Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation

Paracrine tumor signaling induces transdifferentiation of surrounding fibroblasts

(2016) Petr Heneberg   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Microvesicles released from tumor cells disrupt epithelial cell morphology and contractility

(2016) Francois Bordeleau et al.   JOURNAL OF BIOMECHANICS

Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway

(2015) Xiao-Ping Zhao et al.   CANCER LETTERS

Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity

(2015) Alan Serrels et al.   CELL

Extracellular vesicles shuffling intercellular messages: for good or for bad

(2015) Alessandra Lo Cicero et al.   CURRENT OPINION IN CELL BIOLOGY

Small extracellular vesicles as tumor biomarkers for glioblastoma

(2015) Keon Mahmoudi et al.   MOLECULAR ASPECTS OF MEDICINE

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells

(2014) Clint A. Stalnecker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-based discovery of cellular-active allosteric inhibitors of FAK

(2013) Naoki Tomita et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Autocrine-Derived Epidermal Growth Factor Receptor Ligands Contribute to Recruitment of Tumor-Associated Macrophage and Growth of Basal Breast Cancer Cells In Vivo

(2013) Nicole K. Nickerson et al.   ONCOLOGY RESEARCH

Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development

(2013) Yuchen Liu et al.   Protein & Cell

Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

(2012) Dolores Di Vizio et al.   AMERICAN JOURNAL OF PATHOLOGY

Extracellular vesicles - vehicles that spread cancer genes

(2012) Janusz Rak et al.   BIOESSAYS

Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

(2012) Kristy K. Ward et al.   CLINICAL & EXPERIMENTAL METASTASIS

Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis

(2012) Sarah Hopkins et al.   DEVELOPMENTAL CELL

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

(2012) Huilin Shao et al.   NATURE MEDICINE

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

(2011) M. A. Antonyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survivin is released from cancer cells via exosomes

(2010) Salma Khan et al.   APOPTOSIS

The dual kinase complex FAK-Src as a promising therapeutic target in cancer

(2010) Victoria Bolós   OncoTargets and Therapy

Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals

(2009) Xiang H.-F. Zhang et al.   CANCER CELL

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin  1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

(2009) T. Shibue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focal adhesion kinase mediates the interferon-γ-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-κB activation

(2008) Zhen Liu et al.   CELLULAR MICROBIOLOGY

The epidermal growth factor receptor ligands at a glance

(2008) Marlon R. Schneider et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY