标题
Parkin Regulates the Activity of Pyruvate Kinase M2
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 19, Pages 10307-10317
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2016-03-15
DOI
10.1074/jbc.m115.703066
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
- (2015) A. Kumar et al. EMBO JOURNAL
- A Ubl/ubiquitin switch in the activation of Parkin
- (2015) V. Sauve et al. EMBO JOURNAL
- Mechanism of phospho-ubiquitin-induced PARKIN activation
- (2015) Tobias Wauer et al. NATURE
- Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma
- (2013) S. R. P. McDonnell et al. BLOOD
- PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
- (2013) William J. Israelsen et al. CELL
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Protein Tyrosine Phosphatase 1B Regulates Pyruvate Kinase M2 Tyrosine Phosphorylation
- (2013) Ahmed Bettaieb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization
- (2013) Lei Lv et al. MOLECULAR CELL
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
- (2012) Taro Hitosugi et al. CANCER CELL
- Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?
- (2012) Ralph J. DeBerardinis et al. CELL
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Serine is a natural ligand and allosteric activator of pyruvate kinase M2
- (2012) Barbara Chaneton et al. NATURE
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- SAICAR Stimulates Pyruvate Kinase Isoform M2 and Promotes Cancer Cell Survival in Glucose-Limited Conditions
- (2012) K. E. Keller et al. SCIENCE
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
- (2011) Lei Lv et al. MOLECULAR CELL
- UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
- (2011) Dawn M. Wenzel et al. NATURE
- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
- (2011) Jason W Locasale et al. NATURE GENETICS
- Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
- (2011) C. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
- (2011) D. Anastasiou et al. SCIENCE
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
- (2010) M. G. Vander Heiden et al. SCIENCE
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
- (2009) Selvaraju Veeriah et al. NATURE GENETICS
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Histone Ubiquitination: Triggering Gene Activity
- (2008) Vikki M. Weake et al. MOLECULAR CELL
- Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
- (2008) Arno F. Alpi et al. MOLECULAR CELL
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- Negative regulation of the deacetylase SIRT1 by DBC1
- (2008) Wenhui Zhao et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
- (2008) Allyson E. Vaughn et al. NATURE CELL BIOLOGY
- Parkin as a tumor suppressor gene for hepatocellular carcinoma
- (2008) M Fujiwara et al. ONCOGENE
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