Common coupling map advances GPCR-G protein selectivity

Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX

(2022) Peter Kolb et al.   BRITISH JOURNAL OF PHARMACOLOGY

Balanced Expression of G Protein-coupled Receptor Subtypes in the Mouse, Macaque, and Human Cerebral Cortex

(2022) Mario Treviño et al.   NEUROSCIENCE

Noncanonical scaffolding of Gαi and β-arrestin by G protein–coupled receptors

(2021) Jeffrey S. Smith et al.   SCIENCE

Illuminating the complexity of GPCR pathway selectivity – advances in biosensor development

(2021) Shane C. Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The G protein database, GproteinDb

(2021) Gáspár Pándy-Szekeres et al.   NUCLEIC ACIDS RESEARCH

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

(2020) Reid H. J. Olsen et al.   Nature Chemical Biology

Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design

(2020) Marcin Maziarz et al.   CELL

GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells

(2020) Allison Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs

(2020) Eva Marie Pfeil et al.   MOLECULAR CELL

GPCRdb in 2021: integrating GPCR sequence, structure and function

(2020) Albert J Kooistra et al.   NUCLEIC ACIDS RESEARCH

Biased Receptor Signaling in Drug Discovery

(2019) Terry Kenakin   PHARMACOLOGICAL REVIEWS

Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

(2019) Davide Malfacini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Illuminating G-Protein-Coupling Selectivity of GPCRs

(2019) Asuka Inoue et al.   CELL

The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY

(2019) Jane F Armstrong et al.   NUCLEIC ACIDS RESEARCH

Extended Human G-Protein Coupled Receptor Network: Cell-Type-Specific Analysis of G-Protein Coupled Receptor Signaling Pathways

(2019) Avgi E. Apostolakou et al.   JOURNAL OF PROTEOME RESEARCH

Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

(2018) Kelly A Berg et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations

(2018) Srgjan Civciristov et al.   Science Signaling

A Scale of Agonism and Allosteric Modulation for Assessment of Selectivity, Bias, and Receptor Mutation

(2017) Terry Kenakin   MOLECULAR PHARMACOLOGY

Selectivity determinants of GPCR–G-protein binding

(2017) Tilman Flock et al.   NATURE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

The experimental power of FR900359 to study Gq-regulated biological processes

(2015) Ramona Schrage et al.   Nature Communications

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein

(2013) J. Quoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplexing of Multicolor Bioluminescence Resonance Energy Transfer

(2010) Billy Breton et al.   BIOPHYSICAL JOURNAL

Molecular Mechanisms of Go Signaling

(2009) Meisheng Jiang et al.   NEUROSIGNALS