesis of Alcoholic and Nonalcoholic Hepatic Steatosis

(2010) Margaret Sozio et al.   SEMINARS IN LIVER DISEASE

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1: A Link Between Insulin and Lipid Metabolism

(2008) A. M. DeAngelis et al.   DIABETES