期刊
CANCER JOURNAL
卷 21, 期 2, 页码 117-122出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PPO.0000000000000100
关键词
Cancer cachexia; noninvasive imaging; molecular mechanisms; treatment options
类别
资金
- Tina Brozman Foundation
- [P50 CA103175]
- [P30 CA006973]
- [R01 CA73850]
- [R01 CA82337]
- [R01 CA136576]
- [R01 CA138515]
Cancer cachexia is defined as a multifactorial syndrome characterized by an ongoing loss of skeletal muscle mass with or without loss of fat mass. The syndrome cannot be fully reversed by conventional nutritional support, and despite an increased number of studies related to cancer cachexia, the underlying mechanisms are still poorly defined, and therapeutic options are limited. This review focuses on recent studies investigating mechanisms and pathways in cancer cachexia. The role of molecular and functional imaging in identifying cachexia at an earlier stage, in identifying potential metabolic targets and pathways, and in assessing treatment efficacy is also reviewed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据