siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8+ T cells in NOD/SCID/IL2Rg(null) mice

Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy

(2014) A. B. van der Waart et al.   BLOOD

Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells

(2014) J J Pen et al.   GENE THERAPY

Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8+ T Cell Immunodominance

(2014) M. F. Kotturi et al.   JOURNAL OF IMMUNOLOGY

Minor Histocompatibility Antigens and the Maternal Immune Response to the Fetus During Pregnancy

(2013) Caitlin Linscheid et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Blockade of PD-1/PD-L1 immune checkpoint during DC vaccination induces potent protective immunity against breast cancer in hu-SCID mice

(2013) Yan Ge et al.   CANCER LETTERS

Disabling Immune Tolerance by Programmed Death-1 Blockade With Pidilizumab After Autologous Hematopoietic Stem-Cell Transplantation for Diffuse Large B-Cell Lymphoma: Results of an International Phase II Trial

(2013) Philippe Armand et al.   JOURNAL OF CLINICAL ONCOLOGY

Association of Disparities in Known Minor Histocompatibility Antigens with Relapse-Free Survival and Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation

(2012) Willemijn Hobo et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

(2012) Willemijn Hobo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel Serial Positive Enrichment Technology Enables Clinical Multiparameter Cell Sorting

(2012) Christian Stemberger et al.   PLoS One

PD-1/PD-L1 Interactions Contribute to Functional T-Cell Impairment in Patients Who Relapse with Cancer After Allogeneic Stem Cell Transplantation

(2011) W. J. Norde et al.   CANCER RESEARCH

Successful generation of primary virus-specific and anti-tumor T-cell responses from the naive donor T-cell repertoire is determined by the balance between antigen-specific precursor T cells and regulatory T cells

(2011) I. Jedema et al.   HAEMATOLOGICA

Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

(2011) W. Joost Lesterhuis et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhancement of Vaccine-induced Primary and Memory CD8+ T-cell Responses by Soluble PD-1

(2011) Mi-Young Song et al.   JOURNAL OF IMMUNOTHERAPY

siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells

(2010) W. Hobo et al.   BLOOD

Dendritic Cells

(2010) Karolina Palucka et al.   CANCER JOURNAL

High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning

(2010) C. A. M. Van Bergen et al.   CANCER RESEARCH

Harnessing human dendritic cell subsets for medicine

(2010) Hideki Ueno et al.   IMMUNOLOGICAL REVIEWS

Directing dendritic cell immunotherapy towards successful cancer treatment

(2009) Rachel Lubong Sabado et al.   Immunotherapy

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters

(2008) Lotte Engell-Noerregaard et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer vaccines for established cancer: how to make them better?

(2008) Daniel M. Andrews et al.   IMMUNOLOGICAL REVIEWS

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

(2008) M. Frank-Kamenetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA