β-Amyloid in blood neuronal-derived extracellular vesicles is elevated in cognitively normal adults at risk of Alzheimer’s disease and predicts cerebral amyloidosis

Plasma β-Amyloid Levels Associated With Structural Integrity Based on Diffusion Tensor Imaging in Subjective Cognitive Decline: The SILCODE Study

(2021) Xiaoni Wang et al.   Frontiers in Aging Neuroscience

Entorhinal Perfusion Predicts Future Memory Decline, Neurodegeneration, and White Matter Hyperintensity Progression in Older Adults

(2021) Katherine J. Bangen et al.   JOURNAL OF ALZHEIMERS DISEASE

Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer Disease

(2021) Danielle V. Mayblyum et al.   NEUROLOGY

Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

(2021) Elisabeth H. Thijssen et al.   Scientific Reports

Glucose metabolism in the right middle temporal gyrus could be a potential biomarker for subjective cognitive decline: a study of a Han population

(2021) Qiu-Yue Dong et al.   Alzheimers Research & Therapy

Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease

(2021) Francheska Delgado-Peraza et al.   Cells

Biomarkers and Tools for Predicting Alzheimer’s Disease at the Preclinical Stage

(2021) Tao-Ran Li et al.   Current Neuropharmacology

Women Exhibit Lower Global Left Frontal Cortex Connectivity Among Cognitively Unimpaired Elderly Individuals: A Pilot Study from SILCODE

(2021) Wenying Du et al.   JOURNAL OF ALZHEIMERS DISEASE

“Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies

(2021) Yuxing Xia et al.   Molecular Neurodegeneration

Blood biomarkers for the diagnosis of amnestic mild cognitive impairment and Alzheimer’s disease: A systematic review and meta-analysis

(2021) Yi Qu et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Proteome profiling of neuron-derived exosomes in Alzheimer's disease reveals hemoglobin as a potential biomarker

(2021) Burak Ibrahim Arioz et al.   NEUROSCIENCE LETTERS

Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease

(2021) Shorena Janelidze et al.   JAMA Neurology

Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles

(2021) Marzia Perluigi et al.   Alzheimers & Dementia

Exploring brain glucose metabolic patterns in cognitively normal adults at risk of Alzheimer’s disease: A cross-validation study with Chinese and ADNI cohorts

(2021) Tao-Ran Li et al.   NeuroImage-Clinical

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

(2020) Thomas K Karikari et al.   LANCET NEUROLOGY

CSF biomarkers in Olmsted County

(2020) Argonde C. Van Harten et al.   NEUROLOGY

Assessment of Alzheimer’s Disease Based on Texture Analysis of the Entorhinal Cortex

(2020) Stephanos Leandrou et al.   Frontiers in Aging Neuroscience

Increased prediction value of biomarker combinations for the conversion of mild cognitive impairment to Alzheimer’s dementia

(2020) Aonan Zhao et al.   Translational Neurodegeneration

Sequence of Alzheimer disease biomarker changes in cognitively normal adults

(2020) Jingqin Luo et al.   NEUROLOGY

Regional Tau Effects on Prospective Cognitive Change in Cognitively Normal Older Adults

(2020) Xi Chen et al.   JOURNAL OF NEUROSCIENCE

Radiomics Analysis of Magnetic Resonance Imaging Facilitates the Identification of Preclinical Alzheimer’s Disease: An Exploratory Study

(2020) Tao-Ran Li et al.   Frontiers in Cell and Developmental Biology

Optimisation and usefulness of quantitative analysis of 18F-florbetapir PET

(2019) Daniel Fakhry-Darian et al.   BRITISH JOURNAL OF RADIOLOGY

Sino Longitudinal Study on Cognitive Decline (SILCODE): protocol for a Chinese longitudinal observational study to develop risk prediction models of conversion to mild cognitive impairment in individuals with subjective cognitive decline

(2019) Xuanyu Li et al.   BMJ Open

Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging

(2019) Dimitrios Kapogiannis et al.   JAMA Neurology

Concordance between the assessment of Aβ42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid

(2019) Longfei Jia et al.   Alzheimers & Dementia

The “rights” of precision drug development for Alzheimer’s disease

(2019) Jeffrey Cummings et al.   Alzheimers Research & Therapy

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Ultrasensitive Detection of Plasma Amyloid-β as a Biomarker for Cognitively Normal Elderly Individuals at Risk of Alzheimer’s Disease

(2019) Pratishtha Chatterjee et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive trajectory in mild cognitive impairment due to primary age-related tauopathy

(2019) Merilee Teylan et al.   BRAIN

Amyloid-β as a Blood Biomarker for Alzheimer’s Disease: A Review of Recent Literature

(2019) Xiaoni Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Extracellular vesicles as an emerging tool for the early detection of Alzheimer’s disease

(2019) Tao-Ran Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Objective subtle cognitive difficulties predict future amyloid accumulation and neurodegeneration

(2019) Kelsey R. Thomas et al.   NEUROLOGY

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years

(2018) Marilyn Albert et al.   BRAIN

Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer’s disease

(2018) Edward J. Goetzl et al.   FASEB JOURNAL

Neuropsychological Criteria for Mild Cognitive Impairment Improves Diagnostic Precision, Biomarker Associations, and Progression Rates

(2018) Mark W. Bondi et al.   JOURNAL OF ALZHEIMERS DISEASE

Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease

(2018) Andrew J. Aschenbrenner et al.   NEUROLOGY

A vaccine against Alzheimer`s disease: anything left but faith?

(2018) Martin F. Bachmann et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes

(2017) Maja Mustapic et al.   Frontiers in Neuroscience

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease

(2016) Min Shi et al.   Alzheimers & Dementia

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer’s disease

(2015) Dimitrios Kapogiannis et al.   FASEB JOURNAL

Cognitive and Brain Profiles Associated with Current Neuroimaging Biomarkers of Preclinical Alzheimer's Disease

(2015) F. L. Besson et al.   JOURNAL OF NEUROSCIENCE

Cell-derived vesicles for drug therapy and diagnostics: Opportunities and challenges

(2015) Gregor Fuhrmann et al.   Nano Today

Association of plasma β-amyloid with MRI markers of structural brain aging the 3-City Dijon study

(2015) Sara Kaffashian et al.   NEUROBIOLOGY OF AGING

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia