Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
出版年份 2022 全文链接
标题
Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
作者
关键词
-
出版物
Nature Communications
Volume 13, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-05-19
DOI
10.1038/s41467-022-30236-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A High-Density Human Mitochondrial Proximity Interaction Network
- (2020) Hana Antonicka et al. Cell Metabolism
- Characterization of MCU-Binding Proteins MCUR1 and CCDC90B — Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles
- (2019) Jyoti Adlakha et al. STRUCTURE
- Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve
- (2019) Tariq R. Altamimi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter
- (2019) Yan Wang et al. CELL
- Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
- (2019) Roberta Tufi et al. Cell Reports
- Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis
- (2019) Alicia J. Kowaltowski et al. FASEB JOURNAL
- Complex I and II are required for normal mitochondrial Ca2+ homeostasis
- (2019) Fabian Jaña et al. MITOCHONDRION
- Quantification of light-induced miniSOG superoxide production using the selective marker, 2-hydroxyethidium
- (2018) Miriam E. Barnett et al. FREE RADICAL BIOLOGY AND MEDICINE
- CellProfiler 3.0: Next-generation image processing for biology
- (2018) Claire McQuin et al. PLOS BIOLOGY
- Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
- (2018) Rozbeh Baradaran et al. NATURE
- Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart
- (2018) Junco S. Warren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium
- (2017) Salah Sommakia et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
- (2017) Zhiwei Dong et al. MOLECULAR CELL
- SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
- (2017) Xin Gu et al. SCIENCE
- Regulation of Mitochondrial Complex I Biogenesis in Drosophila Flight Muscles
- (2017) Christian Joel Garcia et al. Cell Reports
- Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
- (2017) Inge Kühl et al. eLife
- High-throughput Analysis of Locomotor Behavior in the Drosophila Island Assay
- (2017) Ilse Eidhof et al. Jove-Journal of Visualized Experiments
- Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation
- (2017) Donghui Zhang et al. CIRCULATION RESEARCH
- Mitochondrial complex I-linked disease
- (2016) Richard J. Rodenburg BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The architecture of respiratory supercomplexes
- (2016) James A. Letts et al. NATURE
- Architecture of the mitochondrial calcium uniporter
- (2016) Kirill Oxenoid et al. NATURE
- Structure of mammalian respiratory complex I
- (2016) Jiapeng Zhu et al. NATURE
- Atomic structure of the entire mammalian mitochondrial complex I
- (2016) Karol Fiedorczuk et al. NATURE
- Accessory subunits are integral for assembly and function of human mitochondrial complex I
- (2016) David A. Stroud et al. NATURE
- Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio
- (2016) D. V. Titov et al. SCIENCE
- A Guide to Fluorescent Protein FRET Pairs
- (2016) Bryce Bajar et al. SENSORS
- Structural Insights into the Allosteric Operation of the Lon AAA+ Protease
- (2016) Chien-Chu Lin et al. STRUCTURE
- A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria
- (2016) Kenneth Robert Pryde et al. Cell Reports
- Uncovering Aberrant Mutant PKA Function with Flow Cytometric FRET
- (2016) Shin-Rong Lee et al. Cell Reports
- Inhibiting the Mitochondrial Calcium Uniporter during Development Impairs Memory in Adult Drosophila
- (2016) Ilaria Drago et al. Cell Reports
- Impaired Cellular Bioenergetics Causes Mitochondrial Calcium Handling Defects in MT-ND5 Mutant Cybrids
- (2016) Matthew McKenzie et al. PLoS One
- Reduced mitochondrial Ca2+ transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase
- (2015) V Granatiero et al. CELL DEATH AND DIFFERENTIATION
- SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents
- (2015) Yuzheng Zhao et al. Cell Metabolism
- Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter
- (2015) Y. Lee et al. EMBO REPORTS
- Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I
- (2015) Luke E. Formosa et al. HUMAN MOLECULAR GENETICS
- The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition
- (2015) Timothy S. Luongo et al. Cell Reports
- The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart
- (2015) Jennifer Q. Kwong et al. Cell Reports
- Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study
- (2015) Junko Shibayama et al. PLoS One
- Expansion of Biological Pathways Based on Evolutionary Inference
- (2014) Yang Li et al. CELL
- Expression Stability of Common Housekeeping Genes Is Differently Affected by Bowel Inflammation and Cancer
- (2014) Malgorzata Krzystek-Korpacka et al. INFLAMMATORY BOWEL DISEASES
- Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure
- (2013) Georgios Karamanlidis et al. Cell Metabolism
- TIMMDC1/C3orf1 Functions as a Membrane-Embedded Mitochondrial Complex I Assembly Factor through Association with the MCIA Complex
- (2013) Virginia Guarani et al. MOLECULAR AND CELLULAR BIOLOGY
- Ultrasensitive fluorescent proteins for imaging neuronal activity
- (2013) Tsai-Wen Chen et al. NATURE
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- (2013) Xin Pan et al. NATURE CELL BIOLOGY
- EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
- (2013) Y. Sancak et al. SCIENCE
- MCU encodes the pore conducting mitochondrial calcium currents
- (2013) Dipayan Chaudhuri et al. eLife
- Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics
- (2012) Brian Glancy et al. BIOCHEMISTRY
- Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance
- (2012) Cecile Vernochet et al. Cell Metabolism
- Subunit-specific Incorporation Efficiency and Kinetics in Mitochondrial Complex I Homeostasis
- (2012) Cindy E. J. Dieteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- (2012) Francesca Fieni et al. Nature Communications
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update
- (2011) X. Wang et al. NUCLEIC ACIDS RESEARCH
- A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms
- (2011) Xiaokun Shu et al. PLOS BIOLOGY
- Calcium and ATP handling in human NADH:Ubiquinone oxidoreductase deficiency
- (2009) Federica Valsecchi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondrial Ca2+ homeostasis in human NADH:ubiquinone oxidoreductase deficiency☆
- (2008) P WILLEMS et al. CELL CALCIUM
- Increased mitochondrial Ca 2+ and decreased sarcoplasmic reticulum Ca 2+ in mitochondrial myopathy
- (2008) Jan Aydin et al. HUMAN MOLECULAR GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started