期刊
CANCER LETTERS
卷 356, 期 2, 页码 273-280出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2014.02.026
关键词
Colorectal cancer; Diet; Microbiota; Butyrate; Mitochondria; Energy metabolism
类别
资金
- Folke Hermansen Cancer Fund
- Institute of Surgical Sciences
- Mjaaland Cancer Fund
The interconnectivity between diet, gut microbiota and cell molecular responses is well known; however, only recently has technology allowed the identification of strains of microorganisms harbored in the gastrointestinal tract that may increase susceptibility to cancer. The colonic environment appears to play a role in the development of colon cancer, which is influenced by the human metabolic lifestyle and changes in the gut microbiome. Studying metabolic changes at the cellular level in cancer be useful for developing novel improved preventative measures, such as screening through metabolic breath-tests or treatment options that directly affect the metabolic pathways responsible for the carcinogenicity. (C) 2014 The Authors. Published by Elsevier Ireland Ltd.
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