Article
Chemistry, Multidisciplinary
Xiao He, Zhangkang Li, Jia Li, Dinesh Mishra, Yuxuan Ren, Ian Gates, Jinguang Hu, Qingye Lu
Summary: An ultrastretchable hydrogel with strong antibacterial activity has been developed for manufacturing robust micro/nanofibers, showing promising mechanical properties suitable for applications such as nets and safety cords. Additionally, nanosized hydrogel fibers spun on personal protective equipment exhibit near 100% killing efficiency against airborne bacteria aerosols, indicating their potential in disinfection-related applications.
Review
Polymer Science
Jie Cai, Jiaming Guo, Shige Wang
Summary: Postoperative adhesion is a common complication after surgery, involving the formation of fibrous bridges between different layers of tissues. Despite progress in understanding the mechanism, effective prevention of adhesion is still challenging. Hydrogels, as water-expanding polymers with drug-loading capability, have shown promising antifouling abilities for preventing postoperative adhesion. This review summarizes the current research status of hydrogels as anti-adhesion barriers, highlights their characteristics in preventing adhesion, and discusses future research directions.
Article
Materials Science, Multidisciplinary
Susu Huang, Yuelin Fang, Boguang Yang, Prabhleen Kaur, Yanqing Wang, Jicheng Zhang, Qiaoying Hu, Xiaoye Yang, Yabin Zhang, Guangxi Zhai, Lei Ye
Summary: Postoperative adhesions are a common complication after intraperitoneal surgery, with a high recurrence rate. A series of poly(sulfobetaine methacrylate) grafted dextran derivatives were synthesized, which can self-assemble into a physical hydrogel under physiological conditions, effectively preventing postoperative adhesions.
MATERIALS & DESIGN
(2023)
Article
Chemistry, Applied
Huichang Gao, Chenxi Yu, Qingtao Li, Xiaodong Cao
Summary: A novel injectable DMEM-induced phenylboronic acid-modified hyaluronic acid self-crosslinking hydrogel was designed in this study, which exhibited good self-healing properties and tissue adhesion. It is capable of supporting cell loading and proliferation, making it a promising candidate for tissue repair materials.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Pengfei Ren, Liuxin Yang, Dandan Wei, Min Liang, Li Xu, Tianzhu Zhang, Wanjun Hu, Zhigang Zhang, Qianli Zhang
Summary: In this study, a supramolecular hydrogel system with improved adhesion was constructed through host-guest interactions between alginate and polyacrylamide. The hydrogel exhibited high tensile adhesion strength and demonstrated excellent self-healing, shear-thinning, and injectable properties. It can serve as a viscosity extender or bioadhesive, and as a carrier material for minimally invasive injection.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Atefeh Afroozan Bazghaleh, Mojtaba Akbari Dogolsar, Jalal Barzin
Summary: In this study, biocompatible composite hydrogels were prepared using water-soluble chitosan and oxidized pectin without a chemical crosslinking agent. The hydrogels exhibited fast gelation time, excellent swelling ability, good hemocompatibility, well biological compatibility, and sufficient antibacterial activity. The findings suggest that these composite hydrogels have great potential for biomedical applications.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Polymer Science
Cristina Vercelli, Giovanni Re, Selina Iussich, Rosangela Odore, Emanuela Maria Morello, Marco Gandini, Gessica Giusto
Summary: This study compared plain polypropylene mesh with a pectin-honey hydrogel-coated polypropylene mesh in an acute hernia model in rats. The coated mesh did not reduce adhesion formation compared to uncoated mesh, but it did improve peritoneal regeneration and tissue healing.
Article
Materials Science, Multidisciplinary
Nolan Wen, Enze Qian, Yunqing Kang
Summary: This study aims to develop and characterize a new hydrogel system with tunable stretchability and adhesive properties. The hydrogel was prepared using a one-pot method, crosslinked with acrylamide, natural plant derived materials (pectin and tannic acid), ammonium persulfate, N, N'-methylenebisacrylamide, and iron chloride, with or without tetramethylethylenediamine. Incorporating laponite powders significantly improved the compressive strength and stability of the hydrogel but reduced its stretchability. The newly developed hydrogel formulations demonstrate tunable mechanical properties and good adhesion, showing great potentials in various biomedical applications.
Article
Engineering, Biomedical
Ramu Janarthanan, Rangasamy Jayakumar, Subramania Iyer
Summary: This study aimed to improve the efficiency of autologous fat grafting (AFG) by using a hydrogel as a carrier and adding platelet-rich plasma (PRP). The results showed that the hydrogel and PRP group had enhanced cell viability and proliferation, as well as improved angiogenesis and adipogenesis compared to the control group. Thus, the hydrogel-based fat graft system with PRP can optimize the clinical outcomes of AFG.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Agricultural Engineering
Yanxia Chao, Huichang Gao, Xiang Zhu, Huibin Wang, Zhuohong Yang, Wuyi Zhou, Yaozong Li, Huangwei Chen, Yu Yang, Yang Hu
Summary: This study reports a tannic acid-coated cellulose nanocrystals/pectin/polyacrylic acid nanocomposite hydrogel (TPP hydrogel). The TPP hydrogel exhibits favorable mechanical strength, adhesion performance, anti-swelling behavior, antibacterial activity, and biocompatibility, with high stretchability, excellent elasticity, and fatigue resistance.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Polymer Science
Chao Guo, Junqiang Qi, Jia Liu, Haotian Wang, Yifei Liu, Yingying Feng, Guohua Xu
Summary: This study developed a novel calcium silicate bone cement by compounding polylactic acid-polyethylene glycol-polylactic acid hydrogel with tricalcium silicate/dicalcium silicate/plaster of Paris. The physical and chemical properties, as well as the cell compatibility and osteogenic capability, of the cement were tested. In vivo experiments using a rabbit model confirmed the safety and effectiveness of the cement in bone repair. The findings suggest that the PLGA-PEG-PLGA/C3S/C2S/POP composite bone cement has potential for clinical application in bone tissue engineering.
Article
Biochemistry & Molecular Biology
Yanai Chen, Yu Zhang, Limin Chang, Weichen Sun, Wenhao Duan, Jianglei Qin
Summary: A biodegradable self-healing hydrogel with mussel inspired bioadhesion and anti-oxidation properties was fabricated for diabetic wound repair dressing. The hydrogel, made from dopamine coupled pectin hydrazide (Pec-DH) and oxidized carboxymethyl cellulose (DCMC), exhibited fast formation and good sealing effect on irregular wounds. The catechol structure in the hydrogel enhanced tissue adhesion and ROS scavenging ability. In vivo experiments showed that the hydrogel loaded with mEGF greatly improved the diabetic wound repairing rate in a mouse model, making it a promising EGF carrier in wound healing applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Gi Doo Cha, Wang Hee Lee, Sung-Hyuk Sunwoo, Dayoung Kang, Taegyu Kang, Kyoung Won Cho, Minjeong Kim, Ok Kyu Park, Dongjun Jung, Jongha Lee, Seung Hong Choi, Taeghwan Hyeon, Dae-Hyeong Kim
Summary: The study proposes a material design strategy for a multifunctional injectable hydrogel with good adhesiveness, stretchability, and bioresorbability. The hydrogel can be administered through minimally invasive procedure, form a conformal adhesive interface with target tissue, and be resorbed in vivo after a certain period. The incorporation of functional nanomaterials allows for various in vivo diagnostic and therapeutic applications without compromising the original multifunctionality of the hydrogel.
Review
Polymer Science
Bapan Pramanik
Summary: Thixotropy, a fascinating property of gel systems, has attracted significant attention in the medical field. This review focuses on the rational design and self-assembly of peptide-based thixotropic hydrogels, along with their biomedical applications in drug delivery and tissue regeneration.
Article
Engineering, Biomedical
Shanshan Xu, Chenhong Wang, Ruoqing Mao, Xiaoyu Liang, Heran Wang, Zhenyu Lin, Jiangxue Li, Shilin Li, Jipeng Jiang, Tongshuo Zhang, Yongfu Ma, Yang Liu, Charles C. Han, Ying Liu
Summary: A fibrous membrane with an ECM-like structure was shown to significantly reduce peritoneal adhesion, with less inflammatory response and better effectiveness compared to other smooth surface films. Studies in animal models and a small clinical trial supported its potential as a favorable implant for preventing postoperative adhesion.
BIOACTIVE MATERIALS
(2022)
Article
Biology
Mikhail F. Borisenkov, Sergey Popov, Vasily V. Smirnov, Denis G. Gubin, Ivan M. Petrov, Tatyana N. Vasilkova, Svetlana Solovieva, Ekaterina A. Martinson, Anna A. Pecherkina, Olga Dorogina, Elvira E. Symaniuk
Summary: This study aims to evaluate the associations between time perspective, sleep-wake rhythm characteristics, and psycho-emotional state during COVID-19 isolation. The results indicate that individuals with positive time perspective towards the future and past have better sleep characteristics and are less likely to exhibit symptoms of depression.
BIOLOGICAL RHYTHM RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
Daria S. Khramova, Sergey V. Popov
Summary: Saliva plays a multifunctional role in the oral cavity, with its importance in oral health and food perception becoming increasingly recognized. The variability in saliva composition and secretion contributes to the individualized experience of food perception.
EUROPEAN JOURNAL OF ORAL SCIENCES
(2022)
Article
Chemistry, Medicinal
Sergey Popov, Nikita Paderin, Daria Khramova, Elizaveta Kvashninova, Anatoliy Melekhin, Fedor Vityazev
Summary: This study aimed to investigate the influence of kappa-carrageenan on the initial stages of the foreign body response against pectin gel. The inclusion of kappa-carrageenan in the apple pectin gel was found to improve its biocompatibility.
Article
Nutrition & Dietetics
Isabel Baenas, Mikel Etxandi, Lucero Munguia, Roser Granero, Gemma Mestre-Bach, Isabel Sanchez, Emilio Ortega, Alba Andreu, Violeta L. Moize, Jose-Manuel Fernandez-Real, Francisco J. Tinahones, Carlos Dieguez, Gema Fruhbeck, Daniel Le Grange, Kate Tchanturia, Andreas Karwautz, Michael Zeiler, Hartmut Imgart, Annika Zanko, Angela Favaro, Laurence Claes, Ia Shekriladze, Eduardo Serrano-Troncoso, Raquel Cecilia-Costa, Teresa Rangil, Maria Eulalia Loran-Meler, Jose Soriano-Pacheco, Mar Carceller-Sindreu, Rosa Navarrete, Meritxell Lozano, Raquel Linares, Carlota Gudiol, Jordi Carratala, Maria T. Plana, Montserrat Graell, David Gonzalez-Parra, Jose A. Gomez-del Barrio, Ana R. Sepulveda, Jessica Sanchez-Gonzalez, Paulo P. P. Machado, Anders Hakansson, Ferenc Tury, Bea Paszthy, Daniel Stein, Hana Papezova, Jana Gricova, Brigita Bax, Mikhail F. Borisenkov, Sergey V. Popov, Denis G. Gubin, Ivan M. Petrov, Dilara Isakova, Svetlana V. Mustafina, Youl-Ri Kim, Michiko Nakazato, Nathalie Godart, Robert van Voren, Tetiana Ilnytska, Jue Chen, Katie Rowlands, Ulrich Voderholzer, Alessio M. Monteleone, Janet Treasure, Susana Jimenez-Murcia, Fernando Fernandez-Aranda
Summary: The COVID-19 lockdown has significantly impacted patients with eating disorders (ED), with binge eating disorder (BED) patients experiencing the highest impact on weight and ED symptoms. Other specified feeding and eating disorders (OFSED) patients showed greater deterioration in general psychological functioning. Asian and younger individuals appeared to be more resilient.
Article
Biochemistry & Molecular Biology
Sergey Popov, Nikita Paderin, Daria Khramova, Elizaveta Kvashninova, Olga Patova, Fedor Vityazev
Summary: The study aimed to develop gel beads with improved functional properties and biocompatibility from hogweed (HS) pectin. The HS4 gel beads showed higher swelling degree, lower hardness, lower serum protein adsorption, lower hemolysis, and complement activation compared to the apple pectin (AP) gel beads (AP4). Additionally, HS4 gel beads exhibited an inhibitory effect on the inflammatory response of macrophages, while AP4 gel beads stimulated the inflammatory response.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Sergey Popov, Nikita Paderin, Elizaveta Chistiakova, Dmitry Ptashkin
Summary: The adhesion of cross-linked low-methyl esterified pectin hydrogel to rat intestinal serosa was investigated. FeP hydrogel showed higher adhesion than hydrogels cross-linked by Ca2+, Zn2+, and Al3+ cations. The concentration of cross-linking cation did not affect the adhesion of the pectin hydrogel. The mechanical properties and surface microrelief of the hydrogel were influenced by the type and concentration of the cross-linking cations. FeP hydrogel demonstrated better stability and mechanical properties in physiological environments, making it a promising bioadhesive for tissue engineering.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Elena Gunter, Oxana Popeyko, Sergey Popov
Summary: The aim of this study was to obtain alginate hydrogels with immobilized callus cells to investigate the interaction between physicochemical properties, texture, swelling behavior, and grape seed extract (GSE) release. The inclusion of duckweed and campion callus cells in hydrogels resulted in a decrease in porosity, gel strength, adhesiveness, and thermal stability, and an increase in encapsulation efficiency compared with alginate hydrogel.
Article
Chemistry, Medicinal
Sergey Popov, Nikita Paderin, Elizaveta Chistiakova, Dmitry Ptashkin, Fedor Vityazev, Pavel A. Markov, Kirill S. Erokhin
Summary: Chitosan was incorporated into pectin ionotropic gel to enhance its mechanical and bioadhesive properties. Different chitosan weight fractions were used to prepare the pectin-chitosan gels, which were characterized by rheological tests, penetration tests, and serosal adhesion ex vivo assays. The results showed that the addition of chitosan improved the mechanical stability and adhesivity of the pectin gel, with the highest values observed in P-Ch1 gel.
Article
Nutrition & Dietetics
Mikhail F. Borisenkov, Sergey V. Popov, Vasily V. Smirnov, Ekaterina A. Martinson, Svetlana V. Solovieva, Lina A. Danilova, Denis G. Gubin
Summary: This study investigates the association between the consumption of foods containing melatonin (MT) and circadian rhythm in adolescents and young adults. The findings suggest that the intake of MT-rich foods is related to chronotype, social jetlag, sleep quality, depression levels, and central adiposity.
Article
Nutrition & Dietetics
Mikhail F. Borisenkov, Tatyana A. Tserne, Sergey V. Popov, Vasily V. Smirnov, Olga I. Dorogina, Anna A. Pecherkina, Elvira E. Symaniuk
Summary: Adolescents are at risk for circadian misalignment, which can lead to negative effects on their psychological, emotional, cognitive, and weight disorders. This study found that circadian eating disorders are more common in adolescents with poor academic performance, high levels of depression, and food addiction.
Article
Polymer Science
Kseniya Belova, Elena Dushina, Sergey Popov, Andrey Zlobin, Ekaterina Martinson, Fedor Vityazev, Sergey Litvinets
Summary: The study aims to develop and evaluate the printability of k-carrageenan inks enriched with lupin callus tissue and examine their effect on the texture and digestibility of 3D-printed gel. Results showed successful 3D printing of enriched ink at specific concentrations of callus. Higher concentrations of callus material reduced the feasibility of 3D printing. The texture and rheological properties of the gel were influenced by the type and concentration of callus used. Incorporating lupin callus into hydrocolloid ink for food 3D printing could lead to the development of gelling material with new properties.
Article
Ecology
S. G. Litvinets, E. A. Martinson, S. M. Kuznetsov, E. O. Zadorina, O. A. Novikova, V. G. Komosko, A. Nikolaeva, M. A. Troshin, M. T. Gaysin
Summary: The effectiveness of the Dimex solid dispersant for cleaning the water surface from films of oil and oil products through dispersion, including in winter conditions, has been studied. The results showed that the Dimex solid dispersant is highly efficient under various conditions.
THEORETICAL AND APPLIED ECOLOGY
(2022)
Article
Psychiatry
Mikhail F. Borisenkov, Sergey Popov, Vasily V. Smirnov, Denis G. Gubin, Ivan M. Petrov, Tatyana N. Vasilkova, Svetlana Solovieva, Ekaterina A. Martinson, Anna A. Pecherkina, Olga Dorogina, Elvira E. Symaniuk
Summary: The incidence rate of food addiction increased during COVID-19 isolation, and individuals with present time perspective were more likely to exhibit signs of food addiction.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
