Antineoplastic copper coordinated complexes (Casiopeinas) uncouple oxidative phosphorylation and induce mitochondrial permeability transition in cardiac mitochondria and cardiomyocytes

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

(2013) Vernon W. Dolinsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Extensive evaluations of the cytotoxic effects of gold nanoparticles

(2013) Show-Mei Chuang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin

(2013) Zbynek Heger et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Imaging of reactive oxygen species burst from mitochondria using laser scanning confocal microscopy

(2013) Jingman Xu et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Whole Genome Gene Expression Analysis Reveals Casiopeína-Induced Apoptosis Pathways

(2013) Alejandra Idan Valencia-Cruz et al.   PLoS One

Cardiac Toxicity of Anticancer Agents

(2013) Alessandro Colombo et al.   Current Cardiology Reports

Casiopeina II-gly and bromo-pyruvate inhibition of tumor hexokinase, glycolysis, and oxidative phosphorylation

(2012) Alvaro Marín-Hernández et al.   ARCHIVES OF TOXICOLOGY

Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation

(2012) Cristina Trejo-Solís et al.   BMC CANCER

Pharmacokinetics and hematotoxicity of a novel copper-based anticancer agent: Casiopeina III-Ea, after a single intravenous dose in rats

(2012) Guadalupe Vértiz et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Cardiotoxicity of acetogenins from Persea americana occurs through the mitochondrial permeability transition pore and caspase-dependent apoptosis pathways

(2012) Christian Silva-Platas et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

New achievements on biological aspects of copper complexes Casiopeínas®: Interaction with DNA and proteins and anti-Trypanosoma cruzi activity

(2012) Lorena Becco et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genotoxicity of the copper antineoplastic coordination complexes casiopeinas®

(2011) J. Serment-Guerrero et al.   TOXICOLOGY IN VITRO

Comparison between the antiproliferative effect and intracellular glutathione depletion induced by Casiopeína IIgly and cisplatin in murine melanoma B16 cells

(2011) Radamés Alemón-Medina et al.   TOXICOLOGY IN VITRO

Inhibition of glycogen synthase kinase 3β prevents peroxide-induced collapse of mitochondrial membrane potential in rat ventricular myocytes

(2010) Karina Förster et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Casiopeinas IIgly and IIIia Induce Apoptosis in Medulloblastoma Cells

(2009) Carmen Mejia et al.   PATHOLOGY & ONCOLOGY RESEARCH

Casiopeína IIgly-induced oxidative stress and mitochondrial dysfunction in human lung cancer A549 and H157 cells

(2009) Remy Kachadourian et al.   TOXICOLOGY

The Effect of N-Ethylmaleimide on Permeability Transition as Induced by Carboxyatractyloside, Agaric Acid, and Oleate

(2008) Noemí García et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity

(2008) Yolanda I. Chirino et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Antiproliferative activity and QSAR study of copper(II) mixed chelate [Cu(N–N)(acetylacetonato)]NO3 and [Cu(N–N)(glycinato)]NO3 complexes, (Casiopeínas®)

(2008) María Elena Bravo-Gómez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Casiopeína IIgly induced cytotoxicity to HeLa cells depletes the levels of reduced glutathione and is prevented by dimethyl sulfoxide

(2007) Radamés Alemón-Medina et al.   TOXICOLOGY IN VITRO