Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions

Dendritic cell vaccination in acute myeloid leukemia

(2014) Sébastien Anguille et al.   CYTOTHERAPY

Dendritic Cell-Mediated Immune Humanization of Mice: Implications for Allogeneic and Xenogeneic Stem Cell Transplantation

(2014) G. Salguero et al.   JOURNAL OF IMMUNOLOGY

Clinical use of dendritic cells for cancer therapy

(2014) Sébastien Anguille et al.   LANCET ONCOLOGY

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

(2013) J. Tel et al.   CANCER RESEARCH

Design of an Optimized Wilms’ Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo

(2013) Daphné Benteyn et al.   Molecular Therapy-Nucleic Acids

Immunotherapy of cancer in 2012

(2012) John M. Kirkwood et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Therapeutic effect of intratumoral administration of DCs with conditional expression of combination of different cytokines

(2012) Chun Huang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

T Cell Assays and MIATA: The Essential Minimum for Maximum Impact

(2012) C.M. Britten et al.   IMMUNITY

Interferon-α as Antiviral and Antitumor Vaccine Adjuvants: Mechanisms of Action and Response Signature

(2012) Eleonora Aricò et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

NK Cells: Key to Success of DC-Based Cancer Vaccines?

(2012) E. Lion et al.   ONCOLOGIST

Interleukin-15-Induced CD56+ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

(2012) Sébastien Anguille et al.   PLoS One

IFN-  enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing

(2011) F. Spadaro et al.   BLOOD

Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia

(2011) Evelien L. J. Smits et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells

(2011) J. E. Boudreau et al.   CANCER RESEARCH

Direct Effects of Type I Interferons on Cells of the Immune System

(2011) S. Hervas-Stubbs et al.   CLINICAL CANCER RESEARCH

Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells

(2011) Mercedes B. Fuertes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interferon-α in acute myeloid leukemia: an old drug revisited

(2011) S Anguille et al.   LEUKEMIA

Poly(I:C) Enhances the Susceptibility of Leukemic Cells to NK Cell Cytotoxicity and Phagocytosis by DC

(2011) Eva Lion et al.   PLoS One

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

(2010) V. F. Van Tendeloo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15R  complexes

(2010) K. G. Elpek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial

(2009) Ann Van Driessche et al.   CYTOTHERAPY

Dendritic Cell-Based Cancer Gene Therapy

(2009) Evelien L.J.M. Smits et al.   HUMAN GENE THERAPY

Acute myeloid leukemic cell lines loaded with synthetic dsRNA trigger IFN-γ secretion by human NK cells

(2008) Eva Lion et al.   LEUKEMIA RESEARCH

Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA

(2008) Aude Bonehill et al.   MOLECULAR THERAPY