ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3

On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain

(2021) Wei-Siang Liau et al.   RNA Biology

In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish

(2021) Zherui Xiong et al.   eLife

The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum

(2021) Fei Wang et al.   CELL DEATH AND DIFFERENTIATION

Activity-regulated synaptic targeting of lncRNA ADEPTR mediates structural plasticity by localizing Sptn1 and AnkB in dendrites

(2021) Eddie Grinman et al.   Science Advances

A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb

(2020) Mei Ma et al.   CELL RESEARCH

Regulation of impulsive and aggressive behaviours by a novel lncRNA

(2020) Benoit Labonté et al.   MOLECULAR PSYCHIATRY

Role of long non-coding RNA Gas5 in cocaine action

(2020) Haiyang Xu et al.   BIOLOGICAL PSYCHIATRY

Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction

(2020) Paul R. Marshall et al.   NATURE NEUROSCIENCE

Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression

(2020) Orna Issler et al.   NEURON

Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking

(2020) Ashley E. Lepack et al.   SCIENCE

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice

(2020) Michail S. Kukharsky et al.   Translational Psychiatry

Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems

(2020) Nancy V N Carullo et al.   NUCLEIC ACIDS RESEARCH

Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes

(2019) Liang-Fu Chen et al.   Cell Reports

The DNA modification N6-methyl-2’-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction

(2019) Xiang Li et al.   NATURE NEUROSCIENCE

Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment

(2019) Anderson A. Butler et al.   Science Signaling

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

(2019) Yongchuan Zhu et al.   Nature Communications

Pharmacological activation of Nr4a rescues age-associated memory decline

(2019) Snehajyoti Chatterjee et al.   NEUROBIOLOGY OF AGING

Down-regulation of Long Noncoding RNA MALAT1 Protects Hippocampal Neurons Against Excessive Autophagy and Apoptosis via the PI3K/Akt Signaling Pathway in Rats with Epilepsy

(2018) Qiang Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

(2018) Tomohiro Yamazaki et al.   MOLECULAR CELL

SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates

(2018) Raghuvaran Shanmugam et al.   NUCLEIC ACIDS RESEARCH

Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

(2018) Dingfeng Li et al.   Nature Communications

14-3-3 Proteins in Glutamatergic Synapses

(2018) Jiajing Zhang et al.   NEURAL PLASTICITY

Universal Alternative Splicing of Noncoding Exons

(2018) Ira W. Deveson et al.   Cell Systems

The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain

(2018) Ivelisse Cajigas et al.   MOLECULAR CELL

Regulation of Neuroregeneration by Long Noncoding RNAs

(2018) Rotem Ben-Tov Perry et al.   MOLECULAR CELL

GADD45A binds R-loops and recruits TET1 to CpG island promoters

(2018) Khelifa Arab et al.   NATURE GENETICS

Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function

(2018) Bindu L. Raveendra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroepigenetic mechanisms underlying fear extinction: emerging concepts

(2018) Paul R. Marshall et al.   PSYCHOPHARMACOLOGY

Altered Levels of Long NcRNAs Meg3 and Neat1 in Cell And Animal Models Of Huntington’s Disease

(2018) Kaushik Chanda et al.   RNA Biology

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance

(2017) Jana Seiler et al.   NUCLEIC ACIDS RESEARCH

N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

(2017) Nian Liu et al.   NUCLEIC ACIDS RESEARCH

eRNA binding produces tailored CBP activity profiles to regulate gene expression

(2017) Daniel A. Bose et al.   RNA Biology

The Dimensions, Dynamics, and Relevance of the Mammalian Noncoding Transcriptome

(2017) Ira W. Deveson et al.   TRENDS IN GENETICS

DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression

(2016) Cristiana Cruceanu et al.   BMC Psychiatry

Improved definition of the mouse transcriptome via targeted RNA sequencing

(2016) Giovanni Bussotti et al.   GENOME RESEARCH

Regulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation

(2016) Sara C. Cloutier et al.   MOLECULAR CELL

Sex differences in learned fear expression and extinction involve altered gamma oscillations in medial prefrontal cortex

(2016) Georgina E. Fenton et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Pharmacological Activators of the NR4A Nuclear Receptors Enhance LTP in a CREB/CBP-Dependent Manner

(2016) Morgan S Bridi et al.   NEUROPSYCHOPHARMACOLOGY

Inhibition of 14-3-3 Proteins Leads to Schizophrenia-Related Behavioral Phenotypes and Synaptic Defects in Mice

(2015) Molly Foote et al.   BIOLOGICAL PSYCHIATRY

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

(2015) Paola A. Spadaro et al.   BIOLOGICAL PSYCHIATRY

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

MAP1B and NOS1 genes are associated with working memory in youths with attention-deficit/hyperactivity disorder

(2015) Angélica Salatino-Oliveira et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

DNA methylation changes in plasticity genes accompany the formation and maintenance of memory

(2015) Rashi Halder et al.   NATURE NEUROSCIENCE

Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

(2015) Jian Feng et al.   NATURE NEUROSCIENCE

Enhancer RNAs: A Class of Long Noncoding RNAs Synthesized at Enhancers: Figure 1.

(2015) Tae-Kyung Kim et al.   Cold Spring Harbor Perspectives in Biology

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

(2015) Monica D. Bjørge et al.   Cell Reports

Increased Expression of the PI3K Enhancer PIKE Mediates Deficits in Synaptic Plasticity and Behavior in Fragile X Syndrome

(2015) Christina Gross et al.   Cell Reports

Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution

(2015) Moran N Cabili et al.   GENOME BIOLOGY

Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories

(2014) Johannes Gräff et al.   CELL

14-3-3 Proteins Are Required for Hippocampal Long-Term Potentiation and Associative Learning and Memory

(2014) H. Qiao et al.   JOURNAL OF NEUROSCIENCE

Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females

(2014) G. E. Fenton et al.   LEARNING & MEMORY

Enhancer RNA Facilitates NELF Release from Immediate Early Genes

(2014) Katie Schaukowitch et al.   MOLECULAR CELL

Genome-wide identification and characterization of functional neuronal activity–dependent enhancers

(2014) Athar N Malik et al.   NATURE NEUROSCIENCE

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

(2014) Tim R Mercer et al.   Nature Protocols

Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation

(2014) X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation

(2013) Mark A. Marzinke et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Activation of BDNF signaling prevents the return of fear in female mice

(2013) D. Baker-Andresen et al.   LEARNING & MEMORY

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing

(2013) G Barry et al.   MOLECULAR PSYCHIATRY

Structure and function of long noncoding RNAs in epigenetic regulation

(2013) Tim R Mercer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

(2012) Richard Sando et al.   CELL

p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear

(2012) W. Wei et al.   JOURNAL OF NEUROSCIENCE

Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory

(2012) S. E. McNulty et al.   LEARNING & MEMORY

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

(2012) Claudia Carrieri et al.   NATURE

Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders

(2012) Paola A. Spadaro et al.   Frontiers in Genetics

YY1 Tethers Xist RNA to the Inactive X Nucleation Center

(2011) Yesu Jeon et al.   CELL

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

(2011) Tim R Mercer et al.   NATURE BIOTECHNOLOGY

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

(2011) Quan Lin et al.   NATURE NEUROSCIENCE

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

ChIP-based methods for the identification of long-range chromatin interactions

(2009) Melissa J. Fullwood et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Nonlinear Fitting Method for Determining Local False Discovery Rates from Decoy Database Searches

(2008) Wilfred H. Tang et al.   JOURNAL OF PROTEOME RESEARCH

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY