Editorial Material
Biology
Jane A. Cauley, Dolores M. Shoback
Summary: More informed discussions between physicians and older adults about the consequences of an initial osteoporotic fracture could lead to more patients considering treatments to prevent future fractures.
Editorial Material
Plant Sciences
Li Song, Weitao Li, Xuewei Chen
Summary: A recent study demonstrates the role of the rice TF APIP5 in immune regulation, expanding our understanding of plant TFs beyond their transcription factor functions.
TRENDS IN PLANT SCIENCE
(2022)
Article
Multidisciplinary Sciences
Zuzana Brokesova, Cary Deck, Jana Peliova
Summary: This study discusses the pull-to-center effect observed in newsvendor experiments and compares it with the behavior in a price gouging game. The results suggest that the previously observed pull-to-center effect is driven by structural aspects of the task rather than context specific explanations related to inventory management.
Article
Multidisciplinary Sciences
Gizem Ceylan, Ian A. Anderson, Wendy Wood
Summary: In this research, it is shown that the structure of online sharing on social platforms is more influential than individual deficits in critical reasoning and partisan bias in driving the sharing of misinformation. The reward-based learning systems on social media lead users to form habits of sharing attention-seeking information, regardless of its accuracy. These habits account for a significant portion of false news sharing and are established by social media platforms. However, it is suggested that social media sites can be restructured to promote the sharing of accurate information.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Yanhui Hu, Ben Ewen-Campen, Aram Comjean, Jonathan Rodiger, Stephanie E. Mohr, Norbert Perrimon
Summary: Paralogs are genes that arise through gene duplication and pose a challenge to functional genetics research when they retain overlapping or redundant function. We have developed Paralog Explorer, an online resource that enables researchers to identify candidate paralogous genes in model organisms' genomes and provides access to relevant databases for gene co-expression, protein-protein and genetic interactions, as well as gene ontology and phenotype annotations. This tool expands the capabilities of current ortholog prediction resources for the identification and study of paralogous genes.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)
Review
Pharmacology & Pharmacy
Xiaoyu Zhu, Lili Jiang, Xuejiao Wei, Mengtuan Long, Yujun Du
Summary: Roxadustat is a newly approved hypoxia-inducible factor prolyl hydroxylase inhibitor that has shown favorable safety and efficacy in treating renal anemia. Studies have also indicated its potential for treating other hypoxia-related diseases. Although no significant adverse or off-target effects have been found in clinical studies of roxadustat, clinicians should remain vigilant about these possibilities.
FRONTIERS IN PHARMACOLOGY
(2022)
Editorial Material
Multidisciplinary Sciences
Melissa Flagg
Summary: Funders should prioritize pragmatism, as the current obsession with novelty runs the risk of rendering science irrelevant.
Editorial Material
Oncology
Payton D. Stevens, Bart O. Williams
Summary: LGR4 is known for its role in regulating cell response to Wnt ligands and EGFR signaling. High levels of Lgr4 expression correlate strongly with EGFR signaling, challenging the understanding of the contributions of Wnt signaling and EGFR signaling in cancer.
Article
Economics
Pilar Poncela, Esther Ruiz, Karen Miranda
Summary: Dynamic factor models, along with Kalman filter and smoothing (KFS) procedures, have been the main big data tools used by empirical macroeconomists over the past 30 years. This paper provides a comprehensive updated summary of the literature on latent common factors extracted using KFS procedures in the context of dynamic factor models, addressing signal extraction, parameter estimation, and identification issues. Empirical applications in both stationary and non-stationary models are also surveyed, making this survey relevant to researchers and practitioners in macroeconomics and finance.
INTERNATIONAL JOURNAL OF FORECASTING
(2021)
Editorial Material
Hematology
Jeremy P. Wood
Summary: Researchers have found a new hemostatic mechanism of rFVIIa, showing that it can generate a procoagulant membrane surface through PS-containing EVs released by endothelial cells. This TF-independent function of rFVIIa contributes to promoting thrombin generation and clot formation.
Article
Mathematics
Victor Beresnevich, Lifan Guan, Antoine Marnat, Felipe Ramirez, Sanju Velani
Summary: The article discusses the set of Dirichlet improvable real numbers in different dimensions. In one dimension, it consists of badly approximable and singular numbers, while in higher dimensions, there exist continuum many Dirichlet improvable vectors that do not fall into these categories. The notion of intermediate Dirichlet improvable sets is introduced and its relationship with approximations by rational planes is proven. This extends a classical theorem and has implications for Diophantine sets.
ADVANCES IN MATHEMATICS
(2022)
Editorial Material
Multidisciplinary Sciences
Andrea E. Berardi
Summary: A false start mutation leads to a decrease in protein and flower color, emphasizing the significance of mutations affecting protein translation in phenotypic evolution and variation.
Editorial Material
Physics, Multidisciplinary
Richard J. C. Brown, Martin J. T. Milton
Summary: The SI prefixes are crucial for effectively communicating scientific information, as explained by Richard Brown and Martin Milton in their update.
Article
Immunology
Julien Paganini, Pierre Pontarotti
Summary: Highly polymorphic loci have evolved multiple times in evolutionary history, playing roles in species recognition, self-incompatibility, and the adaptive immune system. These loci encode proteins that interact homophilically or heterophilically for self or non-self recognition. A proposed mechanism called the capacity of recognition competition may contribute to the evolution of MHC polymorphism.
FRONTIERS IN IMMUNOLOGY
(2021)
Editorial Material
Multidisciplinary Sciences
Brita Kilburg-Basnyat
Summary: The student stated that they don't think industry is a good fit because they are not motivated by money. As an industry scientist, this surprised me. I was attending a conference event to help graduate students and postdocs explore career options and connect with professionals from various fields. Most attendees were eager to learn about their options and some were seriously considering industry. I was glad to assist them in figuring out if it was the right path for them and how to get there. The dismissive comment from the student caught me off-guard, however, I suspect others may have felt the same way. After a brief pause, I shared my own journey.
