Bone-protective Functions of Netrin 1 Protein

Netrin-1 Is a Critical Autocrine/Paracrine Factor for Osteoclast Differentiation

(2015) Aránzazu Mediero et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo

(2014) Yuichiro Enoki et al.   FEBS LETTERS

Vagus nerve controls resolution and pro-resolving mediators of inflammation

(2014) Valbona Mirakaj et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibitory Immunoglobulin-Like Receptors LILRB and PIR-B Negatively Regulate Osteoclast Development

(2014) Y. Mori et al.   JOURNAL OF IMMUNOLOGY

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity

(2014) Bhama Ramkhelawon et al.   NATURE MEDICINE

The Expression of Netrin-1 in the Thymus and Its Effects on Thymocyte Adhesion and Migration

(2013) Xiao-Kai Guo et al.   Clinical & Developmental Immunology

Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death

(2013) Andrea Paradisi et al.   EMBO Molecular Medicine

Safety concerns with the long-term management of osteoporosis

(2013) Jean-Yves Reginster et al.   Expert Opinion On Drug Safety

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP

(2013) Kenta Maruyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sema3A regulates bone-mass accrual through sensory innervations

(2013) Toru Fukuda et al.   NATURE

The Transcription Factor Jdp2 Controls Bone Homeostasis and Antibacterial Immunity by Regulating Osteoclast and Neutrophil Differentiation

(2012) Kenta Maruyama et al.   IMMUNITY

TRAF Family Member-associated NF-κB Activator (TANK) Is a Negative Regulator of Osteoclastogenesis and Bone Formation

(2012) Kenta Maruyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoprotection by semaphorin 3A

(2012) Mikihito Hayashi et al.   NATURE

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

(2012) Janine M van Gils et al.   NATURE IMMUNOLOGY

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

(2012) Shu Zhu et al.   NATURE MEDICINE

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

(2012) Georg Schett et al.   Nature Reviews Rheumatology

The Monocyte in Atherosclerosis — Should I Stay or Should I Go Now?

(2012) Robert E. Gerszten et al.   NEW ENGLAND JOURNAL OF MEDICINE

The osteoclast and its unique cytoskeleton

(2011) Steven L. Teitelbaum   Annals of the New York Academy of Sciences

Netrins: versatile extracellular cues with diverse functions

(2011) K. L. W. Sun et al.   DEVELOPMENT

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Transcriptional Regulation of BMP2 Expression by the PTH-CREB Signaling Pathway in Osteoblasts

(2011) Rongrong Zhang et al.   PLoS One

Regulation of bone by the adaptive immune system in arthritis

(2011) Kazuo Okamoto et al.   ARTHRITIS RESEARCH & THERAPY

MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling

(2010) Pilar Gonzalo et al.   DEVELOPMENTAL CELL

Netrin-1 Signaling Dampens Inflammatory Peritonitis

(2010) V. Mirakaj et al.   JOURNAL OF IMMUNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone

(2010) Heng Zhu et al.   Nature Protocols

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein α

(2009) Ellen M. van Beek et al.   FASEB JOURNAL

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

(2009) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression

(2009) A. Paradisi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

(2008) Stanley B. Cohen et al.   ARTHRITIS AND RHEUMATISM

Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis

(2008) Y. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA